Navigation Links
New Criteria Could Expand Number of Liver Transplant Candidates
Date:12/5/2008

Closer look at tumors boosts chances for those denied under current protocols, study says

FRIDAY, Dec. 5 (HealthDay News) -- Many patients with liver cancer who don't meet criteria used to select transplant patients could actually be good candidates for liver transplantation, according to an Italian study.

The Milan criteria specifies that liver cancer patients with a single tumor of 5 centimeters or less in diameter, or three or fewer tumors, each no more than 3 cm in diameter and with no macrovascular invasion, can expect an excellent outcome after liver transplantation, with only a 10 percent risk of cancer recurrence.

Survival of patients who don't meet the criteria is unpredictable, and there are no evidence-based guidelines to help doctors select patients who exceed the criteria but might benefit from receiving a new liver, according to background information in the study.

Researchers at Italy's National Cancer Institute analyzed data from a Web survey of liver cancer specialists who provided information about 1,112 liver cancer patients who didn't meet the Milan criteria but had a liver transplant. In this group of patients, those without microvascular invasion had an overall five-year survival rate of 71 percent, similar to that of patients that meet the Milan criteria.

After studying this data, Dr. Vincenzo Mazzaferro and colleagues developed a new prognostic model that could be used to expand the Milan criteria and help identify patients whose odds of survival could be improved by having a liver transplant. In this "Up-to-seven" criteria, the seven refers to the maximum score based on adding the size (in centimeters) of the largest tumor to the total number of tumors.

"A more precise estimation of survival contouring individual tumor characteristics by use of the Up-to-seven criteria could replace the current dual [yes/no] approach to transplant candidacy based on the strict Milan criteria for patients with [liver cancer]," the researchers wrote.

The study was published online and in the January print issue of The Lancet Oncology.

More information

The American Liver Foundation has more about liver cancer.



-- Robert Preidt



SOURCE: The Lancet Oncology, news release, Dec. 4, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. How Patients Can Meet the Criteria for Insulin Pump Therapy
2. New Rhode Island Hospital study shows inadequate diagnostic criteria for eating disorders
3. Capital BlueCross CEO Says Meaningful Statewide Competition Must Be Key Criteria in Pennsylvanias Review of Proposed Highmark-IBC Merger
4. Landmark Articles Published by QualityMetric Scientists Report Improvements in Short Form Health Status Measures and Establish Criteria for Future Development
5. BMI criteria for obesity surgery should be lowered, UT Southwestern researchers suggest
6. Criteria Predict Womens 5-Year Risk for Fracture
7. New Test Criteria Spots Rheumatoid Arthritis Sooner
8. Health Care Leaders to Use New National Criteria for Patient-Centered Medical Home
9. Nations healthcare leaders to announce new NCQA criteria for PCMH Model at healthcare summit
10. Researchers estimate about 9 percent of US children age 8 to 15 meet criteria for having ADHD
11. Robotic Device Could Help Stroke Patients
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Criteria Could Expand Number of Liver Transplant Candidates
(Date:5/30/2016)... GA (PRWEB) , ... May 30, 2016 , ... ... on June 6th, while Shaolin warrior 8-day-8 and 8-night special intensive summer training ... Shaolin Institute annual overnight summer camp offers families and children a fun and ...
(Date:5/29/2016)... , ... May 29, 2016 , ... Whole Health Supply ... their new KlipPro KP-240L clipper is available to the public. This is an unusual ... substantially wider than the average clipper. , Everything about this product is concentrated on ...
(Date:5/28/2016)... ... May 28, 2016 , ... "Color Grading media can be time consuming ... onto their media," said Christina Austin - CEO of Pixel Film Studios. , ... easily add stylish color grades to their footage. A LUT is a Lookup Table ...
(Date:5/28/2016)... ... 2016 , ... In a part of the city where’s it’s easy to spot the neon ... is hoping to attract diners with a taste for real food. , On ... doors to Cornerstone Grill, an urban casual restaurant focusing on dishes made by hand with ...
(Date:5/27/2016)... ... ... Two director-level employees of Horizon Blue Cross Blue Shield of New Jersey ... The award recognizes businesswomen who excel in their fields and who have made ... (Managed Long-Term Services and Supports) Program at Horizon NJ Health and Theresa Ponton, Director ...
Breaking Medicine News(10 mins):
(Date:5/25/2016)... PARIS , May 25,2016 ... with the near-infrared Cellvizio platform for urological and ... MKEA, OTCQX: MKEAY) inventor of Cellvizio®, the multidisciplinary ... important regulatory milestone in the US with the ... Food and Drug Administration (FDA). This new FDA ...
(Date:5/25/2016)... and GERMANTOWN, Maryland , May 25, 2016 ... ; Frankfurt Prime Standard: QIA) today announced that the company ... Diagnostics GmbH to develop and commercialize predictive assays in oncology. ... as a marker to predict effectiveness of anthracycline treatment in ... "We are pleased to partner with Therawis, which developed the ...
(Date:5/25/2016)... NEW YORK , May 25, 2016 ... Device Market Size, Share, Development, Growth and Demand Forecast ... Insulin Syringe, Insulin Pump and Others)" published by P&S ... valued at $9,998.3 million in 2015, and it is ... 2016-2022. Based on type, the insulin pump segment is ...
Breaking Medicine Technology: