Navigation Links
New Genetic Analysis Might Boost Breast Cancer Care
Date:12/16/2008

Scientists say they've found a more accurate cell-based prognostic tool

TUESDAY, Dec. 16 (HealthDay News) -- Examining subnetworks of genetic activity in a patient's tumor better predicts the spread of breast cancer than conventional techniques, researchers say.

University of California at San Diego scientists, working with Korean researchers, used bioinformatic algorithms to identify these subnetworks. They then mapped the gene activity to the many networks of signaling pathways and protein complexes that prior research had found in human cells.

The scientists explained that conventional "rapid microarray" technology allows cancers to be classified by gene expression, or activity patterns, but this system is imprecise because cells from a single tumor sample can have genes switched on in some cells (from one part of the tumor) that are inactive elsewhere.

The researchers' new work enabled them to identify subnetworks in which aggregate gene expression patterns can distinguish between patient groups.

They also uncovered many genes associated with breast cancer that had not been identified by previous gene microarray profiles.

The researcher team is now applying its analysis system to other cancers. These insights could give doctors a new tool for diagnosis and prognosis, they say.

The findings are scheduled to be presented Monday at the American Society for Cell Biology's annual meeting, in San Francisco.

More information

The American Cancer Society has more about breast cancer.



-- Kevin McKeever



SOURCE: American Society for Cell Biology, news release, Dec. 15, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Genetic Variants Tied to Obesity
2. Genetic Link Between Type 1 Diabetes, Celiac Disease Seen
3. Genetic Markers Identified for Alcohol Response in UCSF Gallo Study
4. PTSD Risk Rooted in Stress and Genetics
5. New technique enables faster genetic diagnosis for hereditary diseases
6. Texas and North Carolina Students Tackle Lifesaving Research in Chemistry and Genetics, Taking Home the Grand Prize at Nations Premier High School Science Competition
7. The SCOOTER Store Donates Power Wheelchair to Texas Teenager With Rare Genetic Disorders
8. Few Ontario women with invasive ovarian cancer referred for genetic testing of breast cancer genes
9. Novel bioreactor enhances interleukin-12 production in genetically-modified tobacco plants
10. Genetic breakdown in Fanconi anemia may have link to HPV-associated cancer
11. Understanding donor-recipient genetics could decrease early kidney transplant complications
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Genetic Analysis Might Boost Breast Cancer Care
(Date:4/23/2014)... testosterone falls below normal levels are more likely to ... heart disease and type 2 diabetes. A new simple ... testing and possible treatment is described in an article ... publication from Mary Ann Liebert, Inc., publishers. The article ... Health website at http://www.liebertpub.com/jmh . ...
(Date:4/23/2014)... accessible detection methods that can rapidly screen a ... single cell inside that population has been seriously ... , In the Royal Society of Chemistry journal ... he and his coworkers have developed a novel ... protein ( Chem. Sci. , 2014, DOI: 10.1039/C4SC00578C, ...
(Date:4/23/2014)... health benefits of probiotics, antioxidants and other nutritional compounds, ... chemical industry is getting in on the action. But ... so the industry is responding with clinical research to ... in Chemical & Engineering News (C&EN), the ... Melody M. Bomgardner, a senior editor at C&EN, writes ...
(Date:4/23/2014)... country as wealthy as the United States, it may come ... have access to adequate food due to lack of money ... Recent research at the University of Illinois using data from ... the seniors who are dealing with hunger are also facing ... percent of Americans over age 60 faced the threat of ...
(Date:4/23/2014)... A team of scientists led by a researcher from ... the National University of Singapore has identified the cancer ... opens up the possibility of developing new drugs for ... cancers. , The research group, led by Dr Chan ... for the first time that a cancer-specific variant of ...
Breaking Medicine News(10 mins):Health News:Following a protein's travel inside cells is key to improving patient monitoring, drug development 2Health News:More Americans in their golden years are going hungry 2Health News:Scientists identify cancer specific cell for potential treatment of gastric cancer 2Health News:Scientists identify cancer specific cell for potential treatment of gastric cancer 3
... are at a greater risk of catching bird flu, as the ... ,A study on cats in areas where outbreaks have ... than thought. It raises the chilling prospect that the disease could ... human pandemic. And it shows that should bird flu ever break ...
... have patented a device, which is capable of the ... by various bacteria, notable amongst which are Salmonella, Campylobacter ... due to food poisoning, as well as of other ... the aim of extending the uses of the device ...
... Dengue fever is a viral infection transmitted through the ... patients //never knowing they have been infected. However, in ... tendency triggering the often-fatal Dengue Shock Syndrome. Because some ... the virus from the tropics back to their home ...
... rise in pneumonia, bronchitis and other acute respiratory infections in ... the United Nations health agency is sending antibiotics for thousands ... many more from catching the illnesses. ,“Early ... save lives,” UN spokesman Adrian Edwards told a press briefing ...
... diuretic drugs should not be recommended as a way to ... caused during pregnancy. It is characterized by high blood pressure, ... urine. The high blood pressure can affect the brain, kidneys, ... in the 1960s to women in order to avoid dangerously ...
... of researchers has constructed a model that predicts how ... by airliners. ,The study, "Modeling the Worldwide ... appears in the January issue of the journal PLoS ... the world's largest-scale epidemic simulation of its kind. ...
Cached Medicine News:Health News:Cat Owners at Risk of Bird Flu 2Health News:A Patented Device for Rapid Diagnosis of Diseases 2Health News:Europeans Developing First-Ever Dengue Fever Vaccine 2Health News:UN Sends Medicine to Afghanistan 2Health News:Avoid Diuretic Pills During Pregnancy 2Health News:Scientists Assess Risk of Flu Pandemic Spread Via Global Airlines 2Health News:Scientists Assess Risk of Flu Pandemic Spread Via Global Airlines 3
(Date:1/15/2014)... , Jan. 15, 2014 ... research report is available in its ... Markets and Technologies for Advanced Drug ... of Administration ...
(Date:1/14/2014)... HeartWare International, Inc . (NASDAQ: HTWR ... support technologies that are revolutionizing the treatment of advanced ... the fourth quarter of 2013 will be approximately $53 ... million. "Our full-year revenue growth of 87% ...
(Date:1/14/2014)... BEVERLY HILLS, Calif. , Jan. 14, 2014 The Brandeis ... Los Angeles a premier and affordable laser tattoo ... treatment special. Dr. Brandeis, focus is in providing high quality cosmetic ... to all patients. " Southern California ...
Breaking Medicine Technology:Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 2Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 3Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 4Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 5Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 6Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 7Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 8Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 9Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 10Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 11Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 12Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 13Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 14Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 15Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 16HeartWare International Announces Preliminary Fourth Quarter 2013 Revenues 2HeartWare International Announces Preliminary Fourth Quarter 2013 Revenues 3HeartWare International Announces Preliminary Fourth Quarter 2013 Revenues 4Beverly Hills Physician Features Tattoo Removal with the Astanza Duality Laser, Offers $99 Special 2
... the Horizon 2" Special Session, ROCKVILLE, Md., ... a clinical-stage pharmaceutical company developing,therapeutics for the treatment ... present preclinical data for its product candidates,ENMD-2076, MKC-1, ... EntreMed,scientists and collaborators during the American Association for ...
... to improve ... management of risk for infection, BOSTON, April 10 ... lung transplantation at the,University of Pittsburgh Medical Center (UPMC) has ... with,microbial analysis of bronchoalveolar (BAL) fluids in immunosuppressed,patients, can help ...
Cached Medicine Technology:EntreMed to Highlight ENMD-2076 Kinase Inhibitor at 2008 AACR Annual Meeting 2EntreMed to Highlight ENMD-2076 Kinase Inhibitor at 2008 AACR Annual Meeting 3Prospective Microbial Analysis of Bronchoalveolar Lavage Fluids with Immune Function Testing Can Distinguish Between Fungal Colonization and Fungal Disease In Lung Transplant Recipients 2Prospective Microbial Analysis of Bronchoalveolar Lavage Fluids with Immune Function Testing Can Distinguish Between Fungal Colonization and Fungal Disease In Lung Transplant Recipients 3
A full function instrument at an economical price....
... The ophthalmoscope with superior aspherical optics. ... by means of the aspherical optical system ... Beta 200 allows you to view the ... retina even with a small pupil. Conventional ...
The world's first automatic computation program analyzes massive amount of measurement data and computes "the most comfortable value" for the patient....
... Rx Master is designed and ... reliable service and give the ... improve procedures. It embodies the ... want most, including accuracy, speed, ...
Medicine Products: