Navigation Links
New Compound May Fight HIV
Date:4/30/2009

Study in mice finds added benefit from cholesterol-reducing agent ,,

THURSDAY, April 30 (HealthDay News) -- Drugs that stimulate cells to release cholesterol might prove effective in fighting the HIV virus, which causes AIDS, a new study suggests.

George Washington University researchers tested a compound called TO-901317 in mice and found that the treatment restored cholesterol outflow from HIV-infected scavenger cells (macrophages) and white blood cells (lymphocytes). Release of cholesterol from these cells had been greatly inhibited by HIV.

The study also found that the compound "potently suppressed HIV-1 in both cell types," and this anti-HIV effect led to significant reductions of HIV levels in the mice.

The findings were to be presented Thursday at the American Heart Association's conference in Washington, D.C., on arteriosclerosis, thrombosis and vascular biology.

People with HIV face an increased risk of atherosclerosis, which leads to coronary artery disease and heart attack, according to background information in a news release from the Heart Association. The researchers said that the findings suggest a new approach to reducing infectivity and lowering cholesterol levels in people with HIV.

Drugs such as TO-901317 "may provide a double benefit to HIV-infected patients by reducing HIV replication and preventing the development of atherosclerosis with HIV infection," they said.

More information

The U.S. National Institute of Allergy and Infectious Diseases has more about HIV treatment.



-- Robert Preidt



SOURCE: American Heart Association, news release, April 30, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Coloring Compound in Fruits, Veggies May Cut Colon Cancer Risk
2. Sugary Sodas High in Diabetes-Linked Compound
3. Red wine compound shown to prevent prostate cancer
4. CutisPharma Selected by Medicine Shoppe International as Preferred Vendor for Unit-of-Use Compounding Kits
5. A Chinese medicine compound has satisfactory anti-cancer effects on hepatocellular carcinoma
6. VioQuest to Present Data on Oncology Compounds VQD-002 and Lenocta(TM) at AACR-NCI-EORTC International Meeting
7. Organon Signs an Exclusive, Worldwide Licence Agreement on Advanced Antithrombotic Compounds With Endotis Pharma
8. Primus Innovations and Health Robotics Launch Strategic Partnership to Accelerate Transformation in Chemotherapy Compounding
9. Cannabis Compound May Stop Metastatic Breast Cancer
10. Prostate Cancer Treatments Often Compound Existing Health Problems
11. Pharmacopeia and GlaxoSmithKline Collaboration Identifies Two Additional Lead Compounds
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Compound May Fight HIV
(Date:5/26/2016)... ... 2016 , ... According to the Webster’s dictionary, a hippie is defined as ... one company is going against the norm with a line of all-natural skincare that’s ... the green space is proud to announce its latest retail partnership with the Vitamin ...
(Date:5/26/2016)... ... May 26, 2016 , ... ... weekend to host their second pop-up shop for three consecutive weekends. The pop-up ... to the Santa Barbara community, a community full of women who appreciate the ...
(Date:5/26/2016)... , ... May 26, 2016 , ... ... been hired as FluidEdge’s Vice President of Business Intelligence and Informatics, effective immediately. ... has demonstrated success leading teams as a healthcare business and financial strategist for ...
(Date:5/25/2016)... ... ... The United States Food and Drug Administration (FDA) has now cleared Capillus® laser ... the company is the first and only manufacturer of low level laser therapy (LLLT) ... , “This new level of clearance substantiates what many physicians have experienced firsthand ...
(Date:5/25/2016)... Pembroke Pines, FL (PRWEB) , ... ... ... Hospital West has received the American Heart Association/American Stroke Association's Get With ... Plus designation. , This achievement, a second for Memorial Healthcare System, ...
Breaking Medicine News(10 mins):
(Date:5/24/2016)... -- Dutch surgeons have launched a ground-breaking medical app ... treat patients on a global scale. Medical professionals from ... and the US have already signed up for the ... a totally secure environment. Education  "Imagine a ... with a surgeon at Harvard to treat a bomb victim via ...
(Date:5/23/2016)... May 23, 2016 According ... Equipment Market by Product (Wheelchair, Scooters, Medical Beds, ... Care, Critical Care, Wound), Accessories (Lifting, Transfer) & ... 2021", published by MarketsandMarkets, the patient handling equipment ... by 2021 at a CAGR of 10.5% during ...
(Date:5/23/2016)... 2016 Diplomat Pharmacy, Inc. (NYSE: DPLO) announced today ... programs. The hands-on learning experience is a 12-week summer ... Fellowship and Internship programs bring ... and interns are provided optional housing free of charge ... at the Riverfront Residence Hall to foster communication and ...
Breaking Medicine Technology: