Navigation Links
New Clues to Stopping Colitis-Linked Cancer
Date:2/2/2009

2 immune system proteins could hold the key, study finds

MONDAY, Feb 2 (HealthDay News) -- Two immune system proteins may someday help doctors treat and prevent colitis-associated cancer (CAC), a new study suggests.

The Interleukin 6 (IL-6) cytokine, a protein released by cells in the immune system, plays a key role in tumor production of colitis-associated cancer, according to a study on mice done at the University of California, San Diego, School of Medicine. This work by IL-6 appears dependent on STAT3, a transcription factor that encourages cancer development, according to the findings published in the Feb. 3 online edition of Cancer Cell.

The findings suggest that targeting IL-6 and Stat3 mught be a way to stop or treat CAC, said lead researcher Michael Karin, a professor of pharmacology and pathology at the university and a member of its cancer center. For example, when researchers removed STAT3 from intestinal epithelial cells, the development of colitis-associated cancer stopped in the mice.

Inflammatory bowel disease, such as ulcerative colitis, puts people at a greater risk of developing colorectal cancer. Nearly half of people with the malignancy die from it.

The new study backs previous work by the San Diego researchers, who suspected that IL-6 helped foster chronic inflammation and the survival of malignant cells that helped promote cancer.

More information

The U.S. National Cancer Institute has more about colorectal cancer.



-- Kevin McKeever



SOURCE: University of California - San Diego, news release, Feb. 2, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Investigators uncover intriguing clues to why persistent acid reflux sometimes turns into cancer
2. Online Epidemic Gives Clues to Bird Flu Spread
3. New knock-out gene model provides molecular clues to breast cancer
4. New clues to breast cancer development in high-risk women
5. Clues to Cell Death Could Fight Disease
6. Genes Give Clues to Newborn Lung Disease
7. Mouse Study Gives Clues to Colitis
8. VivoMetrics LifeShirt Going to South Pole to Uncover Clues to High-Altitude Illness
9. Protein Gives Clues to Pancreatic Cancer
10. A longer-living, healthier mouse that could hold clues to human aging
11. Clues to ensuring anti-HIV drugs are taken in Africa
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Clues to Stopping Colitis-Linked Cancer
(Date:9/21/2014)... PA (PRWEB) September 21, 2014 "I ... their legs and back but haven’t the money for ... I’d like to have such a product for myself." ... effective way to stretch the thigh muscles and align ... as well as relieves discomfort of pinched nerves. Compact ...
(Date:9/21/2014)... Best Cheap Hosting USA, one of ... Bluehost and GreenGeeks are the best Reseller hosting suppliers ... reseller hosting supplier. Actually, these companies have outperformed their ... support. People can get the best web hosting at ... According to the manager, reseller hosting is a very ...
(Date:9/21/2014)... (PRWEB) September 21, 2014 To accommodate ... e-powered platform and provide more trendy items. Recently, the ... . By offering the new and elegant wedding gowns, ... get what they need in an easy way. Its ... deeply discounted rates, from 12% off to 62% off. ...
(Date:9/21/2014)... 21, 2014 “Cluster headaches are sometimes ... and difficult to resolve,” said Steve Young of Ew ... of a pain that is more intense.” , “It ... cluster headaches, or migraines, that medical research is pointing ... system,” he added. , Serotonin (5-HT, 5-hydroxytryptamine) is a ...
(Date:9/21/2014)... C8 lawsuits move forward in the ... list of 20 possible C8 lawsuits selected for ... reports Wright & Schulte LLC. Court records show these ... C8 lawsuits filed that represent individuals who purportedly developed ... result of being exposed to water contaminated by the ...
Breaking Medicine News(10 mins):Health News:Best Cheap Hosting USA Announces The Best Reseller Hosting Suppliers In 2014 2Health News:Angeldress.co.uk Launches New Range Of 2014 Vintage Wedding Dresses In Its Online Store 2Health News:Homeostasis: Equinox Serotonin (5HT) Headache Stories ~ New on the Bryan William Brickner Blog 2Health News:C8 Lawsuit Claims Move Forward as Six Possible Cases for Bellwether Trials Selected in DuPont Water Contamination Lawsuits, Reports Wright & Schulte LLC 2Health News:C8 Lawsuit Claims Move Forward as Six Possible Cases for Bellwether Trials Selected in DuPont Water Contamination Lawsuits, Reports Wright & Schulte LLC 3Health News:C8 Lawsuit Claims Move Forward as Six Possible Cases for Bellwether Trials Selected in DuPont Water Contamination Lawsuits, Reports Wright & Schulte LLC 4
... Washington Teenage girls are setting new trends in drug ... , a report has shown. ,Teen boys have ... Wanting a slice of the vice, teen girls have become ... drugs, according to the White House Office of National Drug ...
... finds that sleep deprivation can adversely affect a persons ... of gains and making light of ones losses ... neural underpinnings of risky decision making under conditions of ... studied healthy volunteers as they underwent functional magnetic resonance ...
... not get training posts through the flawed Medical Training ... government is stalling on a new contract for ... figures show that 34,250 doctors are chasing 18,500 specialist ... far given no commitment that trainee doctors will be ...
... definite link between pregnancy, migraine and stroke, US researchers ... one. ,In fact, Cheryl Bushnell, assistant professor ... Disease in Durham, explained that pregnant women who suffered ... than pregnant women who did not suffer migraine. ...
... Science & Technology, Government of India and the ... today to address a major obstacle in AIDS ... elicit neutralizing antibodies against HIV. A new Indian ... and the Department of Biotechnology, will comprise top ...
... disturbing link between Reclast, made by Novartis AG and Fosamax manufactured ... in a small number of women users. Both are known bone-building ... more pronounced with Reclast, given as an annual shot. But there ... took the leading osteoporosis pill, Fosamax by Merck & Co. They ...
Cached Medicine News:Health News:Sleep Deprivation can Affect Competent Decision-making 2Health News:Junior Doctors Facing More Misery Because of Contract Deadlock: BMA 2Health News:DBT And IAVI Forge Partnership To Develop Next Generation Vaccine Candidates 2Health News:DBT And IAVI Forge Partnership To Develop Next Generation Vaccine Candidates 3Health News:Anti-osteoporosis Drugs Could Result in Irregular Heart Rhythm, New Study 2
(Date:9/19/2014)... Sept. 19, 2014 /PRNewswire-iReach/ -- "United ... 2020″, provides key market data on ... market. The report provides value, in ... (in units) within market categories – ... Esophagoscopes & Gastroscopes, Duodenoscopes, Laparoscopes, Hysteroscopes, ...
(Date:9/19/2014)... 19, 2014  The board of directors of AbbVie ... cash dividend of $0.42 per share.  ... stockholders of record at the close of business on ... a global, research-based biopharmaceutical company formed in 2013 following ... its expertise, dedicated people and unique approach to innovation ...
(Date:9/19/2014)... 19, 2014  4WEB Medical announces the formal launch ... ankle osteotomy implants on the market today at ... meeting in Chicago .  The Osteotomy ... osteotomy needs with 74 size options included in one ... of only 15 to 18 implant sizes, which limited ...
Breaking Medicine Technology:United States General Surgery Devices Market to 2020 - Endoscopy, Bariatric Surgery, Aesthetic Lasers and Energy, Biopsy Devices, Hernia Repair, Non-Vascular Stents 2United States General Surgery Devices Market to 2020 - Endoscopy, Bariatric Surgery, Aesthetic Lasers and Energy, Biopsy Devices, Hernia Repair, Non-Vascular Stents 3United States General Surgery Devices Market to 2020 - Endoscopy, Bariatric Surgery, Aesthetic Lasers and Energy, Biopsy Devices, Hernia Repair, Non-Vascular Stents 4United States General Surgery Devices Market to 2020 - Endoscopy, Bariatric Surgery, Aesthetic Lasers and Energy, Biopsy Devices, Hernia Repair, Non-Vascular Stents 54WEB Medical Unveils 3D-Printed Osteotomy Truss System 2
... CarePoint Partners (CarePoint) today announced that it has ... pharmacy services in Austin, Texas and infusion pharmacy ... area. The Austin location complements CarePoint,s Dallas and ... its southeastern footprint with this expansion into the ...
... Hospira, Inc. (NYSE: HSP ), a leading ... the company will present at the Bank of America / ... 2011, in Las Vegas. The presentation is scheduled ... 11, 2011.  It will be available to all interested parties ...
Cached Medicine Technology:CarePoint Partners Expands Texas Presence and Opens Georgia Market With Acquisition of Premier Infusion 2
Alexander periosteal elevators....
Lambotte periosteal elevators....
Cottle periosteal & skin elevator, 7 1/2", slightly curved blade, 9 mm wide....
Dolwick-Reich Condyle periosteal elevator, 17.5 cm, 7"....
Medicine Products: