Navigation Links
New EPA Rodent Study Finds No Low-Dose BPA Effects on Reproductive Function or Behavior
Date:10/29/2009

ARLINGTON, Va., Oct. 29 /PRNewswire-USNewswire/ -- The American Chemistry Council (ACC) today commented on a significant study funded and conducted by EPA and published online yesterday in the journal Toxicological Sciences. In this study, researchers exposed female rodents to both BPA and ethinyl estradiol (EE2)in utero in a wide range of doses to look for effects.

Quotes below may be attributed to Steven G. Hentges, Ph.D., ACC's Polycarbonate/BPA Global Group:

"This new rodent study, funded and conducted by EPA, finds that low-dose exposures of bisphenol A (BPA) showed no effects on the range of reproductive functions and behavioral activities measured. Well-conducted, peer-reviewed studies such as this provide the basis for reasoned government assessments and regulatory decisions.

"Eleven regulatory agencies from around the world have concluded that science supports the safety of BPA for people of all ages in its current uses. The results of this new study provide further strong support for those conclusions. Plastics made with BPA contribute to the safety and convenience of everyday life because of their durability, clarity and shatter-resistance. Can liners made with BPA are essential components to protecting the safety of packaged foods and preserving products from spoilage and contamination.

"These areas of scientific interest were identified as needing further research in a 2008 report on BPA from the National Toxicology Program. This EPA-funded, well-conducted study is a significant development in better understanding the safety of BPA. Sound scientific review must be the foundation of decisions concerning the government's current and future regulatory process, as chemical management reform is considered."

Background on the study

The study conclusion states: "The lack of effect of BPA on female and male rat offspring after oral exposure to low doses in our studies is consistent with the lack of adverse effects on growth, vaginal opening, fertility and fecundity of low doses of BPA in several other robust, well designed, properly analyzed multigenerational studies (Cagen, et al.,1999; Ema, et al., 2001; Tinwell, et al., 2002; Tyl, et al., 2002)."

The study titled "In Utero and Lactational Exposure to Bisphenol A, in contrast to Ethinyl Estradiol, Does not Alter Sexually Dimorphic Behavior, Puberty, Fertility and Anatomy of Female LE Rats," (Bryce C. Ryan, et al.). In the study, researchers fed BPA to female rats during pregnancy and lactation at dosage levels approximately 40 to 4,000 times above estimated median human consumption, and the female offspring were studied for effects on behavior and reproductive function. No effects from exposure to BPA were found in this study. In contrast, the well-known estrogen ethinyl estradiol (EE2) had significant effects on the rodents, demonstrating the sensitivity of the study and the validity of the results for BPA.

www.americanchemistry.com/newsroom

The American Chemistry Council (ACC) represents the leading companies engaged in the business of chemistry. ACC members apply the science of chemistry to make innovative products and services that make people's lives better, healthier and safer. ACC is committed to improved environmental, health and safety performance through Responsible Care(R), common sense advocacy designed to address major public policy issues, and health and environmental research and product testing. The business of chemistry is a $689 billion enterprise and a key element of the nation's economy. It is one of the nation's largest exporters, accounting for ten cents out of every dollar in U.S. exports.

SOURCE American Chemistry Council


'/>"/>
SOURCE American Chemistry Council
Copyright©2009 PR Newswire.
All rights reserved

Related medicine news :

1. New Report Finds U.S. Cities More Vulnerable Than Ever to Rodent Infestation
2. Stress hormone impacts memory, learning in diabetic rodents
3. Rodent study finds artificial butter chemical harmful to lungs
4. Improved rodent trials can speed cancer drug development
5. Turmeric extract suppresses fat tissue growth in rodent models
6. New Scientific Evidence Suggests Humans Resistant to Phthalate Effect on Lab Rodents
7. Penn study finds pro-death proteins required to regulate healthy immune function
8. New study shows promise in reducing surgical risks associated with surgical bleeding
9. Study, meta-analysis examine factors associated with death from heatstroke
10. Study suggests loss of 2 types of neurons -- not just 1 -- triggers Parkinsons symptoms
11. Study says COPD testing is not measuring up
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... Brooklyn, NY (PRWEB) , ... June 27, 2016 ... ... is using cutting edge technology to revolutionize the emergency ambulance transport experience for ... Many are aware of how Uber has disrupted the taxi industry through the ...
(Date:6/26/2016)... ... June 26, 2016 , ... PawPaws brand pet ... product that was developed to enhance the health of felines. The formula is all-natural ... two main herbs in the PawPaws Cat Kidney Support Supplement Soft Chews ...
(Date:6/25/2016)... ... , ... The temporary closing of Bruton Memorial Library on June 21 due to a possible ... often overlooked aspect of head lice: the parasite’s ability to live away from a human ... but a necessary one in the event that lice have simply gotten out of control. ...
(Date:6/25/2016)... , ... June 25, 2016 , ... On Friday, June ... a Bronze Wellness at Work award to iHire in recognition of their exemplary accomplishments ... of the 7th annual Maryland Workplace Health & Wellness Symposium at the BWI Marriott ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Marcy was in a crisis. Her son James, ... out at his family verbally and physically. , “When something upset him, he couldn’t control ... use it. He would throw rocks at my other children and say he was going ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... Tenn. , June 24, 2016  Arkis ... providing less invasive and more durable cerebrospinal fluid ... in funding.  The Series-A funding is led by ... Lighthouse Fund, and other private investors.  Arkis, new ... neurosurgical instrumentation and the market release of its ...
(Date:6/23/2016)... , June 23, 2016 ... "Pharmaceutical Excipients Market by Type (Organic Chemical (Sugar, ... Formulation (Oral, Topical, Coating, Parenteral) - Global Forecast to ... The global pharmaceutical excipients market ... at a CAGR of 6.1% in the forecast period ...
(Date:6/23/2016)... , June 23, 2016 ... CAPR ), a biotechnology company focused on the ... announced that patient enrollment in its ongoing randomized ... has exceeded 50% of its 24-patient target. Capricor ... the third quarter of 2016, and to report ...
Breaking Medicine Technology: