Navigation Links
New Long-Term HUMIRA(R) (adalimumab) Data Show Up to Seven-Year Efficacy with Combination Treatment for Rheumatoid Arthritis
Date:6/12/2008

patients with moderate to severe RA with inadequate

response to MTX, including assessment of inhibition of radiographic

progression.

* The STAR trial: a Phase III study that evaluated the efficacy and

safety of HUMIRA when added to a standard treatment regimen for RA

in patients with inadequate response.

* DE005: a Phase I study evaluating the safety and efficacy of HUMIRA

in combination with methotrexate in methotrexate partial responders.

* DE037: a Phase I roll-over study that evaluated the safety,

pharmacokinetics and early signs of HUMIRA efficacy among RA

patients in the United States and Japan.

Efficacy

* After six months of therapy, all efficacy measures showed

significant improvements versus baseline.

* At year two, additional improvements were observed in American

College of Rheumatology (ACR) responses. ACR responses represent a

percent improvement in tender joint count, swollen joint count and

other relevant clinical measures.

* Improved response after year one was confirmed by examining

sustained clinical remission (Disease Activity Score (DAS28) of less

than 2.6) for at least three consecutive visits; sustained remission

was achieved in 42 percent of all patients after a mean of 18 +/- 17

months. DAS28 is a composite index that includes variables such as

the number of tender and swollen joints, specific laboratory values

and other measures of disease activity.

Safety

* The treatment exposure-adjusted rate of serious adverse events

(SAEs), and serious infections, declined progressively during seven

years of observation.

* Rates and types of SAEs were consistent with randomized controlled

trials, including the rate of se
'/>"/>

SOURCE Abbott
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine news :

1. Smoking may strongly increase long-term risk of eye disease
2. Long-Term Fatigue Plagues Cancer Survivors
3. Dont Ignore Tough or Long-Term Stomach Pain
4. Shaking may cause brain damage and serious long-term effects to infants
5. Sexual function affected by stem cell transplant according to long-term study
6. Smoking can harm the long-term effects of some oral surgery procedures
7. Childhood Obesity Epidemic a Long-Term Challenge
8. Conseco to Host Follow-Up Long-Term Care Conference Call
9. New Report Finds Information Technology Essential But Not Sufficient in Long-Term Care
10. No Link Between Amateur Boxing, Long-Term Brain Damage
11. No strong evidence linking amateur boxing with long-term brain injury
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/22/2014)... For Dr. Iris Hunter, a job is more than ... her life’s mission. Her extensive experience in the nonprofit sector, ... HomeCare, make it clear that Hunter’s mission is to serve ... makes a difference in the lives of others,” Hunter said. ... research, I felt ready to start on this journey as ...
(Date:10/22/2014)... Shriners Hospitals for Children® and UK HealthCare ... location of Shriners Hospitals for Children - Lexington from ... University of Kentucky Albert B. Chandler Hospital. The new ... and operated by Shriners Hospitals for Children, and designed ... their families well into the future. , “The quality ...
(Date:10/22/2014)... 22, 2014 With the Affordable Care Act ... by the American Institutes for Research (AIR) finds that three ... use health insurance, but 42 percent say they are not ... before signing up for coverage. , The AIR survey found ... percent able to calculate correctly how much they owe for ...
(Date:10/22/2014)... 2014 Healthcare professionals who are ... education at home or on-the-go via laptops, tablets ... brand new, premium Seminar-on-Demand CE courses. The new ... 2,000 hours of CE course offerings, ... experience. With such a diverse library, there’s something ...
(Date:10/22/2014)... Lintelus, Inc., an event software provider, announced ... will be speaking on the subject of “Event Technology ... 28, at the Holiday Inn in New York City. ... as a Tech Demo at 12:45pm, to educate event ... engaging event experience. , The Annual Meetings Technology Expo ...
Breaking Medicine News(10 mins):Health News:Dr. Iris Hunter to Host Grand Opening of FirstLight HomeCare Tomorrow 2Health News:Shriners Hospitals for Children - Lexington Announces Plan to Build New $47 Million Facility 2Health News:Shriners Hospitals for Children - Lexington Announces Plan to Build New $47 Million Facility 3Health News:Many Americans Fail to Ask Basic Questions Before Signing Up for Health Insurance, National Survey Finds 2Health News:Many Americans Fail to Ask Basic Questions Before Signing Up for Health Insurance, National Survey Finds 3Health News:Many Americans Fail to Ask Basic Questions Before Signing Up for Health Insurance, National Survey Finds 4Health News:Top Provider of Continuing Education at Home Releases 20 New Online Courses 2Health News:Jay Cormier, Sr. Vice President of Sales for Lintelus, Speaks about Event Technology Integration at Meetings Technology Expo in NYC 2
... found that the chance of successfully quitting can be ... their stay, and then have at least one month ... in to hospital provides an opportunity to stop smoking. ... has to stop temporarily while in hospital. People who ...
... What's billed as the world's biggest condom - a huge ... above a Dutch festival to increase safe sex awareness . ... Guinness Book of records - was commissioned by seven local ... Cross Festival in Lichtenvoorde, a small town near Almelo in ...
... the level of birth registration in certain parts of India ... year, 10 million still go unregistered . ,Two out ... not exist for government planning purposes, Plan India, a non-governmental ... deaths was made compulsory under the Registration of Births & ...
... people are unwilling or unable to stop smoking, but are ... smoke each day . ,After studying healthcare literature, ... reports that assessed methods aimed at helping people reduce use. ... cigarettes delivers clear health benefits. ,The main effort in ...
... death when seated, and not only when they are lying down, ... Childhood , a British journal. ,The findings are based ... among infants up to the age of 12 months in Quebec, ... deaths, 17, or 3.3 percent, occurred in babies who had been ...
... of extremes, boasts of almost a thousand no-sex-till-marriage organizations. ... Its brand ambassador beautiful teen Jami Waite, has been ... has risen from a single operation in Longview, Texas, ... can be abstinent, and its not weird, Waite declares. ...
Cached Medicine News:Health News:Hospital Provides an Oppurtunity to Quit Smoking 2Health News:Millions of Births Still Go Unreported in India 2Health News:Reducing Smoking - Mixed Messages and Latest Findings 2Health News:Virginity Rules-Meant To Be Broken? 2Health News:Virginity Rules-Meant To Be Broken? 3
(Date:10/22/2014)... BASKING RIDGE, N.J. , Oct. 22, 2014 ... (RMANJ), a world-renowned leader in the field ... more rapid approach to embryonic screening. The research ... American Society for Reproductive Medicine (ASRM) meeting in ... chromosome screening (CCS) and single gene defect (SGD) ...
(Date:10/22/2014)... AVACEN Medical announced today that its AVACEN ... clearance by the U.S. Food and Drug Administration. This ... the Internet for: the temporary relief of joint ... and sprains . Logo - http://photos.prnewswire.com/prnh/20141021/153513 ... is a sophisticated medical device incorporating over 3,000 firmware ...
(Date:10/22/2014)... YARDLEY, Pa. , Oct. 22, 2014 /PRNewswire/ ... of their animal health medications, a Global Pharmaceutical ... and Antares serialization technology and turnkey solution to ... Photo - http://photos.prnewswire.com/prnh/20141021/153438 ... The product that was serialized and aggregated by ...
Breaking Medicine Technology:New IVF Research Highlights Improved Genetic Screening Approach To Help Parents Have Healthier Babies 2New IVF Research Highlights Improved Genetic Screening Approach To Help Parents Have Healthier Babies 3AVACEN Medical Announces FDA Clearance of First Medical Device with Internal Game Mode 2Xyntek and Antares Serialization Solution Protects Pets Too! 2
... Mesa Laboratories, Inc. (Nasdaq: MLAB ) today announced that ... of the Company,s Board of Directors, effectively immediately. , ... "Paul,s experience and insight have been extremely helpful ... J. Sullivan , President and CEO.  "Paul managed Mesa,s Medical product line ...
... July 8 Roxane Laboratories, Inc. announced today the approval ... by the U.S. Food and Drug Administration.  The product is available ... nationwide. , , , ... Laboratories, Anastrozole Tablets are AB rated to ARIMIDEX® (anastrozole) tablets.  Annual ...
Cached Medicine Technology:Paul D. Duke Resigns From Mesa's Board of Directors 2Roxane Laboratories, Inc. Announces the Launch of Anastrozole Tablets 2Roxane Laboratories, Inc. Announces the Launch of Anastrozole Tablets 3
Hook Shaped Tip , Curved to the Left; with 30 cm long silicone tubing with connector; overall length 40mm; stainless steel...
5x6mm Loop, 2 Irrigation Ports at 10, 2 O'Clock, 18 Gauge Thin Walled 1.2mm Shaft; overall length 40mm; stainless steel...
HYDRACLEAR is our brandname for a remarkable moisture rich element that lies throughout the interior and exterior of the ACUVUE ADVANCE Brand Contact Lenses creating a unique soft, silky feel....
4-Strand Basket Retriever was developed to facilitate recovery of foreign objects from within the neuro, peripheral, and cardiovasculature, the In-Time Retrieval Device features an integrated corewir...
Medicine Products: