Navigation Links
New Guidelines Issued for Combining HIV, Seizure Meds
Date:1/4/2012

WEDNESDAY, Jan. 4 (HealthDay News) -- Physicians need to take care when prescribing seizure medication to HIV/AIDS patients to prevent harmful interactions between drugs, experts warn.

The cautionary note from the American Academy of Neurology (AAN) has led to the issuance of a new AAN guideline, which was developed in consultation with the International League Against Epilepsy.

"It is important that patients know exactly which drugs they are taking and provide that information to all prescribing health care providers caring for them," lead guideline author Dr. Gretchen L. Birbeck, of Michigan State University in East Lansing, said in an AAN news release.

"Doctors may need to watch and adjust drug doses in people with HIV/AIDS who take seizure drugs," added Birbeck, who is also an AAN fellow.

Seizures and related disorders are not uncommon among HIV patients, according to Birbeck and colleagues. It is estimated that at least 10 percent of HIV patients experience seizures, they noted.

In the new guideline, which is published in the Jan. 4 online editions of both Neurology and Epilepsia, the research team cautioned that effectiveness of either set of drugs can be compromised when specific seizure medications are taken alongside certain HIV/AIDS treatments. Increased toxicity is another potential issue.

For example, levels of certain HIV medications -- such as phenytoin, phenobarbital and carbamazepine -- actually drop off when they come in contact with seizure drugs. The risk: an HIV drug regimen might fail, the authors pointed out.

One way Birbeck's team hopes to mitigate against such risk is to outline the correct dosages of seizure drugs. They noted that dangerous drug interactions may be avoidable if medications are prescribed in the right amounts.

The team also acknowledged that the threat of harmful drug interactions is highest where drug choices are the most curtailed. That means that patients in poorer countries, where most HIV/AIDS patients now live, are particularly vulnerable to this dynamic.

"Future research should target epilepsy and HIV/AIDS drug combinations where choices are limited, such as in developing countries, to better understand the risk of these drug interactions," Birbeck said in the news release.

More information

For more on seizures, visit the Epilepsy Foundation.

-- Alan Mozes

SOURCE: American Academy of Neurology, news release, Jan. 4, 2012


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. DMP for diabetes type 2: Current guidelines indicate some need for revision
2. CDC Issues New TB Treatment Guidelines
3. AIUM officially recognizes ACEP Emergency Ultrasound Guidelines
4. Few Contact Lens Users Follow All Care Guidelines, Study Finds
5. New Guidelines for Treating Psoriasis When Pregnant or Nursing
6. New Canadian Guidelines Also Support No Routine Mammograms Until 50
7. Canadian breast cancer screening guidelines would cost thousands of lives
8. New breast cancer screening guidelines released
9. New Stanford model establishes guidelines for earlier cancer detection
10. Few doctors follow sudden cardiac death screening guidelines for athletes
11. New Guidelines Urge Cholesterol Check for All Kids Ages 9 to 11
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Guidelines Issued for Combining HIV, Seizure Meds
(Date:6/25/2016)... ... June 25, 2016 , ... Dr. Calvin Johnson has ... he has implemented orthobiologic procedures as a method for treating his patients. The ... first doctors to perform the treatment. Orthobiologics are substances that orthopaedic surgeons use ...
(Date:6/24/2016)... ... June 24, 2016 , ... Those who have experienced traumatic events ... turn to unhealthy avenues, such as drug or alcohol abuse, as a coping mechanism. ... tools for healthy coping following a traumatic event. , Trauma sufferers tend to feel ...
(Date:6/24/2016)... ... 2016 , ... Global law firm Greenberg Traurig, P.A. announced that 20 Florida ... their peers for this recognition are considered among the top 2 percent of lawyers ... as members of this year’s Legal Elite Hall of Fame: Miami Shareholders Mark ...
(Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. ... magazine’s Code Talker Award, an essay contest in which patients and their families pay ... be presented at the 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference ...
(Date:6/24/2016)... ... June 24, 2016 , ... Strategic ... Frederick area economy by obtaining investment capital for emerging technology companies. SCP ... that have already resulted in more than a million dollars of capital investment ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 24, 2016 Research and Markets has ... Companion Diagnostic Tests" report to their offering. ... Diagnostics The World Market for Companion Diagnostics ... diagnostics. Market analysis in the report includes the following: ... Vitro Diagnostic Kits) by Region (N. America, EU, ROW), 2015-2020 ...
(Date:6/23/2016)... June 23, 2016  MedSource announced today that ... e-clinical software solution of choice.  This latest decision ... value to their clients by offering a state-of-the-art ... relationship establishes nowEDC as the EDC platform of ... full-service clients.  "nowEDC has long been a preferred ...
(Date:6/23/2016)... , June 23, 2016 Roche (SIX: ... 510(k) clearance for its Elecsys BRAHMS PCT (procalcitonin) assay ... sepsis or septic shock. With this clearance, Roche is ... a fully integrated solution for sepsis risk assessment and ... with bacterial infection and PCT levels in blood can ...
Breaking Medicine Technology: