Navigation Links
New Clues to Link Between Fatty Diet, Colon Cancer
Date:3/16/2012

THURSDAY, March 15 (HealthDay News) -- Researchers say they've discovered clues about how a fatty diet increases the risk of colon cancer.

"There have always been questions about why things like diet and obesity are independent risk factors for colon cancer. This study suggests how and why high-fat diets are linked to colon cancer," lead author Carmen Sapienza, a professor of pathology in Temple University's Fels Institute for Cancer Research and Molecular Biology, said in a university news release.

He and his colleagues examined healthy colon tissue from colon cancer patients and found that epigenetic marks on genes involved in breaking down carbohydrates, fats and amino acids -- which are all common in a fatty Western diet -- seem to have been retrained.

Epigenetic marks are chemical modifications that act as on/off switches for many genes, according to the release.

"These foods are changing the methylation patterns on a person's insulin genes so that they express differently, pumping out more insulin than the body requires," Sapienza explained. "In people that have colon cancer, their glucose metabolic pathways and insulin-signaling pathways are running at completely different levels than people who don't have colon cancer."

Cancer cells "love" insulin and studies have shown that tumors feed off insulin, Sapienza noted.

Most cases of colon cancer occur in people 50 and older, and it is unclear when these genetic changes begin. If such changes can be detected in other healthy tissues in the body, it might be possible to use blood or saliva tests to determine a person's colon cancer risk or diagnose the disease, Sapienza suggested.

The study was published in the March issue of the journal Cancer Prevention Research.

More information

The American Cancer Society has more about colorectal cancer.

-- Robert Preidt

SOURCE: Temple University, news release, March 7, 2012


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Tiny fruit fly could offer big clues in fight against obesity, researcher says
2. Chickens May Provide Clues to Color Vision
3. New clues found linking larger animals to colder climates
4. New Clues to Lupus Link With Heart Disease
5. Blood Gives Clues to Executive Thinking Problems
6. Clues to pregnancy-associated breast cancer found
7. Clues Found to How Different Flu Vaccines Work
8. New Clues to Pregnancy-Associated Breast Cancer
9. Scientists Find Clues to How the Body Fights Off HIV
10. More Clues Emerge on How HIV Infects Women
11. Lab that probes genetic clues to disease is poised for major expansion
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Clues to Link Between Fatty Diet, Colon Cancer
(Date:6/27/2016)... Viejo, California (PRWEB) , ... June 27, 2016 , ... ... are fully customizable inside of Final Cut Pro X," said Christina Austin - CEO ... another unique style. Final Cut Pro X users can now reveal the ...
(Date:6/27/2016)... ... June 27, 2016 , ... ... strategic partnership with Connance, a healthcare industry leader providing predictive analytics to ... technology combine to provide health systems, hospitals and ambulatory surgical centers with ...
(Date:6/27/2016)... Overland Park, KS (PRWEB) , ... June 27, 2016 , ... ... leader in retailers of Eyeglasses . , Millions of individuals in the United ... life, eyeglasses have become a way to both correct vision and make a fashion ...
(Date:6/26/2016)... ... 26, 2016 , ... On June 10-11, 2016, A Forever Recovery, a holistic ... World’s Longest Breakfast Table in Battle Creek, MI, where the rehabilitation facility is located. ... some of the world’s leading providers of cereal and other breakfast foods. Its residents ...
(Date:6/26/2016)... ... June 26, 2016 , ... PawPaws brand pet supplements ... that was developed to enhance the health of felines. The formula is all-natural and ... main herbs in the PawPaws Cat Kidney Support Supplement Soft Chews are ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... -- Jazz Pharmaceuticals plc (Nasdaq: JAZZ ) ... Improvements Act of 1976, as amended ("HSR"), with respect ... Nasdaq: CPXX ) expired effective June 24, ... As previously announced on May 31, 2016, Jazz Pharmaceuticals ... which Jazz Pharmaceuticals has commenced a tender offer for ...
(Date:6/24/2016)... HILL, N.C. , June 24, 2016 /PRNewswire/ ... healthcare decisions and regulators/payers have placed more emphasis ... new environment, patient support programs in the pharmaceutical ... for patients, medications. Consequently, pharmaceutical companies are focusing ... ensure they are providing products and services that ...
(Date:6/24/2016)... CAMBRIDGE, Mass. , June 24, 2016 /PRNewswire/ ... the Spaulding Rehabilitation Network,s Dean Center for ... of Physical Medicine and Rehabilitation, MIT Hacking Medicine, ... Center for Innovation, today announced the five finalists ... Hackathon for Lyme disease.  More than 100 scientists, ...
Breaking Medicine Technology: