Navigation Links
New Genetic Analysis Might Boost Breast Cancer Care
Date:12/16/2008

Scientists say they've found a more accurate cell-based prognostic tool

TUESDAY, Dec. 16 (HealthDay News) -- Examining subnetworks of genetic activity in a patient's tumor better predicts the spread of breast cancer than conventional techniques, researchers say.

University of California at San Diego scientists, working with Korean researchers, used bioinformatic algorithms to identify these subnetworks. They then mapped the gene activity to the many networks of signaling pathways and protein complexes that prior research had found in human cells.

The scientists explained that conventional "rapid microarray" technology allows cancers to be classified by gene expression, or activity patterns, but this system is imprecise because cells from a single tumor sample can have genes switched on in some cells (from one part of the tumor) that are inactive elsewhere.

The researchers' new work enabled them to identify subnetworks in which aggregate gene expression patterns can distinguish between patient groups.

They also uncovered many genes associated with breast cancer that had not been identified by previous gene microarray profiles.

The researcher team is now applying its analysis system to other cancers. These insights could give doctors a new tool for diagnosis and prognosis, they say.

The findings are scheduled to be presented Monday at the American Society for Cell Biology's annual meeting, in San Francisco.

More information

The American Cancer Society has more about breast cancer.



-- Kevin McKeever



SOURCE: American Society for Cell Biology, news release, Dec. 15, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Genetic Variants Tied to Obesity
2. Genetic Link Between Type 1 Diabetes, Celiac Disease Seen
3. Genetic Markers Identified for Alcohol Response in UCSF Gallo Study
4. PTSD Risk Rooted in Stress and Genetics
5. New technique enables faster genetic diagnosis for hereditary diseases
6. Texas and North Carolina Students Tackle Lifesaving Research in Chemistry and Genetics, Taking Home the Grand Prize at Nations Premier High School Science Competition
7. The SCOOTER Store Donates Power Wheelchair to Texas Teenager With Rare Genetic Disorders
8. Few Ontario women with invasive ovarian cancer referred for genetic testing of breast cancer genes
9. Novel bioreactor enhances interleukin-12 production in genetically-modified tobacco plants
10. Genetic breakdown in Fanconi anemia may have link to HPV-associated cancer
11. Understanding donor-recipient genetics could decrease early kidney transplant complications
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Genetic Analysis Might Boost Breast Cancer Care
(Date:2/11/2016)... ... 2016 , ... Be Well Medical Group (Be Well) is pleased ... at 108 South Columbus St, Suite 201, Alexandria, VA. Be Well Medical Group is ... the convenience of their homes, offices or at the practices’ local office. It is ...
(Date:2/11/2016)... ... , ... The book, “Computers Should Just Work!”, provides a basic, non-techie education ... consultant before signing a contract and how to spot an incompetent or dishonest IT ... on e-mail and technology, it’s more important than ever to make sure the company ...
(Date:2/10/2016)... (PRWEB) , ... February 10, 2016 , ... ... practitioner, is known locally for a series of therapeutic sessions to help Los ... their characters and in their lives. The series, known as “Mindfulness for Actors ...
(Date:2/10/2016)... ... February 10, 2016 , ... MetLoop CEO Jay ... 2.0 version at the International Roofing Expo in Orlando, Florida on February 17-19. ... most advanced weather technology in the hands of consumers, roofing contractors, manufacturers and ...
(Date:2/10/2016)... ... February 10, 2016 , ... The Wickman Agency in ... assist the local community. Pledging to select a new beneficiary every 60 days, ... area. Their goal is to bring community awareness to important local causes by ...
Breaking Medicine News(10 mins):
(Date:2/10/2016)... -- Fotona, based in the U.S. and Europe ... Lightwalker dental laser at the upcoming 151 st Midwinter ... in booth #4815. The ST PRO is a full featured ... features of the award winning, industry leading Lightwalker ATS. At an ... be very attractive to many dentists hesitating to incorporate lasers ...
(Date:2/10/2016)... Vanda Pharmaceuticals Inc. (Vanda) (NASDAQ: VNDA ), today ... and full year ended December 31, 2015. ... transformational year for Vanda with the continued growth of ... of HETLIOZ for Non-24," said Mihael H. Polymeropoulos, M.D., ... our U.S. product portfolio builds on this success and ...
(Date:2/10/2016)... 2016 A new report from business intelligence provider GBI ... the Alzheimer,s disease market will more than double from just under $5 billion ... Growth Rate (CAGR) of 11%. Canada , ... Spain , the UK, and Japan , ... --> Canada , France , ...
Breaking Medicine Technology: