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New Experts Help New England Peptide Combat Global Acetonitrile Shortage; Company Integrating Cost-Effective Chemical Solvent Alternatives
Date:1/9/2009

tides. The global slowdown of the automotive industry, combined with the temporary shuttering of key acetonitrile production plants, has caused a global shortage of the product that could last well into 2009.

Under the direction of Hammer and with the consultation of Hodges, NEP has already started using alternative chemical solvents, including methanol and isopropanol. Hammer noted that the use of these alternative solvents can provide the same level of purity and yield as acetonitrile while not increasing costs. NEP has already begun to utilize alcohol solvents in its production with excellent results and without delays in delivery of peptide products to customers.

"NEP has already purified hundreds of peptides utilizing alcohol solvents in our production without interruption of service to our customers" said Hammer. "In some cases we even see superior performance in difficult separations."

Hammer joined NEP in September from Louisiana State University (LSU), where he was the William A. Pryor Professor of Chemistry. Hammer is the recipient of a dozen major national and international honors and awards, including Lee Irvin Smith Award for High Ability and Leadership in Organic Chemistry. In 2006, his work on peptide analogues for inhibiting amyloid protein aggregation was recognized by Scientific American. Hammer earned his doctoral degree in organic chemistry from the University of Minnesota, where he worked with research advisor George Barany, Ph.D..

Hodges joins the SAB with a 35-year reputation as a peptide research expert. He is currently the Director of the Program in Biomolecular Structure, Professor of Biochemistry and Molecular Genetics at the University of Colorado, Denver, School of Medicine, where he holds the John Stewart Chair in Peptide Chemistry. In 2002, he won the Vincent Du Vigneaud Award from the American Peptide Society for outstanding achievements in peptide research. He also wor
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