Navigation Links
New MRSA superbug emerges in Brazil
Date:4/17/2014

An international research team led by Cesar A. Arias, M.D., Ph.D., at The University of Texas Health Science Center at Houston (UTHealth) has identified a new superbug that caused a bloodstream infection in a Brazilian patient. The report appeared in the April 17 issue of The New England Journal of Medicine.

The new superbug is part of a class of highly-resistant bacteria known as methicillin-resistant Staphylococcus aureus or MRSA, which is a major cause of hospital and community-associated infections. The superbug has also acquired high levels of resistance to vancomycin, the most common and least expensive antibiotic used to treat severe MRSA infections worldwide.

Most worrisome is that genomic analyses indicated that this novel vancomycin-resistant MRSA superbug belongs to a genetic lineage that is commonly found outside hospitals (designated community-associated MRSA), said Arias, the report's senior author and an associate professor of medicine, microbiology and molecular genetics at the UTHealth Medical School.

Previous research has suggested that community-associated MRSA can disseminate rapidly among people and is responsible for the majority of skin and soft tissue infections (sores) in patients of all ages. Some of these infections can become serious and even fatal.

Since community-associated MRSA is thought to be transmitted mainly by skin contact, the new superbug may affect not only sick people or those with a weakened immune system but also healthy individuals, according to Arias. Apart from causing localized skin infections, the MRSA superbug has the ability to invade the bloodstream and may become a serious threat.

"This is the first-ever reported bloodstream infection caused by a highly vancomycin-resistant MRSA bacteria," Arias said. "If we lose vancomycin, it would make it very difficult and expensive to treat these infections," he said.

Arias and his colleagues conducted microbiological and genetic analyses of an MRSA superbug recovered from the blood of a 35-year-old Brazilian man and identified a novel transferable genetic element (plasmid) that carries the genes necessary for vancomycin resistance (vanA gene cluster).

"The presence and dissemination of community-associated MRSA containing vanA could become a serious public health concern," report the authors in the paper.

However, since this is the only documented case of this type of infection, Arias said, it is too early to tell if this specific superbug will lead to a bigger threat.

Barbara E. Murray, M.D., report co-author and director of the Division of Infectious Diseases at the UTHealth Medical School, said, "The worst resistance possible has now appeared in the community-associated MRSA clone."

What is the next step?

"There will have to be increased surveillance in South America and worldwide in the future," said Murray, who is the holder of the J. Ralph Meadows Professorship in Internal Medicine at the UTHealth Medical School and president of the Infectious Diseases Society of America.


'/>"/>

Contact: Robert Cahill
Robert.Cahill@uth.tmc.edu
713-500-3030
University of Texas Health Science Center at Houston
Source:Eurekalert  

Related medicine news :

1. NIH scientists track evolution of a superbug
2. A new weapon in the war against superbugs
3. Despite superbug crisis, progress in antibiotic development alarmingly elusive
4. Drug-Resistant Superbug May Spread Among Patients, Study Finds
5. Superbug CRE may endure in patients 1 year after initial infection: Study
6. UNC scientists unveil a superbugs secret to antibiotic resistance
7. In war with superbugs, Cedars-Sinai researchers see new weapon: Immune-boosting vitamin
8. Prosvent Emerges As Preferred Treatment For Enlarged Prostate
9. Hybrid screening strategy emerges for colorectal cancer
10. Improve Eyesight Naturally Emerges As An Alternative To Corrective Eye Surgeries: User Gets 20/ 20 Vision In Three Months - Vision Without Glasses
11. Breakthrough Drug MW151 Emerges as a Potential Competitor to Perispinally Administered Etanercept Inducing Rapid Recovery of Functions Lost to Alzheimer’s, Stroke and TBI
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New MRSA superbug emerges in Brazil
(Date:2/5/2016)... ... ... Dr. Justin Scott and Dr. Lydia Muccioli of Pure Dental Health ... in need. The event is scheduled to take place on February 27, 2016 from ... dental care to community members in need. Each patient will be given the opportunity ...
(Date:2/5/2016)... Viejo, CA (PRWEB) , ... February 05, 2016 , ... ... X. Move from on one drop zone to the next using Colorize's dynamic moving ... complements any project. This package includes a 3D slideshow environment with 1 to 5 ...
(Date:2/5/2016)... ... February 05, 2016 , ... California ... announced the debut of their latest mobile kitchen model, featuring customizable stainless steel ... modern, high-volume commercial kitchens for use anywhere in the U.S. Many of their ...
(Date:2/5/2016)... ... February 05, 2016 , ... KICVentures ( http://www.kicventures.com ... Development event in New York City on Thursday, January 21, 2016. Kingsley ... Mediacom, (both alumnus of the varsity Columbia soccer program) spoke at the event, ...
(Date:2/5/2016)... ... 05, 2016 , ... When one is tired of trying to cram belongings into spare space ... to rent a storage unit, but before hastily spending money on a unit, take these ... more space. But what one is often not told when utilizing these services are some ...
Breaking Medicine News(10 mins):
(Date:2/5/2016)... 2016 --> ... "Fetal (Labor & Delivery) and Neonatal Care Equipment Market ... Oximeter, Phototherapy/Jaundice Management Devices, CPAP, Capnograph, & Resuscitator) - ... studies the global market over the forecast period of ... 6.28 Billion in 2015 and is poised to grow ...
(Date:2/4/2016)... -- For hospitals considering enrollment in the Federal 340B ... program, the Health Resources and Services Administration,s (HRSA) recent ... , could have significant impact on plans and operations, ... Essential Insights , Daniel Neal, director ... Mega-Guidance,s key proposed changes, including a new requirement that ...
(Date:2/4/2016)... CITY, Calif. , Feb. 4, 2016 /PRNewswire/ ... "Company") today announced it has entered into a ... Exchange Commission (SEC) fully resolving the SEC,s investigation ... Act (FCPA).  Under the terms of the settlement ... of $12.8 million, including disgorgement, pre-judgment interest and ...
Breaking Medicine Technology: