Navigation Links
New Guidelines Issued on Hormone Receptor Testing for Breast Cancer
Date:4/20/2010

Up to 20% of current results may be inaccurate, study says

TUESDAY, April 20 (HealthDay News) -- The American Society of Clinical Oncology and the College of American Pathologists have issued new guidelines to improve the accuracy of the testing of estrogen and progesterone receptors in breast cancer patients.

The growth of as many as two-thirds of breast cancers are thought to be affected by the action of the estrogen-receptor pathway.

Estrogen (ER) and progesterone receptor (PgR) testing allows doctors to determine whether a patient's breast cancer fits into that group. In that case, the patient may be eligible to be treated with so-called endrocrine therapies -- including the drug tamoxifen -- that can improve survival.

But there's a problem: Worldwide, as many as 10 percent to 20 percent of these screens, known as immunohistochemistry tests, may be wrong.

"There is clearly a need to accurately identify breast cancer subtypes as ER- and/or PgR-positive to help us identify those patients most likely to benefit from endocrine therapy and minimize the risk of potentially denying effective and lifesaving therapy to patients incorrectly labeled as having ER/PgR-negative invasive disease, while allowing patients with true ER/PgR-negative disease to be considered for other therapies," Dr. Antonio C. Wolff, co-chair of a joint panel on hormone receptor testing in breast cancer and a professor of oncology at Johns Hopkins Kimmel Cancer Center in Baltimore, said in a news release.

Among a long list of recommendations, the guidelines encourage regular testing in newly diagnosed invasive breast cancers, uniform testing procedures and validation of tests.

The new guidelines were published April 19 in the Journal of Clinical Oncology and the Archives of Pathology & Laboratory Medicine.

More information

For more on breast cancer, see the U.S. National Library of Medicine.



-- Randy Dotinga



SOURCE: American Society of Clinical Oncology, news release, April 19, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. NICE guidelines ration affordable osteoporosis drugs
2. Sunquest Information Systems Supports New Meaningful Use Guidelines for Laboratories Transferring H1N1 Results
3. ASTRO, ACR issue IGRT, SBRT guidelines
4. Jefferson neurosurgeon helps draft new treatment guidelines for brain metastases
5. Change in mammography guidelines questioned
6. Milliman Care Guidelines Offers Online Interrater Reliability Tool and Training
7. New Guidelines Suggest Botox for Cerebral Palsy
8. NCCN Guidelines for Non-Small Cell Lung Cancer Updated to Incorporate Maintenance Therapy
9. ASGE issues guidelines on management of antithrombotic agents for endoscopic procedures
10. New Guidelines Urge A1C Test for Diabetes Diagnosis
11. Fewer headaches on the horizon thanks to latest guidelines
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... ... giving viewers the lowdown on sciatica in a new episode of "Success Files," ... on current events and innovation and investigates each subject in-depth with passion and ...
(Date:10/12/2017)... ... October 12, 2017 , ... First Healthcare Compliance (FHC), ... will showcase a range of technology and learning solutions at the 68th Annual ... Expo to be held October 14–18, 2017 at the Mandalay Bay Resort in ...
(Date:10/12/2017)... ... October 12, 2017 , ... IsoComforter, Inc. ( https://isocomforter.com ... the introduction of an innovative new design of the shoulder pad. The shoulder ... maximum comfort while controlling your pain while using cold therapy. By utilizing ice and ...
(Date:10/12/2017)... LOS ANGELES (PRWEB) , ... October 12, 2017 ... ... of Parsa Mohebi Hair Restoration, has recently contributed a medical article to the ... doctors, on cosmetictown.com. Dr. Mohebi’s article spotlights the hair transplant procedure known as ...
(Date:10/12/2017)... ... October 12, 2017 , ... Women-owned ... Michigan’s 2017 Best and Brightest in Wellness® by Best and Brightest. OnSite Wellness ... on Friday, Oct. 20 from 7:30 a.m. to 2 p.m. at the Henry ...
Breaking Medicine News(10 mins):
(Date:10/4/2017)... to the Centers for Disease Control and Prevention (CDC), influenza vaccination ... is helping communities across Massachusetts , Connecticut ... flu shots through the end of the month. *Some exclusions ... ... shot is by the end of October, according to the Centers for ...
(Date:10/2/2017)...  AllianceRx Walgreens Prime, the combined central specialty pharmacy ... benefit manager Prime Therapeutics LLC (Prime), today officially began ... unveiling of new signage at its headquarters in ... a few other company-owned facilities across the country. This ... of whom will begin to see the AllianceRx Walgreens ...
(Date:9/28/2017)... , Sept. 28, 2017 Cohen Veterans Bioscience ... the use of wearable and home sensors for real-time ... Early Signal Foundation, a nonprofit organization focused on disruptive ... provide an affordable analytical system to record and integrate ... ...
Breaking Medicine Technology: