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New Data Presented at ACAAI Informs on the Safety and Efficacy of Nasacort AQ Nasal Spray in a Trial of Children Aged 2-5 Years Old with Year-Round Allergic Rhinitis
Date:11/10/2007

t AQ (-29.60 plus or minus 42.73 nmol/L; P=0.49), or placebo (-35.50 plus or minus 43.73; P=0.42). Similarly, after 6 months, patients treated with Nasacort AQ, showed no significant reduction from baseline in their average morning cortisol levels (-53.34 plus or minus 40.13 nmol/L; P=0.1900).

About Allergic Rhinitis

Allergic rhinitis is a swelling of the nasal passages, usually accompanied by sneezing, watery nasal discharge and itching of the nose and eyes. This medical condition is caused by an allergic reaction to allergens such as house dust, animal dander, or pollen. On any given day, 10,000 American children miss school because of allergic rhinitis, for a total of 2 million lost school days.

About Nasacort AQ

Nasacort AQ Nasal Spray is indicated for the treatment of the nasal symptoms of seasonal and perennial allergic rhinitis in adults and children 6 years of age and older.

The most commonly reported side effects with Nasacort AQ Nasal Spray were similar to vehicle placebo. In adults and children ages 12 and older, they were: pharyngitis 5.1% vs 3.6%, epistaxis 2.7% vs 0.8%, and increase in cough 2.1% vs 1.5%. In studies including children ages 6 to 11, they were: pharyngitis 7.4% vs 6.4%, increase in cough 7.0% vs 6.4%.

About sanofi-aventis

Sanofi-aventis, a leading global pharmaceutical company, discovers, develops and distributes therapeutic solutions to improve the lives of everyone. Sanofi-aventis is listed in Paris (EURONEXT: SAN) and in New York (NYSE: SNY).

Forward-looking statements

This press release contains forward-looking statements as defined in the Private Securities Litigation Reform Act of 1995, as amended. Forward-looking statements are statement
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