Navigation Links
New Clues to Lupus' Link With Heart Disease
Date:2/26/2010

Antibodies could play key role, study finds

FRIDAY, Feb. 26 (HealthDay News) -- An increase in certain types of immune system antibodies may contribute to the development of heart disease in people with active lupus, a new study finds.

Lupus is an autoimmune illess in which the immune system creates antibodies that attack the body's own cells, causing widespread inflammation that results in damage to tissue and organs, including the heart, kidneys, brain, blood, skin and joints.

In this study, Australian and British researchers found that patients with active lupus had significantly increased levels of autoantibodies to fat-binding proteins than those with less active disease. The increase in these proteins -- anti-apolipoprotein (anti-Apo A-I), anti-high-density lipoprotein (anti-HDL) and anti-C-reactive protein (anti-CRP) -- may contribute to the development of atherosclerosis (hardening of the arteries) and increase the risk of cardiovascular disease.

The study appears in the March issue of the journal Arthritis & Rheumatism.

This is an important finding, but "measuring antibodies to ApoA-I, HDL or CRP in (lupus) patients has not yet reached the point where it can be used routinely to identify risk of accelerated atherosclerosis," Dr. Bevra Hahn, of the David Geffen School of Medicine at the University of California, Los Angeles, wrote in an accompanying editorial.

"As risk prediction models emerge over the next few years, these antibodies may be included along with other predisposing variables," she added.

As many as 1.5 million people in the United States and close to five million people worldwide have some form of lupus, according to the Lupus Foundation of America.

More information

The U.S. National Institute of Arthritis and Musculoskeletal and Skin Diseases has more about lupus.



-- Robert Preidt



SOURCE: Arthritis & Rheumatism, news release, Feb. 25, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Investigators uncover intriguing clues to why persistent acid reflux sometimes turns into cancer
2. Online Epidemic Gives Clues to Bird Flu Spread
3. New knock-out gene model provides molecular clues to breast cancer
4. New clues to breast cancer development in high-risk women
5. Clues to Cell Death Could Fight Disease
6. Genes Give Clues to Newborn Lung Disease
7. Mouse Study Gives Clues to Colitis
8. VivoMetrics LifeShirt Going to South Pole to Uncover Clues to High-Altitude Illness
9. Protein Gives Clues to Pancreatic Cancer
10. A longer-living, healthier mouse that could hold clues to human aging
11. Clues to ensuring anti-HIV drugs are taken in Africa
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... PurhealthRX ... CBD Oil utilizing Purzorb™ technology. Applying the Purzorb™process to full spectrum CBD oil will ... and providing a CBD form that can be easily incorporated into liquid products, while ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Apple Rehab ... services, staged a mock evacuation of the facility as part of a disaster drill ... Department, Echo Hose EMS and Shelton City Emergency Manager, as well as the ...
(Date:10/13/2017)... ... 13, 2017 , ... Ellevate Network, the leading network for professional women, brought ... gender equality at their inaugural Summit in New York City in June. The event ... audience of over 3 million. To watch the Mobilize Women video, click here ...
(Date:10/13/2017)... ... 13, 2017 , ... Talented host, actor Rob Lowe, is ... a new episode of "Success Files," which is an award-winning educational program broadcasted ... each subject in-depth with passion and integrity. , Sciatica occurs when the sciatic ...
(Date:10/13/2017)... ... 2017 , ... “America On The Brink”: the Christian history of the United ... the creation of published author, William Nowers. Captain Nowers and his wife, Millie, ... spent thirty years in the Navy. Following his career as a naval aviator ...
Breaking Medicine News(10 mins):
(Date:9/22/2017)... 2017  As the latest Obamacare repeal effort moves ... (R-LA) and Lindsey Graham (R-SC) medical ... device industry is in an odd place.  The industry ... excise tax on medical device sales passed along with ... patients, increased visits and hospital customers with the funding ...
(Date:9/19/2017)... ZirMed Inc ., a recognized leader in cloud-based revenue cycle ... ranked #1 by its users for the seventh consecutive year ... ZirMed was recognized as the top-ranked end-to-end revenue cycle management ... 200 beds and holds one of the longest #1 ranking ... ...
(Date:9/13/2017)... has been named the official orthopedic and sports medicine ... 2018 College Football Playoff (CFP) National Championship to be played ... Atlanta, Georgia . OrthoAtlanta is proud to be ... many activities leading up to, and including the national championship ... OrthoAtlanta serves ...
Breaking Medicine Technology: