Navigation Links
New Clues to Lupus' Link With Heart Disease
Date:2/26/2010

Antibodies could play key role, study finds

FRIDAY, Feb. 26 (HealthDay News) -- An increase in certain types of immune system antibodies may contribute to the development of heart disease in people with active lupus, a new study finds.

Lupus is an autoimmune illess in which the immune system creates antibodies that attack the body's own cells, causing widespread inflammation that results in damage to tissue and organs, including the heart, kidneys, brain, blood, skin and joints.

In this study, Australian and British researchers found that patients with active lupus had significantly increased levels of autoantibodies to fat-binding proteins than those with less active disease. The increase in these proteins -- anti-apolipoprotein (anti-Apo A-I), anti-high-density lipoprotein (anti-HDL) and anti-C-reactive protein (anti-CRP) -- may contribute to the development of atherosclerosis (hardening of the arteries) and increase the risk of cardiovascular disease.

The study appears in the March issue of the journal Arthritis & Rheumatism.

This is an important finding, but "measuring antibodies to ApoA-I, HDL or CRP in (lupus) patients has not yet reached the point where it can be used routinely to identify risk of accelerated atherosclerosis," Dr. Bevra Hahn, of the David Geffen School of Medicine at the University of California, Los Angeles, wrote in an accompanying editorial.

"As risk prediction models emerge over the next few years, these antibodies may be included along with other predisposing variables," she added.

As many as 1.5 million people in the United States and close to five million people worldwide have some form of lupus, according to the Lupus Foundation of America.

More information

The U.S. National Institute of Arthritis and Musculoskeletal and Skin Diseases has more about lupus.



-- Robert Preidt



SOURCE: Arthritis & Rheumatism, news release, Feb. 25, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Investigators uncover intriguing clues to why persistent acid reflux sometimes turns into cancer
2. Online Epidemic Gives Clues to Bird Flu Spread
3. New knock-out gene model provides molecular clues to breast cancer
4. New clues to breast cancer development in high-risk women
5. Clues to Cell Death Could Fight Disease
6. Genes Give Clues to Newborn Lung Disease
7. Mouse Study Gives Clues to Colitis
8. VivoMetrics LifeShirt Going to South Pole to Uncover Clues to High-Altitude Illness
9. Protein Gives Clues to Pancreatic Cancer
10. A longer-living, healthier mouse that could hold clues to human aging
11. Clues to ensuring anti-HIV drugs are taken in Africa
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/27/2016)... ... May 27, 2016 , ... This campaign aims to ... which we as a society can control and change. , As nearly 795,000 Americans ... 40 seconds within the United States. Plus, with an estimated 129,000 of these people ...
(Date:5/27/2016)... ... May 27, 2016 , ... Aimed at nurses ... human interest stories, courtesy of leaders in the nursing and health care industry. ... from leading advocates and associations—namely Jones & Bartlett Learning. , Jones & Bartlett ...
(Date:5/26/2016)... ... , ... Despite last week’s media reports hinting at a June rate hike ... March 2017 for an interest rate increase, according to Rajeev Dhawan of the Economic ... Federal Open Market Committee (FOMC) dot charts are of interest to the press for ...
(Date:5/26/2016)... ... May 26, 2016 , ... Intalere, the healthcare industry leader ... its inaugural Member Conference at the Paris Hotel in Las Vegas, Nev., May ... of America’s healthcare providers. , The conference was highlighted by the announcement of ...
(Date:5/26/2016)... ... May 26, 2016 , ... The Woodlands at John Knox ... new model of care for living and healing, celebrated its grand opening, today. The ... a Real Home provided by Empowered Staff. , “This is an incredibly fulfilling time ...
Breaking Medicine News(10 mins):
(Date:5/24/2016)... May 24, 2016  Diana Russell suffers from a ... from the inside out.  This disease has put her ... her children and grandchildren to leave her home.  Because ... family cannot haul the wheelchair.  So if there is ... and Diana is left to wait for the bus. ...
(Date:5/24/2016)... LAWRENCE, Mass. , May 24, 2016  NxStage ... medical technology company focused on advancing renal care, today ... Officer, plans to participate in the following schedule of ... will be made available at http://ir.nxstage.com/ . ... Jefferies Healthcare Conference NY, NY           Friday, ...
(Date:5/24/2016)... 2016  Joe Marziani has joined VMS BioMarketing as senior vice president of sales, ... his new role, Marziani will lead the company,s business development and sales team, exploring ... Photo - http://photos.prnewswire.com/prnh/20160523/371089 ... ... ...
Breaking Medicine Technology: