Navigation Links
New Drug May Strengthen Women's Bones
Date:10/27/2008

In study, denosumab outperformed a standard ,,osteoporosis therapy

MONDAY, Oct. 27 (HealthDay News) -- The drug denosumab can boost bone mass in postmenopausal women, according to a study that followed almost 1,200 women, average age 64, with low bone mass for more than one year.

Denosumab inhibits the activation of bone-resorbing cells called osteoclasts.

The women were randomly assigned to receive either a 60 milligram injection of denosumab every six months plus a weekly oral placebo, or an injection of placebo every six months and 70 milligrams of alendronate orally each week. Alendronate (brand name Fosamax) is commonly used in the prevention and treatment of osteoporosis in postmenopausal women.

The women also took at least 500 milligrams of calcium and at least 400 milligrams of vitamin D daily.

At the end of the study, more of the women who received denosumab had gained at least 3 percent of bone mass at the hip and lumbar spine than those who took alendronate.

In addition, blood and urine tests showed that denosumab suppressed markers of bone turnover. This suggests the drug achieved effective suppression of bone resorption, the researchers said.

The study is to be presented Oct. 29 at the annual scientific meeting of the American College of Rheumatology (ACR), in San Francisco.

"The fact that bone density changes were greater than the most commonly used antiresorptive agent, alendronate, shows that denosumab is an effective agent," lead investigator Dr. Chad Deal, head of the Center for Osteoporosis and Metabolic Bone Disease at the Cleveland Clinic, said in an ACR news release.

He added that patients should talk to their rheumatologists to determine the best course of treatment.

More information

The U.S. National Institute of Arthritis and Musculoskeletal and Skin Diseases has more about bone health.



-- Robert Preidt



SOURCE: American College of Rheumatology, news release, Oct. 25, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Global Intelligence Alliance Strengthens Group Organization and Adds Local Presence, Merges With Asian, German and Dutch Partner Companies
2. ADA Asks Congress to Strengthen Medicaid Oral Health Programs
3. Celsius Strengthens Board With Prior Rexall Sundown CFO
4. Abbott Fund and the Government of Tanzania Celebrate Milestone in Strengthening Nations Health Care System
5. Cardinal Health Expands Leader(R) Offering To Help Independent Pharmacies Strengthen Patient Relationships, Solidify Role As Local Health Care Experts
6. Partnership Seeks to Strengthen Ethiopian Public Health System
7. NIH grant to strengthen IU and Purdue program to educate physician-scientists
8. The Henry H. Kessler Foundation Appoints New Vice President for Research and Strengthens Relationship With Current Research Luminary
9. Ikaria(R) Strengthens Research & Development Team
10. EMC Strengthens Information Infrastructure for Boston Health Care for the Homeless Program
11. Hero/Beech-Nuts Role as an Innovation Leader Strengthened with New Infant Food Manufacturing Facility
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Drug May Strengthen Women's Bones
(Date:3/28/2017)... ... March 28, 2017 , ... Calibration, qualification, and the ... results and maintaining GMP and USP compliance. In a new webinar from METTLER ... requirements " these requirements are explained. The challenge is to determine how ...
(Date:3/28/2017)... (PRWEB) , ... March 28, 2017 , ... With less ... from acne, access to quality care can be limited while the desire to conquer ... offers customized prescription acne care for every customer online, today released its inaugural survey ...
(Date:3/28/2017)... , ... March 28, 2017 , ... Columbus OH. Dr. ... as one of few medical professionals in the country to sit on the 2017 ... Juvly Aesthetics, in just 2 years Dr. Harper helped propel the clinic from a ...
(Date:3/28/2017)... ... March 28, 2017 , ... Public relations pros work ... a variety of business channels. , While many results are clear, much of PR ... program. , When it comes to measurement, firms should always take an all-inclusive ...
(Date:3/28/2017)... ... ... skin is a common and unwelcomed occurrence in people of all ages, genders and ethnicities. ... the discussion of dealing with excess skin oil. “Oily skin is a challenge to many ... help remove the oily shine while keeping the skin fresh and clean,” says Dr. Au. ...
Breaking Medicine News(10 mins):
(Date:3/28/2017)... Elysium Health joins major pharmaceutical companies to ... Cambridge academic scientists through ... Institute today announces Elysium Health as a partner to the ... collaborative projects with academic researchers in Cambridge ... major research investment outside the U.S. for the ...
(Date:3/27/2017)... Summary This report provides all the information ... interests and activities since 2010. Description The Partnering Deals ... the partnering activity of one of the world,s leading life ... upon purchase to ensure inclusion of the most up to ... be delivered in PDF format within 1 working day of ...
(Date:3/27/2017)... , March 27, 2017  ImMAGE Biotherapeutics (OTCMKTS: ... immunotherapy successfully passed early toxicology and efficacy studies. The ... to target a specific protein, MAGE A, in an ... breast cancer. After 4 weeks of ... to show very little toxicity in a full toxicology ...
Breaking Medicine Technology: