Navigation Links
New Genetic Analysis Might Boost Breast Cancer Care
Date:12/16/2008

Scientists say they've found a more accurate cell-based prognostic tool

TUESDAY, Dec. 16 (HealthDay News) -- Examining subnetworks of genetic activity in a patient's tumor better predicts the spread of breast cancer than conventional techniques, researchers say.

University of California at San Diego scientists, working with Korean researchers, used bioinformatic algorithms to identify these subnetworks. They then mapped the gene activity to the many networks of signaling pathways and protein complexes that prior research had found in human cells.

The scientists explained that conventional "rapid microarray" technology allows cancers to be classified by gene expression, or activity patterns, but this system is imprecise because cells from a single tumor sample can have genes switched on in some cells (from one part of the tumor) that are inactive elsewhere.

The researchers' new work enabled them to identify subnetworks in which aggregate gene expression patterns can distinguish between patient groups.

They also uncovered many genes associated with breast cancer that had not been identified by previous gene microarray profiles.

The researcher team is now applying its analysis system to other cancers. These insights could give doctors a new tool for diagnosis and prognosis, they say.

The findings are scheduled to be presented Monday at the American Society for Cell Biology's annual meeting, in San Francisco.

More information

The American Cancer Society has more about breast cancer.



-- Kevin McKeever



SOURCE: American Society for Cell Biology, news release, Dec. 15, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Genetic Variants Tied to Obesity
2. Genetic Link Between Type 1 Diabetes, Celiac Disease Seen
3. Genetic Markers Identified for Alcohol Response in UCSF Gallo Study
4. PTSD Risk Rooted in Stress and Genetics
5. New technique enables faster genetic diagnosis for hereditary diseases
6. Texas and North Carolina Students Tackle Lifesaving Research in Chemistry and Genetics, Taking Home the Grand Prize at Nations Premier High School Science Competition
7. The SCOOTER Store Donates Power Wheelchair to Texas Teenager With Rare Genetic Disorders
8. Few Ontario women with invasive ovarian cancer referred for genetic testing of breast cancer genes
9. Novel bioreactor enhances interleukin-12 production in genetically-modified tobacco plants
10. Genetic breakdown in Fanconi anemia may have link to HPV-associated cancer
11. Understanding donor-recipient genetics could decrease early kidney transplant complications
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Genetic Analysis Might Boost Breast Cancer Care
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... for human induced pluripotent stem (iPS) cells and other difficult to transfect cells, ... Cloning Medium. The PluriQ™ G9™ Gene Editing System is a complete ...
(Date:6/24/2016)... ... June 24, 2016 , ... To ... infrastructure. Most providers, however, are unsure how to move forward, given the need ... define a path forward tailored to an organization’s specific needs. , PYA Principal ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... SpiritQuest Sedona ... heart of West Sedona, surrounded by famous vortex sites: Cathedral Rock, Airport Mesa, and ... partner properties – the Lodge at Sedona as well as the Sedona Rouge, both ...
(Date:6/23/2016)... (PRWEB) , ... June 23, 2016 , ... An ... may expose a possible link between head and neck cancer in individuals with unhealthy ... the study were evaluated based on whether they had gum disease, brushed their teeth ...
(Date:6/23/2016)... ... 23, 2016 , ... SyncDog, Inc. , the leading ... is featured in the current issue of Silicon Review magazine. Silicon ... technology solutions and features them in their magazine. The magazine allows top-level executives ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... FRANKLIN, Tenn. , June 23, 2016 ... for automating, integrating and transforming the patient ... launch of several innovative new products and ... depth of its revenue cycle offerings. These ... establish more efficient workflows, remain compliant in ...
(Date:6/23/2016)... , June 23, 2016 Leading ... that address medical conditions resulting from a breakdown ... has appointed Greg Doyle as chief ... Leading BioSciences, executive management team and board of ... chief financial officer. He will provide continued leadership ...
(Date:6/23/2016)... -- On Wednesday, June 22, 2016, the NASDAQ ... Dow Jones Industrial Average edged 0.27% lower to finish at ... Stock-Callers.com has initiated coverage on the following equities: Alkermes PLC ... AMAG ), IDEXX Laboratories Inc. (NASDAQ: IDXX ... Learn more about these stocks by accessing their free trade ...
Breaking Medicine Technology: