Navigation Links
New Clues to Treating Immune System Disorders
Date:5/19/2010

Two noninvasive probes send snapshots of immune system in action, researchers say

WEDNESDAY, May 19 (HealthDay News) -- Researchers are reporting that they've used two different types of noninvasive probes to uncover the roles played by different types of cells in the immune system.

One of the probes, known as an FDG, is commonly used in PET scans to track how cells break down glucose (sugar), while the so-called FAC probe -- developed recently at the University of California, Los Angeles -- measures the activity of specific biochemical pathways.

The probes may help doctors evaluate treatments that target different cells in the immune system, senior study author Dr. Owen Witte, a professor of microbiology, immunology and molecular genetics at the University of California at Los Angeles, said in a news release from the school.

"We demonstrated with this study that each probe targets different cells in the immune system with a high degree of specificity," said Witte, who added that the probes have special powers of detection, with the FDG probe recognizing immune system players like activated macrophages (immune scavenger cells) and the FAC probe recognizing activated lymphocytes (cells that lead the immune system charge on infected or cancerous cells).

"When tested sequentially, the combined information from the scans using the two probes gives you a better status of immune response," Witte said.

The probes were tested on mice and will be later tested on humans. Researchers think they could provide insight into how the immune system responds to diseases such as rheumatoid arthritis, inflammatory bowel disease and multiple sclerosis.

"This could give us another way to measure the efficacy of certain drugs," Witte said. "With some drugs, you could measure a change in the immune response within a week."

The study appears May 17 in the online edition of the Journal of Clinical Investigation.

More information

For more about the immune system, visit the U.S. National Institute of Allergy and Infectious Diseases.



-- Randy Dotinga



SOURCE: University of California at Los Angeles, May 17, 2010, news release.


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. New Clues to Treating an Aggressive Breast Cancer
2. Pigs Yield Clues to Cystic Fibrosis-Related Lung Disease
3. New Clues Shed Light on Sperm Function, Male Fertility
4. Ovarian cancer study offers vital clues for new therapies
5. Change in breast density over time provides clues about breast cancer risk
6. Lab that probes genetic clues to disease is poised for major expansion
7. More Clues Emerge on How HIV Infects Women
8. Scientists Find Clues to How the Body Fights Off HIV
9. New Clues to Pregnancy-Associated Breast Cancer
10. Clues Found to How Different Flu Vaccines Work
11. Clues to pregnancy-associated breast cancer found
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/21/2017)... , ... January 21, 2017 , ... ... its new medical office in Petaluma, located at 167 Lynch Creek Way. The ... to SRO sports medicine and rehabilitation services and on-site x-ray services. ...
(Date:1/20/2017)... ... , ... A new partnership between Goodwill® and Roadie, Inc. aims to make ... clothes to couches to dressers and bicycles. Roadie — the national on-the-way delivery network ... donation center through February 28th. , “January is an exciting time when resolutions ...
(Date:1/20/2017)... ... , ... Bionic Sports Nutrition LLC, an American company devoted to developing high-quality ... January ECRM Trade Show in Hilton Head, SC. , Bionic Sports Nutrition manufactures ... its products to all clients at reasonable prices. At the ECRM trade show, it ...
(Date:1/20/2017)... ... ... Michael and Betsy Brauser celebrated 5 years of Betsy’s participation in a ... has been life-saving as she has been on the trial for more than six ... ovarian cancer in 2009. She underwent standard chemotherapy but a year later went to ...
(Date:1/20/2017)... ... , ... “The Angel”: a heartwarming and earnest tale of faith and ... children. “The Angel” is the creation of published author, Marjorie Lund-Fontaine, a former professional ... writer. , When asked of her new book, Marjorie says, “‘The Angel’ was written ...
Breaking Medicine News(10 mins):
(Date:1/19/2017)... RATON, Fla. , Jan. 19, 2017 /PRNewswire/ ... a medical device company specializing in the treatment ... such as keloids, with superficial radiation therapy, today ... and full year 2016 financial results on Thursday, February ... The Company will hold a conference call with ...
(Date:1/19/2017)... LEXINGTON, Massachusetts , January 19, 2017 ... SHPG ) announced that the U.S. Food and Drug ... resubmission of a New Drug Application (NDA) for SHP465, ... being evaluated as a potential once-daily treatment for Attention-Deficit/Hyperactivity ... decision on or around June 20, 2017, the designated ...
(Date:1/19/2017)... -- Pfizer joins Astex, AstraZeneca, GlaxoSmithKline, ...   Major research investment to work ...   The Milner Therapeutics Institute today announces ... partner to the Milner Therapeutics Consortium. Pfizer has agreed ... of materials between industry and academia and allocation of ...
Breaking Medicine Technology: