Navigation Links
New Guidelines Issued on Hormone Receptor Testing for Breast Cancer

Up to 20% of current results may be inaccurate, study says

TUESDAY, April 20 (HealthDay News) -- The American Society of Clinical Oncology and the College of American Pathologists have issued new guidelines to improve the accuracy of the testing of estrogen and progesterone receptors in breast cancer patients.

The growth of as many as two-thirds of breast cancers are thought to be affected by the action of the estrogen-receptor pathway.

Estrogen (ER) and progesterone receptor (PgR) testing allows doctors to determine whether a patient's breast cancer fits into that group. In that case, the patient may be eligible to be treated with so-called endrocrine therapies -- including the drug tamoxifen -- that can improve survival.

But there's a problem: Worldwide, as many as 10 percent to 20 percent of these screens, known as immunohistochemistry tests, may be wrong.

"There is clearly a need to accurately identify breast cancer subtypes as ER- and/or PgR-positive to help us identify those patients most likely to benefit from endocrine therapy and minimize the risk of potentially denying effective and lifesaving therapy to patients incorrectly labeled as having ER/PgR-negative invasive disease, while allowing patients with true ER/PgR-negative disease to be considered for other therapies," Dr. Antonio C. Wolff, co-chair of a joint panel on hormone receptor testing in breast cancer and a professor of oncology at Johns Hopkins Kimmel Cancer Center in Baltimore, said in a news release.

Among a long list of recommendations, the guidelines encourage regular testing in newly diagnosed invasive breast cancers, uniform testing procedures and validation of tests.

The new guidelines were published April 19 in the Journal of Clinical Oncology and the Archives of Pathology & Laboratory Medicine.

More information

For more on breast cancer, see the U.S. National Library of Medicine.

-- Randy Dotinga

SOURCE: American Society of Clinical Oncology, news release, April 19, 2010

Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. NICE guidelines ration affordable osteoporosis drugs
2. Sunquest Information Systems Supports New Meaningful Use Guidelines for Laboratories Transferring H1N1 Results
3. ASTRO, ACR issue IGRT, SBRT guidelines
4. Jefferson neurosurgeon helps draft new treatment guidelines for brain metastases
5. Change in mammography guidelines questioned
6. Milliman Care Guidelines Offers Online Interrater Reliability Tool and Training
7. New Guidelines Suggest Botox for Cerebral Palsy
8. NCCN Guidelines for Non-Small Cell Lung Cancer Updated to Incorporate Maintenance Therapy
9. ASGE issues guidelines on management of antithrombotic agents for endoscopic procedures
10. New Guidelines Urge A1C Test for Diabetes Diagnosis
11. Fewer headaches on the horizon thanks to latest guidelines
Post Your Comments:
(Date:6/26/2016)... ... June 26, 2016 , ... Pixel Film Studios Released ProSlice ... "Film editors can give their videos a whole new perspective by using the ... of Pixel Film Studios. , ProSlice Levels contains over 30 Different presets to ...
(Date:6/25/2016)... ... 25, 2016 , ... Austin residents seeking Mohs surgery services, can now turn ... to Dr. Russell Peckham for medical and surgical dermatology. , Dr. Dorsey brings specialization ... selective fellowship in Mohs Micrographic Surgery completed by Dr. Dorsey was under the direction ...
(Date:6/25/2016)... ... June 25, 2016 , ... Dr. Calvin ... injury. Recently, he has implemented orthobiologic procedures as a method for treating his ... of the first doctors to perform the treatment. Orthobiologics are substances that orthopaedic ...
(Date:6/24/2016)... ... 24, 2016 , ... June 19, 2016 is World Sickle Cell Observance Day. ... the benefits of holistic treatments, Serenity Recovery Center of Marne, Michigan, has ... , Sickle Cell Disease (SCD) is a disorder of the red blood cells, which ...
(Date:6/24/2016)... Diego, CA (PRWEB) , ... June 24, 2016 , ... ... with the American Cancer Society and the Road To Recovery® program to drive cancer ... to seniors and other adults to ensure the highest quality of life and ongoing ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... Roche (SIX: RO, ROG; OTCQX: RHHBY) announced that it ... (procalcitonin) assay as a dedicated testing solution for people ... Roche is the first IVD company in the U.S ... assessment and management. PCT is a sepsis-specific ... blood can aid clinicians in assessing the risk of ...
(Date:6/23/2016)... MOUNTAIN VIEW, Calif. , June 23, 2016 ... 9:00 a.m. CST on Thursday, July 7, 2016 , , ... ) , , , , EXPERT PANELISTS:  ... Sciences, Nitin Naik; Senior Industry Analyst, Christi Bird; Senior Industry Analyst, ... The global pharmaceutical industry is witnessing ...
(Date:6/23/2016)... 2016 The vast majority of dialysis patients ... Treatments are usually 3 times a week, with treatment ... travel time, equipment preparation and wait time.  This regimen ... for patients who are elderly and frail.  Many elderly ... rehabilitation centers for some duration of time. ...
Breaking Medicine Technology: