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New Hepatitis C Treatment Shows Promise
Date:12/3/2009

nse. If you take the drug away, does the patient relapse."

Secondly, better treatments for hepatitis C are on the horizon. Phase 3 trials for two new protease inhibitors are wrapping up. The drugs have the potential to increase the cure rate to 70 percent to 80 percent when added to the two-drug interferon/ribavirin cocktail, Bacon said.

"The bar over which new discoveries much leap is that they have to have a better cure rate than the 70 or 80 percent we are going to see inside of two years," Bacon noted.

Phase 1 clinical trials for SPC3649 in people without hepatitis C are underway, Lanford said. Phase 2 trials in patients with hepatitis C should begin next year.

More information

The U.S. Centers for Disease Control and Prevention has more on hepatitis C.



SOURCES: Robert Lanford, Ph.D., scientist, Southwest Foundation for Biomedical Research, San Antonio, Texas; Bruce Bacon, M.D., director, division of gastroenterology and hepatology, Saint Louis University, and co-director, Saint Louis University Liver Center, St. Louis; Dec. 3, 2009, Science, online


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