Navigation Links
New Drug May Strengthen Women's Bones
Date:10/27/2008

In study, denosumab outperformed a standard ,,osteoporosis therapy

MONDAY, Oct. 27 (HealthDay News) -- The drug denosumab can boost bone mass in postmenopausal women, according to a study that followed almost 1,200 women, average age 64, with low bone mass for more than one year.

Denosumab inhibits the activation of bone-resorbing cells called osteoclasts.

The women were randomly assigned to receive either a 60 milligram injection of denosumab every six months plus a weekly oral placebo, or an injection of placebo every six months and 70 milligrams of alendronate orally each week. Alendronate (brand name Fosamax) is commonly used in the prevention and treatment of osteoporosis in postmenopausal women.

The women also took at least 500 milligrams of calcium and at least 400 milligrams of vitamin D daily.

At the end of the study, more of the women who received denosumab had gained at least 3 percent of bone mass at the hip and lumbar spine than those who took alendronate.

In addition, blood and urine tests showed that denosumab suppressed markers of bone turnover. This suggests the drug achieved effective suppression of bone resorption, the researchers said.

The study is to be presented Oct. 29 at the annual scientific meeting of the American College of Rheumatology (ACR), in San Francisco.

"The fact that bone density changes were greater than the most commonly used antiresorptive agent, alendronate, shows that denosumab is an effective agent," lead investigator Dr. Chad Deal, head of the Center for Osteoporosis and Metabolic Bone Disease at the Cleveland Clinic, said in an ACR news release.

He added that patients should talk to their rheumatologists to determine the best course of treatment.

More information

The U.S. National Institute of Arthritis and Musculoskeletal and Skin Diseases has more about

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Global Intelligence Alliance Strengthens Group Organization and Adds Local Presence, Merges With Asian, German and Dutch Partner Companies
2. ADA Asks Congress to Strengthen Medicaid Oral Health Programs
3. Celsius Strengthens Board With Prior Rexall Sundown CFO
4. Abbott Fund and the Government of Tanzania Celebrate Milestone in Strengthening Nations Health Care System
5. Cardinal Health Expands Leader(R) Offering To Help Independent Pharmacies Strengthen Patient Relationships, Solidify Role As Local Health Care Experts
6. Partnership Seeks to Strengthen Ethiopian Public Health System
7. NIH grant to strengthen IU and Purdue program to educate physician-scientists
8. The Henry H. Kessler Foundation Appoints New Vice President for Research and Strengthens Relationship With Current Research Luminary
9. Ikaria(R) Strengthens Research & Development Team
10. EMC Strengthens Information Infrastructure for Boston Health Care for the Homeless Program
11. Hero/Beech-Nuts Role as an Innovation Leader Strengthened with New Infant Food Manufacturing Facility
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Drug May Strengthen Women's Bones
(Date:8/20/2014)... (PRWEB) August 20, 2014 BuyCheapTicketsToEvents.com ... a wide selection of tickets to many events. Cheap NHL ... will begin in September. , Hockey fans are enthusiastic about ... obtain tickets for games. Now is the time to acquire ... begin in mere months. There will be a great deal ...
(Date:8/20/2014)... people grow older, they often have difficulty falling asleep ... in the morning. In individuals with Alzheimer,s disease, this ... especially pronounced, often leading to nighttime confusion and wandering. ... Israel Deaconess Medical Center (BIDMC) and the University of ... more fragmented with age. Reported online today in the ...
(Date:8/20/2014)... Mixberry Media announced today its new ... create a new source of revenue. , The innovative ... to a narration of their favorite news and articles ... Users can now multitask: read/write email, drink coffee, ... content. , Mixberry Media’s service converts news ...
(Date:8/20/2014)... August 20, 2014 Riverside Health System ... , who joined its Warsaw Medical Arts team earlier ... in Family Medicine, is accepting new patients. , Dameron, ... Medicine, completed his residency at the Mountain Area Health ... Virginia. , “I really like the rural aspect of ...
(Date:8/19/2014)... 20, 2014 As moms and dads prepare ... to return to the normal routine of dropping their little ... Kristen Yarker, MSc, RD encourages them to use the ... snack time. , Yarker explains, “Kids have small tummies, ... of giving them junk food handouts, use snack time as ...
Breaking Medicine News(10 mins):Health News:2014 NHL Preseason Tickets Are Among Top Selling Seats at Trusted Provider BuyCheapTicketsToEvents.com 2Health News:Research helps explain why elderly have trouble sleeping 2Health News:Research helps explain why elderly have trouble sleeping 3Health News:Mixberry Media, First To Offer Article Voice Narration with Integrated Audio Advertising 2Health News:Riverside Warsaw Medical Arts’ Dr. William Dameron Accepting New Patients 2Health News:Child Nutritionist Kristen Yarker Wants Parents to Rethink Kids’ Snacks This Fall 2Health News:Child Nutritionist Kristen Yarker Wants Parents to Rethink Kids’ Snacks This Fall 3
... FirmsPHILADELPHIA, Jan. 15 /PRNewswire/ -- Michael ... Centocor, Inc., an operating company of Johnson & ... public relations consultancy, Pitch360 Incorporated ( www.pitch360inc.com ). ... issues management consultancy that leverages its vast pharmaceutical ...
... aging causes broken bones to heal slowly, or not at ... Journal of Bone and Mineral Research . The research team ... of treatments designed to "rescue" healing capability lost to aging. ... healing keeps the two sides of a fractured bone from ...
... Enterprises Ltd. ("Beeston") (OTC-BB:BESE) a resource base company ... mineral properties, announced that its Board of Directors ... of its full media campaign. MicroCap Management has ... a launch pad for Beeston,s present and future ...
... Area Treatments Twice as Fast and Improves Patient Treatment ... SLTM ) today announced the launch of ... system for faster, more comfortable body shaping, contouring and ... of traditional Thermage tips, Body Tip 16.0 cuts body ...
... WINSTON-SALEM, N.C., Jan. 15 For consumers, the Internet,offers ... vacations; however,when it comes to finding the best doctor, ... days, there are Web sites that offer ratings on,everyone ... picking,the best restaurants and hotels in town are getting ...
... Outlines Steps Taken to Reduce Expenses in Light ... Mass., Jan. 15 Cynosure, Inc. (NASDAQ: ... of a broad array of light-based aesthetic treatment ... fourth quarter ended December 31, 2008.Cynosure expects to ...
Cached Medicine News:Health News:Former Johnson & Johnson Executive Gives Big Voice to Small Companies 2Health News:Researchers detail how aging undermines bone healing 2Health News:Researchers detail how aging undermines bone healing 3Health News:Researchers detail how aging undermines bone healing 4Health News:Beeston Retains MicroCap Management, LLC as Its Lead Corporate Communications and Broker Relations Firm 2Health News:Beeston Retains MicroCap Management, LLC as Its Lead Corporate Communications and Broker Relations Firm 3Health News:Video: Solta Medical Introduces Advanced Thermage Body Tip 16.0 for Faster Body Shaping and Contouring Treatments 2Health News:Video: Solta Medical Introduces Advanced Thermage Body Tip 16.0 for Faster Body Shaping and Contouring Treatments 3Health News:DrScore.com Says: Know Your Source When Going Online To Review Your Doctor's Rating 2Health News:DrScore.com Says: Know Your Source When Going Online To Review Your Doctor's Rating 3Health News:Cynosure Provides Preliminary Financial Results for the Fourth Quarter of 2008 2Health News:Cynosure Provides Preliminary Financial Results for the Fourth Quarter of 2008 3Health News:Cynosure Provides Preliminary Financial Results for the Fourth Quarter of 2008 4
(Date:8/19/2014)... -- According to Kalorama Information, electronic medical records (EMR) ... in healthcare a reality, and this a factor that ... Recovery and Reinvestment Act, the U.S. government dedicated $20.6 ... will start applying soon for use of paper records.  ... of the EMR industry, EMR 2014: The Market ...
(Date:8/19/2014)... 2014  Cardiva Medical, Inc. announced today that it ... million Series 3 private equity financing and a $12.5 ... will use the proceeds of the Series 3 private ... for its VASCADE® Vascular Closure System in ... in Series 3 private equity financing was a new ...
(Date:8/19/2014)... , Aug. 19, 2014  Regeneron Pharmaceuticals, Inc. (NASDAQ: ... conferences: , Sanofi and Regeneron will host an IR ... on Tuesday, September 2, 2014 , Baird 2014 ... September 3, 2014 , Citi,s 9 th ... Thursday, September 4, 2014 , Morgan Stanley Global ...
Breaking Medicine Technology:Kalorama: EMR Paves the Way for Big Data 2Kalorama: EMR Paves the Way for Big Data 3Cardiva Medical, Inc. Announces Completion of the first two tranches of Series 3 Private Equity Financing and the Closing of a Senior Secured Debt Facility with GE Capital 2
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: