Navigation Links
New Genetic Analysis Might Boost Breast Cancer Care
Date:12/16/2008

Scientists say they've found a more accurate cell-based prognostic tool

TUESDAY, Dec. 16 (HealthDay News) -- Examining subnetworks of genetic activity in a patient's tumor better predicts the spread of breast cancer than conventional techniques, researchers say.

University of California at San Diego scientists, working with Korean researchers, used bioinformatic algorithms to identify these subnetworks. They then mapped the gene activity to the many networks of signaling pathways and protein complexes that prior research had found in human cells.

The scientists explained that conventional "rapid microarray" technology allows cancers to be classified by gene expression, or activity patterns, but this system is imprecise because cells from a single tumor sample can have genes switched on in some cells (from one part of the tumor) that are inactive elsewhere.

The researchers' new work enabled them to identify subnetworks in which aggregate gene expression patterns can distinguish between patient groups.

They also uncovered many genes associated with breast cancer that had not been identified by previous gene microarray profiles.

The researcher team is now applying its analysis system to other cancers. These insights could give doctors a new tool for diagnosis and prognosis, they say.

The findings are scheduled to be presented Monday at the American Society for Cell Biology's annual meeting, in San Francisco.

More information

The American Cancer Society has more about breast cancer.



-- Kevin McKeever



SOURCE: American Society for Cell Biology, news release, Dec. 15, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Genetic Variants Tied to Obesity
2. Genetic Link Between Type 1 Diabetes, Celiac Disease Seen
3. Genetic Markers Identified for Alcohol Response in UCSF Gallo Study
4. PTSD Risk Rooted in Stress and Genetics
5. New technique enables faster genetic diagnosis for hereditary diseases
6. Texas and North Carolina Students Tackle Lifesaving Research in Chemistry and Genetics, Taking Home the Grand Prize at Nations Premier High School Science Competition
7. The SCOOTER Store Donates Power Wheelchair to Texas Teenager With Rare Genetic Disorders
8. Few Ontario women with invasive ovarian cancer referred for genetic testing of breast cancer genes
9. Novel bioreactor enhances interleukin-12 production in genetically-modified tobacco plants
10. Genetic breakdown in Fanconi anemia may have link to HPV-associated cancer
11. Understanding donor-recipient genetics could decrease early kidney transplant complications
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Genetic Analysis Might Boost Breast Cancer Care
(Date:10/13/2017)... ... October 13, 2017 , ... Southern ... and Jennifer Huggins, PharmD ’17, along with clinical associate professor Janice Frueh, ... cardiovascular diseases during the 15th Annual Women’s Health Conference. The SIU School ...
(Date:10/13/2017)... ... 13, 2017 , ... Many families have long-term insurance that covers care for ... a waiver for care if the client has a cognitive impairment diagnosis. , ... care, is often waived, so the benefits from their insurance start immediately,” said Mechell ...
(Date:10/13/2017)... ... October 13, 2017 , ... Global Healthcare Management’s 4th Annual Kids ... Milford, NJ. This free event, sponsored by Global Healthcare Management’s CEO, Jon Letko, ... run is geared towards children of all ages; it is a non-competitive, non-timed event, ...
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, a leader ... been awarded a contract by the Center for Medicare and Medicaid Services (CMS). ... the enterprise use of Agile methodologies in a consistent and high value manner ...
(Date:10/12/2017)... ... October 12, 2017 , ... First Healthcare Compliance (FHC), an ... showcase a range of technology and learning solutions at the 68th Annual American ... to be held October 14–18, 2017 at the Mandalay Bay Resort in Las ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... , Oct. 11, 2017  Hill-Rom Holdings, Inc. ... Aspen Surgical facility in Las Piedras, Puerto ... scalpels and blades. ... that the facility sustained minor structural damage, temporary loss ... Maria. Repairs have been completed, manufacturing operations have resumed, ...
(Date:10/7/2017)... 2017   Provista, a proven leader in ... in purchasing power, today announced a new resource area ... Newsroom is the online home for case studies, ... bios, news releases, slideshows and events. ... of resources at their fingertips, viewers can also watch ...
(Date:10/4/2017)... , Oct. 4, 2017  According to the Centers for Disease Control ... of October . PhysicianOne Urgent Care is helping communities across ... NY , by offering no-cost* flu shots through the end of ... by certain health insurance regulations. ... best time to get a flu shot is by the end of ...
Breaking Medicine Technology: