Navigation Links
New EPA Rodent Study Finds No Low-Dose BPA Effects on Reproductive Function or Behavior
Date:10/29/2009

ARLINGTON, Va., Oct. 29 /PRNewswire-USNewswire/ -- The American Chemistry Council (ACC) today commented on a significant study funded and conducted by EPA and published online yesterday in the journal Toxicological Sciences. In this study, researchers exposed female rodents to both BPA and ethinyl estradiol (EE2)in utero in a wide range of doses to look for effects.

Quotes below may be attributed to Steven G. Hentges, Ph.D., ACC's Polycarbonate/BPA Global Group:

"This new rodent study, funded and conducted by EPA, finds that low-dose exposures of bisphenol A (BPA) showed no effects on the range of reproductive functions and behavioral activities measured. Well-conducted, peer-reviewed studies such as this provide the basis for reasoned government assessments and regulatory decisions.

"Eleven regulatory agencies from around the world have concluded that science supports the safety of BPA for people of all ages in its current uses. The results of this new study provide further strong support for those conclusions. Plastics made with BPA contribute to the safety and convenience of everyday life because of their durability, clarity and shatter-resistance. Can liners made with BPA are essential components to protecting the safety of packaged foods and preserving products from spoilage and contamination.

"These areas of scientific interest were identified as needing further research in a 2008 report on BPA from the National Toxicology Program. This EPA-funded, well-conducted study is a significant development in better understanding the safety of BPA. Sound scientific review must be the foundation of decisions concerning the government's current and future regulatory process, as chemical management reform is considered."

Background on the study

The study conclusion states: "The lack of effect of BPA on female and male rat offspring after oral exposure to low doses in our studies is consistent with the lack of adverse effects on growth, vaginal opening, fertility and fecundity of low doses of BPA in several other robust, well designed, properly analyzed multigenerational studies (Cagen, et al.,1999; Ema, et al., 2001; Tinwell, et al., 2002; Tyl, et al., 2002)."

The study titled "In Utero and Lactational Exposure to Bisphenol A, in contrast to Ethinyl Estradiol, Does not Alter Sexually Dimorphic Behavior, Puberty, Fertility and Anatomy of Female LE Rats," (Bryce C. Ryan, et al.). In the study, researchers fed BPA to female rats during pregnancy and lactation at dosage levels approximately 40 to 4,000 times above estimated median human consumption, and the female offspring were studied for effects on behavior and reproductive function. No effects from exposure to BPA were found in this study. In contrast, the well-known estrogen ethinyl estradiol (EE2) had significant effects on the rodents, demonstrating the sensitivity of the study and the validity of the results for BPA.

www.americanchemistry.com/newsroom

The American Chemistry Council (ACC) represents the leading companies engaged in the business of chemistry. ACC members apply the science of chemistry to make innovative products and services that make people's lives better, healthier and safer. ACC is committed to improved environmental, health and safety performance through Responsible Care(R), common sense advocacy designed to address major public policy issues, and health and environmental research and product testing. The business of chemistry is a $689 billion enterprise and a key element of the nation's economy. It is one of the nation's largest exporters, accounting for ten cents out of every dollar in U.S. exports.

SOURCE American Chemistry Council


'/>"/>
SOURCE American Chemistry Council
Copyright©2009 PR Newswire.
All rights reserved

Related medicine news :

1. New Report Finds U.S. Cities More Vulnerable Than Ever to Rodent Infestation
2. Stress hormone impacts memory, learning in diabetic rodents
3. Rodent study finds artificial butter chemical harmful to lungs
4. Improved rodent trials can speed cancer drug development
5. Turmeric extract suppresses fat tissue growth in rodent models
6. New Scientific Evidence Suggests Humans Resistant to Phthalate Effect on Lab Rodents
7. Penn study finds pro-death proteins required to regulate healthy immune function
8. New study shows promise in reducing surgical risks associated with surgical bleeding
9. Study, meta-analysis examine factors associated with death from heatstroke
10. Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinsons symptoms
11. Study says COPD testing is not measuring up
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/5/2016)... ... 2016 , ... Nepenthe Laboratory Services (NLS), a premier drug monitoring and toxicology ... food item donations for Food for Lane County, and to help support awareness for ... of the assembly was to create an exciting atmosphere for the kids at Riverbend ...
(Date:5/5/2016)... ... May 05, 2016 , ... BloodHub, ... blood and service orders. Blood suppliers and their hospitals use BloodHub for ... serves 13,000 active users across 2,100 hospitals who use our platform to processes ...
(Date:5/4/2016)... (PRWEB) , ... May 05, 2016 , ... “Less than ... Jeffers, Little City Executive Director. “As one of ten non-profit organizations to participate and ... Points of Light. The ultimate benefit is that for every $1 we invest in ...
(Date:5/4/2016)... (PRWEB) , ... May 04, 2016 , ... ... million in grants to identify, fund and implement ideas aimed at improving care ... Medicaid. , “Part of our vision for Trinity Health is to drive ...
(Date:5/4/2016)... Charlotte, NC (PRWEB) , ... May 04, 2016 ... ... platform for sleep wellness and sleep disorder management, today announced it has secured ... World Innovation Lab (WiL) and existing investors. The investment will be used by ...
Breaking Medicine News(10 mins):
(Date:5/4/2016)... May 4, 2016 According to market ... and Demand Forecast to 2022 - Industry Insights by Slice ... Center and Others)" by P&S Market Research, the global ... 2015, and it is expected to grow at a CAGR ... slice type segment is expected to witness the faster growth, ...
(Date:5/4/2016)... , May 4, 2016 ... of the  "Global Acute Ischemic Stroke Market ... to their offering.       (Logo: ... Global Acute Ischemic Stroke Market and Competitive ... Acute Ischemic Stroke pipeline products, Acute Ischemic ...
(Date:5/3/2016)... KANSAS CITY, Mo. , May 3, 2016 ... of Kansas Medical Center,s Institute for Advancing Medical ... develop and commercialize new drugs, diagnostics and medical ... organizations provides BioNovus Innovations with rights to license, ... "This partnership ...
Breaking Medicine Technology: