Navigation Links
New Drug Aids Muscle Function in Myasthenia Gravis
Date:8/18/2007

Trial of 16 patients saw 46% improvement in symptoms

FRIDAY, Aug. 17 (HealthDay News) -- A new drug -- oral EN101antisense -- reduced the severity of muscle weakness in patients with myasthenia gravis, researchers report.

Myasthenia gravis (MG), which affects about 20 in 100,000 people, causes fatigue and reduced strength in voluntary muscles. Other symptoms may include double vision, drooping eyelids, difficulty swallowing, or slurred speech.

The small open-label study included 16 MG patients who took daily doses of oral EN101antisense for four days and were monitored for a month. On average, the patients experienced a 46 percent reduction in symptom severity. Side effects included dryness of the eyes and mouth.

The study, published in the Aug. 14 issue of Neurology, was supported by the biotechnology company Ester Neuroscience Ltd.

"This is the first time we've been able to show that antisense is effective and safe when taken orally for a neurological disease," study author Dr. Zohar Argov, of the Hadassah Hebrew University Medical Center in Jerusalem, said in a prepared statement.

Further research is planned to study the effects of the drug over a longer period of time.

Antisense is a synthetic, short segment DNA that blocks production of specific proteins. Oral EN101antisense inhibits production of an enzyme called acetylcholine esterase, which plays an important role in the function of the neuromuscular junction, where nerves connect with muscles.

More information

The American Medical Association has more about myasthenia gravis.



-- Robert Preidt



SOURCE: American Academy of Neurology, news release, Aug. 13, 2007


'/>"/>

Copyright©2007 ScoutNews,LLC.

Page: 1

Related medicine news :

1. Mushroom and muscle loss
2. Blood Pressure Drugs maintain muscle strength
3. New treatment for muscle spasms
4. Protein can change worn muscle fibres
5. Stretching the muscles doesnt make them more resilient
6. Protein said to Improve Muscle Loss
7. ‘Protein’ Produced By Overstressed Heart Muscle a Strong Indicator Of Heart Diseae
8. Regeneration of muscle
9. Protein Found To Improve Muscle Loss
10. Strong Pelvic Muscles Found To Facilitate Childbirth
11. Molecule responsible for muscle repair identified
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2015)... ... 31, 2015 , ... Well-known for its unique pastries and delicious confections, Pastry ... custom designs, making life just a little bit sweeter for newlyweds. A family-owned business, ... who orders one. , The bakery provides a full line of custom wedding cakes. ...
(Date:7/31/2015)... ... , ... As part of their company mission, Dallas pet sitting company ... is essential to the longevity of their business. It is for that reason ... Pet Sitters (NAPPS) annual Presents 4 Pets supply drive. Presents 4 Pets ...
(Date:7/31/2015)... Chicago, IL (PRWEB) , ... July 31, 2015 , ... ... Hope IVF , is in pursuit of a visionary image that goes beyond the ... the UAE, New Hope IVF has reached extraordinary heights with dependable patient support, affordable ...
(Date:7/31/2015)... Maryland (PRWEB) , ... July 31, 2015 , ... ... and marketing research firm, has been recognized in the 2015 Aster Awards national ... a regional healthcare organization serving Ocean City and surrounding communities in Coastal Maryland ...
(Date:7/31/2015)... ... 31, 2015 , ... BioViva USA, Inc. (“BioViva”), a to-clinic gene therapy company ... , BioViva announces it has begun a fundraiser through Maximum Life Foundation (“MaxLife”) to ... a cure. MaxLife will grant 100% of the money raised to BioViva to help ...
Breaking Medicine News(10 mins):Health News:Pastry Palace of Las Vegas Announces It Is Now Offering Custom Wedding Cakes in Las Vegas 2Health News:Dallas-based Park Cities Pet Sitter Selects Non-Profit Animal Welfare Organization “Angie’s Friends” as this Year’s Recipient of their Presents 4 Pets Supply Drive. 2Health News:Dallas-based Park Cities Pet Sitter Selects Non-Profit Animal Welfare Organization “Angie’s Friends” as this Year’s Recipient of their Presents 4 Pets Supply Drive. 3Health News:Dallas-based Park Cities Pet Sitter Selects Non-Profit Animal Welfare Organization “Angie’s Friends” as this Year’s Recipient of their Presents 4 Pets Supply Drive. 4Health News:New Hope IVF Now Offers Most Affordable Assisted Reproductive Treatment in the UAE 2Health News:New Hope IVF Now Offers Most Affordable Assisted Reproductive Treatment in the UAE 3Health News:Mullin/Ashley Associates Wins in the 2015 Aster Awards National Competition for Excellence in Medical Marketing 2Health News:BioViva USA, Inc.’s Alzheimer’s Disease Gene Therapy Human Trial 2Health News:BioViva USA, Inc.’s Alzheimer’s Disease Gene Therapy Human Trial 3
... ... , ... 2010 -- From self-published author Felicia J. Henderson comes a personal tale of despair, survival, ... book that will reach out to those who have experienced life’s trials and never lost ...
... ... volcano Eyjafjallajökull has not only interfered in the air traffic around the globe. ... the important booking season for tourism to Iceland, it has affected the bookings ... only seen few requests on holiday offers since the eruption had started and ...
... Calif.) Extremely obese children have a 40 percent ... who are moderately obese have a 30 percent higher ... to a Kaiser Permanente study published online in the ... large population-based study establishes an association between obesity and ...
... ... three dental programs in the nation to receive the “Best Practice” award from Safety Net ... have translated into positive improvements for the communities they serve. , ... (Vocus) July 8, 2010 -- St. Elizabeth’s ...
... ... Patient Care , ... NY (Vocus) July 8, 2010 -- As nursing assumes an increasingly prominent role in the ... announced today it will soon require newly hired nurses to have a Bachelor of Nursing ...
... USA (July 8, 2010) To provide authors additional ... abstracts is now extended until July 31 for the ... held December 2-4 at the Washington Marriott Hotel in ... symposium on the following five topics: "Virus biology," "Pandemics, ...
Cached Medicine News:Health News:Self-Published Author Shares Her Personal Story of Hope Amidst Despair 2Health News:Iceland -- Working on its Popularity for Travellers, Iceland ProTravel Supports Ad Campaign "Inspired by Iceland" 2Health News:Iceland -- Working on its Popularity for Travellers, Iceland ProTravel Supports Ad Campaign "Inspired by Iceland" 3Health News:Extremely obese children have 40 percent higher risk of reflux disease of esophagus 2Health News:Extremely obese children have 40 percent higher risk of reflux disease of esophagus 3Health News:St. Elizabeth Dental Clinic Named one of the Best in the Nation 2Health News:North Shore-LIJ Becomes NY's First Health System to Require New Nurses to Get Bachelor's Degree 2Health News:North Shore-LIJ Becomes NY's First Health System to Require New Nurses to Get Bachelor's Degree 3Health News:Cell symposia meeting, Influenza: Translating basic insights, to be held Dec. 2-4, 2010 2
(Date:7/31/2015)... , July 31, 2015  Physicians and ... in the biopharmaceutical market. Patients are better informed ... selecting and switching therapies. This shift in power ... marketers, efforts toward patient-focused marketing. As ... marketers have learned it,s important to educate, communicate ...
(Date:7/31/2015)... HILL, N.C. , July 31, 2015  In ... of customers who are increasingly mobile, increasingly connected, and ... a growing variety of customer interaction channels and tools ... technology, including social media. According to ... the over the counter (OTC) segment in a call ...
(Date:7/31/2015)... YORK , July 31, 2015  Seeger Weiss LLP ... Administration (FDA) issued a warning letter to C.R. Bard, the ... not taking adequate strides to correct violations the agency found ... of these violations after the FDA cited them during Inspectional ... 2015, in Bard,s Tempe, AZ , location ...
Breaking Medicine Technology:Consumers Forcing Pharmaceutical Industry to Shift its Marketing Focus from Products to Patients 2Best Practices in Building World-Class Consumer & Over-the-Counter Call Centers 2Seeger Weiss LLP Reports That The FDA Has Issued A Warning Letter To IVC Filter Manufacturer, C.R. Bard 2Seeger Weiss LLP Reports That The FDA Has Issued A Warning Letter To IVC Filter Manufacturer, C.R. Bard 3
... AssureRx Health, Inc. today announced the appointments ... growth. Donald R. Wright, Jr. has been appointed ... John A. Bellano as senior vice president, sales & ... the development of AssureRx,s pharmacogenetic test, GeneSightRx®, and ...
... (NYSE: DGX ) today announced that it had ... of its common stock from its largest shareholder, an affiliate ... no longer hold any shares of common stock of Quest ... of a unique opportunity to enhance shareholder value and demonstrating ...
Cached Medicine Technology:AssureRx Appoints Senior Executives in Key Roles to Drive Company Growth 2AssureRx Appoints Senior Executives in Key Roles to Drive Company Growth 3Quest Diagnostics Agrees to Repurchase 15.4 Million Shares From Largest Shareholder 2
Inquire...
... II test is also available with Inverness ... greatly reduces the hands-on time required to ... testing. The Fecal-Quik-Prep device is a unique ... amount of hands-on time required to prepare ...
... Inverness Medical Professional Diagnostics now ... ELISA test for the screening and ... NMP22 Test Kit is a quantitative ... levels of NMP22 protein in the ...
... Our ELISA products for autoimmune testing ... ELISAs, as well as specific reflex tests ... Sm, Sm/RNP, SS-A (Ro), SS-B (La), Scl-70 ... family includes a full line of products ...
Medicine Products: