Navigation Links
New FDA program adds to tools to curb opiod abuse in United States
Date:8/1/2012

PHILADELPHIA -- A new risk management plan from the U.S. Food and Drug Administration to help clinicians properly prescribe drugs with addiction potential aims to help reduce the growing epidemic of opioid abuse in the United States. With deaths associated with these drugs, often sold illegally, now reaching toward 14,000 each year including the fatal shootings of two Philadelphia teenagers last week in a house where police found large quantities of Percocet and morphine, prescription drug pads, and more than $100,000 in cash -- the authors of a Viewpoint piece in the new issue of the Journal of the American Medical Association say the new plan represents a promising opportunity to cut the amount of addictive prescription drugs in circulation for sale and abuse.

The authors, medical toxicologists Jeanmarie Perrone, MD, an associate professor of Emergency Medicine in the Perelman School of Medicine at the University of Pennsylvania, and Lewis S. Nelson, MD, a professor of Emergency Medicine at the New York University School of Medicine, highlight the FDA's new Risk Evaluation and Mitigation Strategy (REMS), which seeks to manage and prevent the serious risks of misuse and addiction associated with long-acting and extended-release opioids such as OxyContin.

The plan, adopted in early July, includes requirements for prescriber continuing education and patient counseling. A separate REMS for fentanyl lozenges and nasal sprays has also been implemented, requiring a patient-prescriber agreement outlining the expectations and responsibilities for using the drugs safely.

In addition to rolling out the new REMS in a way that's easy and quick for prescribers to use, the authors support a closer look at evidence associated with the true efficacy and risks associated with using opioids for chronic noncancer pain, which has been a large driver of increased prescriptions for these medications over the past 20 years. They also call for a revision of drug labeling to reflect the latest science about risk-benefit information and the most appropriate uses of the medications, a move that was also urged in a petition to the FDA signed by physicians and public health activists last week. The authors also suggest the creation of a REMS for short-acting opioids, which studies have shown is widely associated with nonmedical use.

"There is no single magic bullet for addressing opioid abuse in the community, which has become an enormous public health problem. But we are optimistic that this is the first of several steps needed to enhance safe prescribing of these powerful drugs," Perrone says.

Dr. Perrone is available to discuss opioid abuse and misuse, proper prescribing methods and indications for use of these drugs, and efforts to curtail the epidemic of opioid abuse and deaths, such as REMS and state-run prescription drug monitoring programs.


'/>"/>
Contact: Holly Auer
holly.auer@uphs.upenn.edu
215-349-5659
University of Pennsylvania School of Medicine
Source:Eurekalert

Related medicine news :

1. Screening programs detect cases of undiagnosed rheumatic heart disease in low-resource countries
2. Ivy Neurological Sciences Internship program funded at TGen
3. Brief training program improves resident physicians empathy with patients
4. Southeast program to fight diabetes awarded nearly $10 million by HHS
5. Program to coordinate regional systems to speed heart attack care
6. Fewer prostate cancer surgery complications found in teaching hospitals with fellowship programs
7. UC San Diego Superfund Research Program receives $15 million grant renewal
8. UCLA launches first face transplantation program in western US
9. Rutgers leads effort to replicate care management programs in 4 U.S. cities
10. Steffi Nossen School of Dance Gears Up for Summer with Exciting Programming for All Ages
11. Coronary rehabilitation programs in Europe are underused
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... June 25, 2016 , ... ... issues and applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, at the ... several important health care topics including advance care planning, healthcare costs and patient ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern Californian, Dr. Omkar Marathe ... from the David Geffen School of Medicine at UCLA. He trained in Internal Medicine ... his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had the ...
(Date:6/24/2016)... ... ... Those who have experienced traumatic events may suffer from a complex set of ... or alcohol abuse, as a coping mechanism. To avoid this pain and suffering, Serenity ... event. , Trauma sufferers tend to feel a range of emotions, from depression, guilt, ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... now offering micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive experience with ... Damon brackets , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Haute Beauty Network, ... M. Weintraub as a prominent plastic surgeon and the network’s newest partner. ... the most handsome men, look naturally attractive. Plastic surgery should be invisible.” He ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)...   Pulmatrix, Inc ., (NASDAQ: PULM ... announced today that it was added to the Russell ... comprehensive set of U.S. and global equity indexes on ... milestone for Pulmatrix," said Chief Executive Officer Robert ... progress in developing drugs for crucial unmet medical needs, ...
(Date:6/23/2016)... Any dentist who has made an implant supported ... Many of them do not even offer this as a ... laboratory costs involved. And those who ARE able to offer ... high cost that the majority of today,s patients would not ... Zadeh , founder of Dental Evolutions Inc. and inventor of ...
(Date:6/23/2016)... 23, 2016 Capricor Therapeutics, ... a biotechnology company focused on the discovery, development ... patient enrollment in its ongoing randomized HOPE-Duchenne clinical ... 50% of its 24-patient target. Capricor expects the ... quarter of 2016, and to report top line ...
Breaking Medicine Technology: