Navigation Links
New Clues to Treating Immune System Disorders
Date:5/19/2010

Two noninvasive probes send snapshots of immune system in action, researchers say

WEDNESDAY, May 19 (HealthDay News) -- Researchers are reporting that they've used two different types of noninvasive probes to uncover the roles played by different types of cells in the immune system.

One of the probes, known as an FDG, is commonly used in PET scans to track how cells break down glucose (sugar), while the so-called FAC probe -- developed recently at the University of California, Los Angeles -- measures the activity of specific biochemical pathways.

The probes may help doctors evaluate treatments that target different cells in the immune system, senior study author Dr. Owen Witte, a professor of microbiology, immunology and molecular genetics at the University of California at Los Angeles, said in a news release from the school.

"We demonstrated with this study that each probe targets different cells in the immune system with a high degree of specificity," said Witte, who added that the probes have special powers of detection, with the FDG probe recognizing immune system players like activated macrophages (immune scavenger cells) and the FAC probe recognizing activated lymphocytes (cells that lead the immune system charge on infected or cancerous cells).

"When tested sequentially, the combined information from the scans using the two probes gives you a better status of immune response," Witte said.

The probes were tested on mice and will be later tested on humans. Researchers think they could provide insight into how the immune system responds to diseases such as rheumatoid arthritis, inflammatory bowel disease and multiple sclerosis.

"This could give us another way to measure the efficacy of certain drugs," Witte said. "With some drugs, you could measure a change in the immune response within a week."

The study appears May 17 in the online edition of the Journal of Clinical Investigation.

More information

For more about the immune system, visit the U.S. National Institute of Allergy and Infectious Diseases.



-- Randy Dotinga



SOURCE: University of California at Los Angeles, May 17, 2010, news release.


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. New Clues to Treating an Aggressive Breast Cancer
2. Pigs Yield Clues to Cystic Fibrosis-Related Lung Disease
3. New Clues Shed Light on Sperm Function, Male Fertility
4. Ovarian cancer study offers vital clues for new therapies
5. Change in breast density over time provides clues about breast cancer risk
6. Lab that probes genetic clues to disease is poised for major expansion
7. More Clues Emerge on How HIV Infects Women
8. Scientists Find Clues to How the Body Fights Off HIV
9. New Clues to Pregnancy-Associated Breast Cancer
10. Clues Found to How Different Flu Vaccines Work
11. Clues to pregnancy-associated breast cancer found
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... June 27, 2016 , ... Quality metrics are proliferating ... many ways they remain in the eye of the beholder, according to experts who ... of The American Journal of Managed Care. For the full issue, click here ...
(Date:6/26/2016)... ... June 26, 2016 , ... PawPaws brand pet supplements ... was developed to enhance the health of felines. The formula is all-natural and is ... herbs in the PawPaws Cat Kidney Support Supplement Soft Chews are Astragalus ...
(Date:6/25/2016)... D.C. (PRWEB) , ... June 25, 2016 , ... ... discuss health policy issues and applications at AcademyHealth’s Annual Research Meeting June 26-28, ... their work on several important health care topics including advance care planning, healthcare ...
(Date:6/25/2016)... ... 2016 , ... "With 30 hand-drawn hand gesture animations, FCPX users can easily ... of Pixel Film Studios. , ProHand Cartoon’s package transforms over 1,300 hand-drawn pictures ... . Simply select a ProHand generator and drag it above media or text in ...
(Date:6/25/2016)... Oklahoma City, Oklahoma (PRWEB) , ... June 25, ... ... to helping both athletes and non-athletes recover from injury. Recently, he has implemented ... for the Oklahoma City area —Johnson is one of the first doctors to ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016   Bay ... Rehabilitation Network,s Dean Center for Tick Borne ... Medicine and Rehabilitation, MIT Hacking Medicine, University of ... Innovation, today announced the five finalists of ... Lyme disease.  More than 100 scientists, clinicians, researchers, ...
(Date:6/24/2016)... , June 24, 2016 ... the "Structural Electronics 2015-2025: Applications, Technologies, Forecasts" ... In-Mold Electronics, Smart Skin, Structural ... Structural electronics involves electronic and/or ... protective structures, replacing dumb structures such as vehicle ...
(Date:6/24/2016)... , June 24, 2016 Dehaier Medical Systems ... "Company"), which develops, markets and sells medical devices and ... , signed a strategic cooperation agreement with Hongyuan Supply ... Supply Chain") on June 20, 2016, to develop Dehaier,s ... strategic cooperation agreement, Dehaier will leverage Hongyuan Supply Chain,s ...
Breaking Medicine Technology: