Navigation Links
New Clues to Treating Immune System Disorders
Date:5/19/2010

Two noninvasive probes send snapshots of immune system in action, researchers say

WEDNESDAY, May 19 (HealthDay News) -- Researchers are reporting that they've used two different types of noninvasive probes to uncover the roles played by different types of cells in the immune system.

One of the probes, known as an FDG, is commonly used in PET scans to track how cells break down glucose (sugar), while the so-called FAC probe -- developed recently at the University of California, Los Angeles -- measures the activity of specific biochemical pathways.

The probes may help doctors evaluate treatments that target different cells in the immune system, senior study author Dr. Owen Witte, a professor of microbiology, immunology and molecular genetics at the University of California at Los Angeles, said in a news release from the school.

"We demonstrated with this study that each probe targets different cells in the immune system with a high degree of specificity," said Witte, who added that the probes have special powers of detection, with the FDG probe recognizing immune system players like activated macrophages (immune scavenger cells) and the FAC probe recognizing activated lymphocytes (cells that lead the immune system charge on infected or cancerous cells).

"When tested sequentially, the combined information from the scans using the two probes gives you a better status of immune response," Witte said.

The probes were tested on mice and will be later tested on humans. Researchers think they could provide insight into how the immune system responds to diseases such as rheumatoid arthritis, inflammatory bowel disease and multiple sclerosis.

"This could give us another way to measure the efficacy of certain drugs," Witte said. "With some drugs, you could measure a change in the immune response within a week."

The study appears May 17 in the online edition of the Journal of Clinical Investigation.

More information

For more about the immune system, visit the U.S. National Institute of Allergy and Infectious Diseases.



-- Randy Dotinga



SOURCE: University of California at Los Angeles, May 17, 2010, news release.


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. New Clues to Treating an Aggressive Breast Cancer
2. Pigs Yield Clues to Cystic Fibrosis-Related Lung Disease
3. New Clues Shed Light on Sperm Function, Male Fertility
4. Ovarian cancer study offers vital clues for new therapies
5. Change in breast density over time provides clues about breast cancer risk
6. Lab that probes genetic clues to disease is poised for major expansion
7. More Clues Emerge on How HIV Infects Women
8. Scientists Find Clues to How the Body Fights Off HIV
9. New Clues to Pregnancy-Associated Breast Cancer
10. Clues Found to How Different Flu Vaccines Work
11. Clues to pregnancy-associated breast cancer found
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/28/2017)... ... March 28, 2017 , ... Neurotechnology , a provider ... and attendance tracking products: the new NCheck Cloud Bio Attendance cloud-based service and ... biometric face recognition to enable users to check in and out from anywhere ...
(Date:3/28/2017)... ... March 28, 2017 , ... In its ongoing ... website has recently developed and published an informational resource that addresses frequently asked ... on common inquiries the site’s team of third party administrator (TPA) contributors regularly ...
(Date:3/28/2017)... ... March 28, 2017 , ... A minimally invasive ... “perfect smile.” The National Association of Dental Laboratories (NADL) is informing dentists about ... aware of when utilizing dental laboratories and technicians that create these veneers. ...
(Date:3/28/2017)... Square, PA (PRWEB) , ... March 28, 2017 , ... ... online and across a variety of business channels. , While many results are ... of any public relations program. , When it comes to measurement, firms should ...
(Date:3/28/2017)... ... 28, 2017 , ... Silicon Valley Hair Institute, the San Francisco Bay Area ... about women’s hair loss. Although hair transplant procedures can be seen as more of ... genetics can be two reasons a woman may see her hair thinning. , “We ...
Breaking Medicine News(10 mins):
(Date:3/28/2017)... TAIPEI, Taiwan , March 28, 2017 /PRNewswire/ ... medical device company, is pleased to announce ... Series A investment of Panther Orthopedics, Inc., a ... pioneering innovative dynamic fixation solutions for orthopedic extremity ... market continues to expand rapidly, primarily due to ...
(Date:3/27/2017)... 27, 2017 The National University of ... data analytics company, signed a Memorandum of Understanding ... delivery in the region. Under ... Research and Technology (BIGHEART) at NUS and Holmusk ... related to healthcare IT and medical device development. ...
(Date:3/27/2017)... -- Summary This report provides all ... its partnering interests and activities since 2010. Description The ... insight into the partnering activity of one of the world,s ... are prepared upon purchase to ensure inclusion of the most ... report will be delivered in PDF format within 1 working ...
Breaking Medicine Technology: