Navigation Links
New Drug Regimens May Slow Advanced Breast Cancer
Date:12/5/2012

ce they haven't undergone peer review for publication in a medical journal.

In a separate study reported at the meeting, researchers found that doubling the dose of an existing breast cancer drug, Faslodex (fulvestrant), lengthened women's lives by a few months.

Like the other trial, this one focused on older women with advanced ER-positive cancer. Faslodex is an injected form of hormonal therapy that works by blocking the effects of estrogen on breast cancer cells; it's given to postmenopausal women whose cancer has worsened despite anti-estrogen therapies such as tamoxifen.

Among more than 700 women in the trial, those randomly assigned to a 500-milligram dose of Faslodex typically lived about four months longer: 26 months versus 22 months among women given the standard 250-milligram dose.

The higher dose extended lives without increasing side effects, said the researchers, led by Dr. Angelo Di Leo, head of medical oncology at the Hospital of Prato in Italy.

Faslodex commonly causes side effects such as nausea, vomiting, diarrhea, headaches and hot flashes, and occasionally more serious problems, such as blood clots. In this trial, between 1 percent and 2 percent of women in each group had a serious side effect attributable to the medication.

The trial was sponsored by AstraZeneca Pharmaceuticals, which makes Faslodex.

The higher Faslodex dose has already become the "standard of care," based on earlier findings from the trial, said Dr. Kimberly Blackwell, director of the Duke Breast Cancer Clinic and a professor of medicine at Duke University School of Medicine.

Blackwell, who was not involved in either new study, was more excited about the experimental Pfizer drug.

"We always want to be cautious about a trial that involves fewer than 200 patients," Blackwell said. But, she added, "if this is confirmed in the Phase 3 trial, it could have a big impact on how we treat patients."

What is new about the drug
'/>"/>

Copyright©2012 ScoutNews,LLC.
All rights reserved

Page: 1 2 3

Related medicine news :

1. NIH to test maraviroc-based drug regimens for HIV prevention
2. Experimental Gel May Help Those With Advanced Parkinsons
3. Advanced genetic screening method may speed vaccine development
4. Advanced Prostate Cancer Drug May Help at Earlier Stage
5. Obese More Likely to Be Diagnosed With Advanced Thyroid Cancer
6. GW researchers discover biomarker for advanced bile duct fibrosis and bile duct cancer
7. San Francisco’s Advanced Male Medical Center Announces Discount, Discusses Erectile Dysfunction
8. Advanced Osteoarthritis Of The Knee Is Now Being Treated With Regenerative Medicine At The Center For Regenerative Medicine
9. Ecig Advanced Sponsors Lexington's First Annual Vaping Event
10. Lack of insurance linked to advanced stage cervical cancer
11. Clinical trial seeks to cure advanced Crohns disease using bone marrow transplant
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2014)... A recent University College London (UCL) ... the dental community disagrees on the best way to ... of dental advice suggested that some six different tooth-brushing ... more popular than the rest. , “The easiest ... floss your teeth regularly,” said Dr. Alexandre-Amir Aalam, DDS, ...
(Date:8/27/2014)... "It can be quite difficult to wipe ... an inventor from Lehigh Acres, Fla.," so I designed ... hygienic task." He then created a prototype of his ... user to wipe and clean the behind thoroughly after ... as well as prevents direct contact with waste or ...
(Date:8/27/2014)... (PRWEB) August 27, 2014 Neil Haley, the ... Vimillionaire GJ Reynolds to find out about the importance of ... founding member in the company ViSalus and is now a ... Media. He has written a book titled "The Playful and ... the Dale Brown Challenge by working out for over 1000 ...
(Date:8/27/2014)... 2014 AAPC ( http://www.aapc.com ), ... is pleased to announce the Beta release of ... specifically designed for the healthcare industry. , Healthcare ... help address the primary challenges facing the industry—unqualified ... CareerHealth.com . , CareerHealth.com offers ...
(Date:8/27/2014)... August 27, 2014 IntelliSoft Group, LLC, ... management software, will unveil IntelliCred, IntelliApp and ... of Medical Staff Services (NHAMSS) Annual Conference on September ... in Bedford, NH. , Notable improvements available in ... , Contract Linking: A new Contract Connection ...
Breaking Medicine News(10 mins):Health News:Americans Confused About How to Brush Teeth 2Health News:InventHelp Client's Device Helps a User Wipe Thoroughly After Going to the Bathroom (HLW-1300) 2Health News:Vi Millioniare GJ Reynolds Discusses The Importance of Capacity to Grow a Business on the Simply G Radio Show, a Division of the Simply G Media Network 2Health News:Vi Millioniare GJ Reynolds Discusses The Importance of Capacity to Grow a Business on the Simply G Radio Show, a Division of the Simply G Media Network 3Health News:AAPC Responds to Healthcare Workforce Challenges with CareerHealth.com 2Health News:AAPC Responds to Healthcare Workforce Challenges with CareerHealth.com 3Health News:IntelliSoft Group to Unveil Version 14.2 of IntelliCred, IntelliApp and IntelliContract at the New Hampshire Association of Medical Staff Services Annual Conference 2
... , Montreal, May 28, 2009 Sipping wine, beer ... risk of binge drinking, particularly among young men, according to ... Researchers from the Universit de Montral and the University of ... that frequent alcohol consumption can lead to binge drinking among ...
... package testing services firm specializing in medical device package testing, will be ... will help kick off the conference with a powerful presentation by Scotty ... ... -- DDL , the leading package testing services firm specializing in ...
... the Building Owners and Managers Association (BOMA) Southwest ... HeartSine Technologies announced the donation of thirteen HeartSine ... associations of the BOMA Southwest Region. These ... Oklahoma. Because one American dies approximately every two ...
... Early Helps Identify Developmental Delays and Promote GrowthNEW ORLEANS, ... 10:30am - 11:30am , at 1315 Jefferson ... will "Reach Out and Read " with Louisiana,s ... childhood literacy program. In this initiative, pediatricians encourage parents ...
... 28 Aventis Pharmaceutical Inc., a wholly owned subsidiary of ... $95.5 million to settle allegations that it violated the False ... its Medicaid Drug Rebate obligations, the Justice Department announced today. ... The settlement resolves allegations that between 1995 ...
... YORK, May 28 Kyowa Hakko U.S.A., Inc. (Kyowa ... Bio Co., Ltd., (Kyowa), has announced it has completed ... brain health ingredient Cognizin(R) Citicoline. Cognizin(R) is a branded ... cell of the body. Citicoline provides an essential ...
Cached Medicine News:Health News:Daily alcohol intake can lead to binge drinking 2Health News:DDL, Leader in Medical Device Package, Product and Material Testing, will be Presenting at This Year's MD&M Show in New York 2Health News:HeartSafe and HeartSine Announce AED Donation Program to Local BOMA Associations 2Health News:Ochsner Introduces Literacy Program to Promote Healthy Minds 2Health News:Aventis Pharmaceutical to Pay U.S. $95.5 Million to Settle False Claims Act Allegations 2Health News:Kyowa Hakko USA Announces GRAS Self-Affirmation for Novel Brain Health Ingredient Cognizin(R) Citicoline 2
(Date:8/26/2014)...  Actavis plc (NYSE: ACT ), a leading ... , CEO and President of Actavis, will provide an overview ... Global Healthcare Conference 2014 in New York, NY ... The presentation will take place on Tuesday, September 9, ... New York, 109 East 42 nd Street, ...
(Date:8/26/2014)... Aug. 26, 2014 Global design and architecture firm NBBJ announced ... China . Principal Rudy Widjaja will lead planning ... he will draw on his experience with healthcare clients in ... the United States , as well as the firm,s global network ... China healthcare practice comes at a time when the scope ...
(Date:8/26/2014)... 2014 Equashield ( www.equashield.com ), ... for hazardous drugs, announced today it has appointed a ... around the United States . The ... nurses, awareness of issues around occupational exposure to hazardous ... systems for hazardous drug transfer. "As a ...
Breaking Medicine Technology:Actavis to Present at Morgan Stanley Global Healthcare Conference 2014 2Leading Architectural Design Firm NBBJ Launches Healthcare Practice in China 2Leading Architectural Design Firm NBBJ Launches Healthcare Practice in China 3Leading Architectural Design Firm NBBJ Launches Healthcare Practice in China 4Leading Architectural Design Firm NBBJ Launches Healthcare Practice in China 5Equashield Appoints Nurse Advisory Council 2Equashield Appoints Nurse Advisory Council 3Equashield Appoints Nurse Advisory Council 4
... ... International, an independent nonprofit research and development institute, has received two ... the National Institutes of Health (NIH), to develop a stationary X-ray ... is intended to improve three-dimensional imaging technology, which will make it ...
... Ad, " This is Medicare and America at ... WASHINGTON, Dec. 9 The SCOOTER Store today launched a ... and cost savings associated with Medicare,s Power Mobility Benefit, which ... to receive power wheelchairs. , With budget cuts likely in ...
Cached Medicine Technology:SRI International Receives National Institutes of Health Grants to Develop Improved Tomographic Imaging Technology 2SRI International Receives National Institutes of Health Grants to Develop Improved Tomographic Imaging Technology 3The SCOOTER Store Launches New Advertising Highlighting the Value and Cost Savings From Medicare's Power Mobility Benefit 2
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: