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New Data Demonstrate RISPERDAL(R) CONSTA(R) (Risperidone) Long-Acting Treatment May Improve Health Outcomes and Reduce Hospitalizations in Patients with Schizophrenia
Date:5/19/2009

ted that patients with schizophrenia in the Veterans Affairs (VA) system who also suffered from other medical or psychiatric illnesses had fewer and shorter-duration psychiatric hospitalizations after the initiation of RISPERDAL(R) CONSTA(R).

This analysis identified all VA patients with schizophrenia who began RISPERDAL(R) CONSTA(R) between October 1, 2005 and September 30, 2006 and received at least four (total) injections (N=924). The analysis compared changes in health services use between 12 months prior to and 12 months after initiation of RISPERDAL(R) CONSTA(R). Results showed that between the pre- and post- RISPERDAL(R) CONSTA(R) initiation periods, the mean number of psychiatric hospitalizations and length of stay significantly decreased for patients with three or more concurrent illnesses, while psychiatric-related outpatient visits increased.(4)

"The results of this analysis suggest that long-acting therapy may reduce the need for repeated hospitalizations and improve everyday psychiatric follow-up among patients with complex medical histories," continued Dirani.

A limitation of these two studies is that they did not compare RISPERDAL(R) CONSTA(R) to placebo or other treatments.

The studies were presented and sponsored by Ortho-McNeil Janssen ScientificAffairs.

About Schizophrenia

According to the National Institute of Mental Health, an estimated one percent of the U.S. population suffers from schizophrenia - a brain disorder that impairs a person's ability to think clearly, relate to others and distinguish between reality and imagination. It typically develops in adolescence or the early 20s, although symptoms may not become immediately obvious.

About RISPERDAL(R) CONSTA(R)

RISPERDAL(R) CONSTA(R) (risperidone) Long-Acting Treatment (RLAT) is a long-acting injectable atypical antipsychotic therapy used for the treatment of
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SOURCE Janssen
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