Navigation Links
New Guidelines Issued for Combining HIV, Seizure Meds
Date:1/4/2012

WEDNESDAY, Jan. 4 (HealthDay News) -- Physicians need to take care when prescribing seizure medication to HIV/AIDS patients to prevent harmful interactions between drugs, experts warn.

The cautionary note from the American Academy of Neurology (AAN) has led to the issuance of a new AAN guideline, which was developed in consultation with the International League Against Epilepsy.

"It is important that patients know exactly which drugs they are taking and provide that information to all prescribing health care providers caring for them," lead guideline author Dr. Gretchen L. Birbeck, of Michigan State University in East Lansing, said in an AAN news release.

"Doctors may need to watch and adjust drug doses in people with HIV/AIDS who take seizure drugs," added Birbeck, who is also an AAN fellow.

Seizures and related disorders are not uncommon among HIV patients, according to Birbeck and colleagues. It is estimated that at least 10 percent of HIV patients experience seizures, they noted.

In the new guideline, which is published in the Jan. 4 online editions of both Neurology and Epilepsia, the research team cautioned that effectiveness of either set of drugs can be compromised when specific seizure medications are taken alongside certain HIV/AIDS treatments. Increased toxicity is another potential issue.

For example, levels of certain HIV medications -- such as phenytoin, phenobarbital and carbamazepine -- actually drop off when they come in contact with seizure drugs. The risk: an HIV drug regimen might fail, the authors pointed out.

One way Birbeck's team hopes to mitigate against such risk is to outline the correct dosages of seizure drugs. They noted that dangerous drug interactions may be avoidable if medications are prescribed in the right amounts.

The team also acknowledged that the threat of harmful drug interactions is highest where drug choices are the most curtailed. That means that patients in poorer countries, where most HIV/AIDS patients now live, are particularly vulnerable to this dynamic.

"Future research should target epilepsy and HIV/AIDS drug combinations where choices are limited, such as in developing countries, to better understand the risk of these drug interactions," Birbeck said in the news release.

More information

For more on seizures, visit the Epilepsy Foundation.

-- Alan Mozes

SOURCE: American Academy of Neurology, news release, Jan. 4, 2012


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. DMP for diabetes type 2: Current guidelines indicate some need for revision
2. CDC Issues New TB Treatment Guidelines
3. AIUM officially recognizes ACEP Emergency Ultrasound Guidelines
4. Few Contact Lens Users Follow All Care Guidelines, Study Finds
5. New Guidelines for Treating Psoriasis When Pregnant or Nursing
6. New Canadian Guidelines Also Support No Routine Mammograms Until 50
7. Canadian breast cancer screening guidelines would cost thousands of lives
8. New breast cancer screening guidelines released
9. New Stanford model establishes guidelines for earlier cancer detection
10. Few doctors follow sudden cardiac death screening guidelines for athletes
11. New Guidelines Urge Cholesterol Check for All Kids Ages 9 to 11
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Guidelines Issued for Combining HIV, Seizure Meds
(Date:5/26/2017)... ... May 26, 2017 , ... Water damage to the flooring of several ... had left education officials with a number of critical issues to address before students ... to be accomplished with little or no disruption to class schedules. Second, the project ...
(Date:5/24/2017)... ... May 24, 2017 , ... In modern research, success depends ... instruments for research and understanding the basic principles that were designed to drive ... innovations in stereo microscopy for brightfield and fluorescence typically used in laboratories working ...
(Date:5/24/2017)... ... 24, 2017 , ... Altec Products, Inc., a leader in enterprise ... one-day technology conference in San Diego, CA. , At nVerge 2017, Altec will ... utilize and enhance their Sage ERP solutions by providing improved visibility and control to ...
(Date:5/24/2017)... ... May 24, 2017 , ... Drs. ... NY, who have now spent 10 years as clinical instructors for the reputable ... College of Dentistry. Through the program, private practitioners receive cutting-edge clinical training and ...
(Date:5/24/2017)... ... , ... Patients who want to receive cosmetic dentistry procedures such as Invisalign® ... for a consultation, with or without a referral. Dr. Bedich enjoys improving the appearance ... , Dr. Bedich offers a variety of cosmetic dentistry services at his practice that ...
Breaking Medicine News(10 mins):
(Date:5/10/2017)... MARLBOROUGH, Mass., May 10, 2017 Hologic, Inc. ... financial results for the fiscal second quarter ended April ... (EPS) of $1.84 increased 666.7% compared to the prior ... business resulted in a significant gain, while non-GAAP diluted ... increased 3.2%, or 3.8% in constant currency terms.  Excluding ...
(Date:5/10/2017)... Md. , May 10, 2017 CSSi, ... solutions for the clinical research industry, is proud to ... www.CSSiEnroll.com . The new website features both enriched content ... user experience and enhances the company,s already well-established position ... industry. "After many months of hard ...
(Date:5/9/2017)... 9, 2017  Semler Scientific, Inc. (OTCQB: SMLR), ... to improve the clinical effectiveness and efficiency of ... first quarter ended March 31, 2017. ... customers to identify when preventive care options are ... like heart attacks or strokes occur," said ...
Breaking Medicine Technology: