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New Comprehensive Chromosome Screening Program at Pacific Fertility Center Refines Embryo Selection, Improves Pregnancy Rates
Date:3/6/2013

San Francisco, CA (PRWEB) March 06, 2013

Comprehensive Chromosome Screening (CCS) helps reduce multiple pregnancies and the risks that accompany them. It allows selection of high-quality embryos for transfer, which not only improves implantation rates for women, but also reduces miscarriage rates.

CCS uses advanced microarray technology to test chromosomes with more than 99 percent accuracy. It allows selection of high-quality embryos for transfer, which not only improves implantation rates, but also reduces miscarriage rates. And, because CCS reliably identifies high-quality embryos, patients don't have to "hedge their bets" by having several embryos transferred at one time.

In the past, it was difficult to know which embryos were of high quality. An embryo could look fine under the microscope, but have an abnormal number of chromosomes. In fact, when researchers examine the DNA within embryos, they find that 40–90 percent of normal-appearing embryos are genetically abnormal.

Earlier types of pre-implantation genetic testing had significant shortcomings. These tests involved removal (biopsy) of cells at an early embryo stage. Sampling of single cells at an early stage was not necessarily representative of the whole embryo, and thus certain abnormalities could be missed. Early biopsy also appeared to be detrimental to the health of some embryos.

With highly sensitive CCS techniques, it is now possible to test all 23 pairs of chromosomes in an embryo at a later stage, reliably and safely learning the exact number of chromosomes. This makes it possible to identify embryos with normal genetic structure and thus select the highest-quality embryos out of a group for transfer.

How does it work at cutting-edge facilities such as the Pacific Fert
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