Navigation Links
New Drug Aids Muscle Function in Myasthenia Gravis
Date:8/18/2007

Trial of 16 patients saw 46% improvement in symptoms

FRIDAY, Aug. 17 (HealthDay News) -- A new drug -- oral EN101antisense -- reduced the severity of muscle weakness in patients with myasthenia gravis, researchers report.

Myasthenia gravis (MG), which affects about 20 in 100,000 people, causes fatigue and reduced strength in voluntary muscles. Other symptoms may include double vision, drooping eyelids, difficulty swallowing, or slurred speech.

The small open-label study included 16 MG patients who took daily doses of oral EN101antisense for four days and were monitored for a month. On average, the patients experienced a 46 percent reduction in symptom severity. Side effects included dryness of the eyes and mouth.

The study, published in the Aug. 14 issue of Neurology, was supported by the biotechnology company Ester Neuroscience Ltd.

"This is the first time we've been able to show that antisense is effective and safe when taken orally for a neurological disease," study author Dr. Zohar Argov, of the Hadassah Hebrew University Medical Center in Jerusalem, said in a prepared statement.

Further research is planned to study the effects of the drug over a longer period of time.

Antisense is a synthetic, short segment DNA that blocks production of specific proteins. Oral EN101antisense inhibits production of an enzyme called acetylcholine esterase, which plays an important role in the function of the neuromuscular junction, where nerves connect with muscles.

More information

The American Medical Association has more about myasthenia gravis.



-- Robert Preidt



SOURCE: American Academy of Neurology, news release, Aug. 13, 2007


'/>"/>

Copyright©2007 ScoutNews,LLC.

Page: 1

Related medicine news :

1. Mushroom and muscle loss
2. Blood Pressure Drugs maintain muscle strength
3. New treatment for muscle spasms
4. Protein can change worn muscle fibres
5. Stretching the muscles doesnt make them more resilient
6. Protein said to Improve Muscle Loss
7. ‘Protein’ Produced By Overstressed Heart Muscle a Strong Indicator Of Heart Diseae
8. Regeneration of muscle
9. Protein Found To Improve Muscle Loss
10. Strong Pelvic Muscles Found To Facilitate Childbirth
11. Molecule responsible for muscle repair identified
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/9/2016)... (PRWEB) , ... December 09, 2016 , ... Mediaplanet today ... for organ transplantation while encouraging readers to sign up as an organ donor for ... organ transplant. , An organ donor can save up to 8 saves through ...
(Date:12/9/2016)... PA (PRWEB) , ... December 09, 2016 , ... ... education program through the Pennsylvania Cable Network (PCN) during the summer of 2016. ... Injury Implementation Grant provided by the United States Department of Health and Human ...
(Date:12/8/2016)... ... December 08, 2016 , ... Russ DiGilio ... the first national #QuackGivesBack campaign which supported local breast cancer organizations during National ... Quack Gives Back initiative, and we’re very pleased with the participation ...
(Date:12/8/2016)... ... ... CURE Media Group, the nation’s leading digital and print media enterprise focused ... in efforts to combat lung cancer, announced CURE Media Group President Michael J. Hennessy, ... is honored to team up with Upstage Lung Cancer in order to make major ...
(Date:12/8/2016)... ... December 08, 2016 , ... ... for customers and employees that are both engaging and easy to use. Coming ... Technology, the software company revealed today its plans to roll out new AI-powered ...
Breaking Medicine News(10 mins):
(Date:12/8/2016)... Texas , Dec. 8, 2016 ... program that brings leading-edge laboratory services and management ... United States , allowing more doctors and ... health care management solutions. Logo - ... Hospital systems, under pressure to contain ...
(Date:12/8/2016)... 8, 2016 Information products and services provider ... in Scopus , the world,s largest abstract and citation database ... metrics for journals from over 5,000 publishers. The new set of ... subscribe to and when to adjust a journal,s editorial strategy. ... , , ...
(Date:12/8/2016)... A Small Business Innovative Research (SBIR) grant has been ... Phoenix -based NeuroEM Therapeutics, Inc. and ... seek to determine an optimal set of treatment parameters ... treat Alzheimer,s Disease. The grant will also investigate the ... neurologic disorders such as Parkinson,s Disease and PTSD. ...
Breaking Medicine Technology: