Navigation Links
New Drug Slows Advanced Kidney Cancer
Date:1/26/2010

Pazopanib may double time to disease progression, study finds

TUESDAY, Jan. 26 (HealthDay News) -- Treating advanced kidney cancer patients with the drug pazopanib (Votrient) slowed their disease progression by 54 percent, a new study has found.

The phase 3 study included 233 patients with previously untreated kidney cancer (also known as renal cell carcinoma) that was locally advanced or had spread, and 202 patients with renal cell carcinoma who had previously been treated with cytokine therapy (interferon or interleukin). The patients were randomly assigned to take pazopanib tablets (290 patients) or a placebo drug (145 patients).

In the pazopanib group, it took an average 9.2 months for the cancer to progress, vs. an average 4.2 months in the placebo group. The difference was greatest in previously untreated patients (11.1 months for the pazopanib group and 2.8 months for the placebo group), but also was found among patients previously treated with cytokines (7.4 months in the pazopanib group vs. 4.2 months in placebo group).

Common side effects of pazopanib treatment included diarrhea (52 percent), high blood pressure (40 percent), hair color changes (38 percent), nausea (26 percent), weight loss (22 percent) and vomiting (21 percent).

The data from this study, published online Jan. 25 in the Journal of Clinical Oncology, was used by the U.S. Food and Drug Administration to approve pazopanib in October 2009 for the treatment of advanced renal cell carcinoma.

Pazopanib inhibits the development of blood vessels that tumors need to grow and spread.

"Advanced renal cell carcinoma remains a challenging disease, but treatment has improved with the introduction of new targeted therapies over the past year -- including pazopanib, which targets multiple pathways within cancer cells," study author Dr. Cora Sternberg, chief of the medical oncology department at the San Camillo and For
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. Genetic Variant Slows AIDS Progression
2. Wistar researchers show targeting normal cells in tumors slows growth
3. Drinking coffee slows progression of liver disease in chronic hepatitis C sufferers
4. Prime Therapeutics 2009 Drug Trend Insights Shows Drug Spending Slows to Lowest Rate on Record
5. Vaccine slows progression of skeletal muscle disorder
6. Male Cosmetic Surgery Slows Down While Female Cosmetic Surgery Advances
7. AIDS Drug Slows Spread of Deadly Childhood Brain Cancer
8. Chondroitin slows progression and relieves symptoms of knee osteoarthritis
9. Old gastrointestinal drug slows aging, McGill researchers say
10. Adult-onset diabetes slows mental functioning in several ways, with deficits appearing early
11. Vitamin K Slows Insulin Resistance in Older Men
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/1/2015)... Islands, BWI (PRWEB) May 02, 2015 ... It is http://www.thevenetiangracebay.com , and it is ... incorporates the stunning white and attractive turquoise hues of ... of Google, sixty seven percent of leisure travelers used ... showed that smartphones were used in the planning and ...
(Date:5/1/2015)... 01, 2015 Royal River Natural Foods, ... reports on a new study that found two natural ... and improved physical function as well as standard drug ... of the knee. , The report is part of ... Well Being® ,” which Royal River Natural Foods publishes ...
(Date:5/1/2015)... Washington, DC (PRWEB) May 01, 2015 It’s ... Senate and House introducing proposals to expand federal support for ... 22 years that ATA has been working with Congress,” said ... “These actions signify how the nation is poised to embrace ... This is one more step in fulfilling ATA’s mission to ...
(Date:5/1/2015)... Yorba Linda, CA (PRWEB) May 01, 2015 ... of our genetic makeup and the interplay of genes ... Keeping up with developments can be daunting. , LabRoots, ... sciences and clinical diagnostics professionals, will soon host its ... Genomics. , At BioConference Live Genetics and Genomics ...
(Date:5/1/2015)... Denver, Colorado (PRWEB) May 01, 2015 ... United States approaches its 18-month anniversary, many people in ... what’s been achieved. , According the latest annual report ... industry expanded 74 percent in 2014, and reached nearly ... Meanwhile, America’s decades-long love affair with cannabis, combined with ...
Breaking Medicine News(10 mins):Health News:Turks and Caicos Resort, The Venetian on Grace Bay, Launches New Web Presence 2Health News:New Study Finds Nutrients Ease Arthritis Pain, Retailer Reports 2Health News:ATA: Congress Floods the Halls with Telemedicine Proposals 2Health News:Recent Advances in Genetics and Genomics: A BioConference Live 2015 Virtual Event 2Health News:Recent Advances in Genetics and Genomics: A BioConference Live 2015 Virtual Event 3Health News:Colorado cannabis dispensary owner credits employees for successful “420” retail sales figures 2Health News:Colorado cannabis dispensary owner credits employees for successful “420” retail sales figures 3
... Arrangement with ... ... ASPV ; TSX: ASV) today announced that meeting materials,regarding a special ... Group (SWX: GALN) have been,mailed to Aspreva shareholders and optionholders of ...
... StructuRad to Demonstrate Innovative Radiology Reporting Solutions, ... announces,MacroLive, a macro reporting service, at RSNA 2007 ... INFINITT and RamSoft, will offer,this service as an ... is a subscription service that allows a radiologist ...
... to Finally Announce Second-Line AIDS Treatment Provision on World AIDS ... ... Nov. 22 Bowing to an,increasing need for more effective AIDS treatments ... activists,India,s National AIDS Control Organization (NACO) and Health Minister A.,Ramadoss will announce ...
... Toronto, Canada People with a devastating brain injury ... may still be able to understand other peoples feelings ... Rotman Research Institute at the Baycrest Centre for Aging ... Faculty of Health. , The study, published in the ...
... priorities that will impact on the future treatment of breast ... the disease. Research published in the online open access ... issues highlighted as top priorities. , A team led ... Marsden NHS Foundation Trust, based in London and Surrey, together ...
... on hearts, researchers say , , WEDNESDAY, Nov. 21 (HealthDay ... together to boost death risks from heart disease and ... -- which brings more heat and more ozone -- ... of cardiovascular events. , "Temperature and ozone are strong ...
Cached Medicine News:Health News:Aspreva Sends Materials for Special Meeting to be Held December 17 2Health News:Aspreva Sends Materials for Special Meeting to be Held December 17 3Health News:Aspreva Sends Materials for Special Meeting to be Held December 17 4Health News:StructuRad Launches MacroLive(TM) with INFINITT and RamSoft at RSNA 2007 2Health News:StructuRad Launches MacroLive(TM) with INFINITT and RamSoft at RSNA 2007 3Health News:NACO Bows to Activists' Pressure on AIDS Treatment in India, Says AHF 2Health News:NACO Bows to Activists' Pressure on AIDS Treatment in India, Says AHF 3Health News:People with rare type of memory loss still sensitive to others, study shows 2Health News:People with rare type of memory loss still sensitive to others, study shows 3Health News:Found in translation: Prioritizing research questions in breast cancer 2Health News:Global Warming May Trigger Rise in Heart Deaths 2Health News:Global Warming May Trigger Rise in Heart Deaths 3
(Date:5/1/2015)... N.J. , May 1, 2015 /PRNewswire/ ... has expanded its current therapeutic focus beyond ... other serious psychiatric disorders. Braeburn has acquired ... (or second-generation) antipsychotic risperidone for treatment of ... acquisition Braeburn acquires global rights to other ...
(Date:5/1/2015)... 2015 Semler Scientific, Inc. (Nasdaq: SMLR ... manufactures and markets products that assist healthcare providers in ... results for the first quarter ended March 31, 2015. ... Semler reported continued progress with year over year growth ... of 14%," said Doug Murphy-Chutorian , M.D., chief ...
(Date:4/30/2015)... , April 30, 2015 /PRNewswire/ - Pivotal ... pharmaceutical company with a focus on Omega-3 therapies ... its operational highlights and financial results for the ... amounts referenced herein are in Canadian dollars unless ... have been significant, with the right strategic partners ...
Breaking Medicine Technology:Braeburn Pharmaceuticals expands pipeline to include two schizophrenia treatments 2Braeburn Pharmaceuticals expands pipeline to include two schizophrenia treatments 3Braeburn Pharmaceuticals expands pipeline to include two schizophrenia treatments 4Semler Reports First Quarter 2015 Financial Results 2Semler Reports First Quarter 2015 Financial Results 3Semler Reports First Quarter 2015 Financial Results 4Semler Reports First Quarter 2015 Financial Results 5Pivotal Therapeutics Announces 2014 Financial Results 2Pivotal Therapeutics Announces 2014 Financial Results 3Pivotal Therapeutics Announces 2014 Financial Results 4Pivotal Therapeutics Announces 2014 Financial Results 5Pivotal Therapeutics Announces 2014 Financial Results 6
... NEW YORK, Jan. 25, 2011 Reportlinker.com announces ... in its catalogue: Future Technological ... Market through 2018 http://www.reportlinker.com/p0365289/Future-Technological-Breakthroughs-And-Their-Impact-on-the-US-Diagnostics-Market-through-2018.html ... will be marked by significant technological developments in ...
... Angelini Labopharm, LLC, today confirmed Mary ... Senior Vice President, Sales and Marketing for Labopharm Inc. ... USA, Inc., Ms. Heino,s primary focus will be to ... of OLEPTRO™, as well as to explore opportunities for ...
Cached Medicine Technology:Reportlinker Adds Future Technological Breakthroughs and Their Impact on the US Diagnostics Market Through 2018 2Angelini Labopharm Confirms Appointment of Mary Anne Heino as President 2Angelini Labopharm Confirms Appointment of Mary Anne Heino as President 3
The Clark Socket fits all American-made tables with standard 3/8"W x 1 1/8" H siderails. Fits round mounting posts up to 11/16" in diameter....
Inquire...
Stainless steel construction to withstand sterilization modalities (EtO, Steris, and Sterrad)...
Stainless steel construction to withstand sterilization modalities (autoclave, EtO, Steris®, and Sterrad®) Fully autoclavable, with both distal and proximal ends uniquely soldered for longe...
Medicine Products: