Navigation Links
New Clues Shed Light on Sperm Function, Male Fertility

Researchers uncover key proteins in mice that could lead to new birth control for men

WEDNESDAY, April 28 (HealthDay News) -- Two proteins in a family of proteins called PLA2s play a vital role in sperm function and fertility in mice, say two teams of researchers.

The findings could improve understanding of male infertility and lead to new types of male birth control and treatments for infertility.

In one study, Japanese researchers found that the protein sPLA2-III is expressed in an area of the testis called the proximal epididymal epithelium. Male mice that lacked the protein had low levels of fertility because their sperm did not mature properly, which resulted in decreased motility and decreased ability to fertilize eggs.

In the second study, French researchers found that male mice that lacked the protein group X secreted PLA2 (also known as mGX) produced smaller litters than normal, and that sperm from mGX-deficient mice were not efficient at fertilizing eggs.

The studies were published April 26 in the Journal of Clinical Investigation.

More information

The American Academy of Family Physicians has more about male infertility.

-- Robert Preidt

SOURCE: Journal of Clinical Investigation, news release, April 26, 2010

Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1

Related medicine news :

1. Ovarian cancer study offers vital clues for new therapies
2. Change in breast density over time provides clues about breast cancer risk
3. Lab that probes genetic clues to disease is poised for major expansion
4. More Clues Emerge on How HIV Infects Women
5. Scientists Find Clues to How the Body Fights Off HIV
6. New Clues to Pregnancy-Associated Breast Cancer
7. Clues Found to How Different Flu Vaccines Work
8. Clues to pregnancy-associated breast cancer found
9. Blood Gives Clues to Executive Thinking Problems
10. New Clues to Lupus Link With Heart Disease
11. New clues found linking larger animals to colder climates
Post Your Comments:
(Date:6/25/2016)... ... June 25, 2016 , ... Austin residents seeking Mohs surgery services, can now ... and to Dr. Russell Peckham for medical and surgical dermatology. , Dr. Dorsey brings ... The selective fellowship in Mohs Micrographic Surgery completed by Dr. Dorsey was under the ...
(Date:6/25/2016)... Oklahoma (PRWEB) , ... June 25, 2016 , ... ... both athletes and non-athletes recover from injury. Recently, he has implemented orthobiologic procedures ... Oklahoma City area —Johnson is one of the first doctors to perform the ...
(Date:6/24/2016)... ... 24, 2016 , ... June 19, 2016 is World Sickle Cell Observance Day. ... the benefits of holistic treatments, Serenity Recovery Center of Marne, Michigan, has ... , Sickle Cell Disease (SCD) is a disorder of the red blood cells, which ...
(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San Diego, CA is excited ... To Recovery® program to drive cancer patients to and from their cancer treatments. ... highest quality of life and ongoing independence. Getting to and from medical treatments ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... Investment Group (TGIG), has initiated cultivation and processing operations at its production facility, ... Pahrump, Nevada. , Puradigm is the manufacturer of a complete system of proactive ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 2016  Arkis BioSciences, a leading innovator in ... durable cerebrospinal fluid treatments, today announced it has ... is led by Innova Memphis, followed by Angel ... investors.  Arkis, new financing will accelerate the commercialization ... release of its in-licensed Endexo® technology. ...
(Date:6/23/2016)... June 23, 2016 Any dentist who has made ... the current process. Many of them do not even offer ... difficulties and high laboratory costs involved. And those who ARE ... at such a high cost that the majority of today,s ... Dr. Parsa Zadeh , founder of Dental Evolutions Inc. ...
(Date:6/23/2016)... INDIANAPOLIS , June 23, 2016 Roche ... received 510(k) clearance for its Elecsys BRAHMS PCT (procalcitonin) ... severe sepsis or septic shock. With this clearance, Roche ... provide a fully integrated solution for sepsis risk assessment ... associated with bacterial infection and PCT levels in blood ...
Breaking Medicine Technology: