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New Collagen Meniscus Implant Opens New Vista for Knee Repair
Date:8/4/2009

ation work in 1989 and then the American Orthopedics Society for Sports Medicine's Cabaud Award in 1990, never imagined the process would take 22 years from invention to FDA-approval in the U.S.

The implant, now marketed by ReGen Biologics, Inc., the company Stone co-founded with colleague Richard Steadman M.D., in 1989, underwent a tortuous course. The initial clinical trial in 10 patients was completed at The Stone Clinic in San Francisco in the early 1990s with successful results. Trials were repeated again with successful results, leading to a wide clinical trial in the U.S. and approval in Europe where more than 3,000 implants have already been performed. The U.S. trial and gaining FDA approval took until the end of 2008. Now, over 20 years later, Stone has the joy of implanting his device in his own patients.

"We have become very skilled at complete replacement of the meniscus cartilage with allograft menisci, even in patients with arthritis," Stone said. "However, many patients with healthy knees - but who are still missing a portion of their meniscus - will benefit from a segmental re-growth. The device is perfectly engineered for this type of procedure. It is also a great augmentation device for difficult-to-repair meniscus tears, such as bucket-handle tears and horizontal cleavage tears with missing volume. Stone added, "This week, we also used the collagen meniscus implant as a growth factor carrier for platelet-rich plasma to augment the body's ability to regenerate tissue in a chronic bucket-handle tear in a young athlete. I expect it will also be a great stem cell carrier."

Stone's medical odyssey demonstrates how long the process of invention can be, but the outcome is worth it for those willing to persevere.

For more information see: www.stoneclinic.com.

    The Stone Clinic
    3727 Buchanan
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SOURCE The Stone Clinic
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