Navigation Links
New Classification Proposed for Stomach Cancers
Date:10/2/2009

Categorizing by pathway, not cell type, may lead to better treatments, researchers say,,

FRIDAY, Oct. 2 (HealthDay News) -- A new way to classify stomach cancers could lead to more effective treatments and improved long-term survival for people with the disease, researchers say.

For a study published online Oct. 1 in PLoS Genetics, the researchers analyzed 301 stomach tumors from people in Australia, Singapore and Great Britain, classifying the cancers according to the signaling pathways the tumors use to grow and spread. Currently, stomach cancers are classified by cell type or structure.

"We identified three oncogenic pathways that were activated in over 70 percent of the gastric tumors we examined," lead author Chia Huey Ooi, a research fellow at the Duke-National University of Singapore Graduate Medical School, said in a Duke news release. "We also found that combinations of these pathways are significantly related to patient survival."

Less than a quarter of stomach cancer patients live longer than five years after surgery. The disease is resistant to chemotherapy, and new biologic-based treatments have not proven very effective.

Using this new system, doctors could classify patients according to the pathway profile of their tumor and design treatments to interrupt the signals used by the pathways.

"These findings may give us the first way to truly offer our gastric cancer patients personalized medicine," the study's senior author, Dr. Patrick Tan, also from the Duke-NUS medical school and the Genome Institute of Singapore, said in the news release.

More information

The American Cancer Society has more about stomach cancer.



-- Robert Preidt



SOURCE: Duke University, news release, Oct. 1, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. American Academy of Dermatology Commends Reclassification of Tanning Beds as Carcinogenic
2. DC Government Renews Certified Business Enterprise Classification to Language Interpretation and Translation Firm
3. Xanodynes New Drug Application for the Treatment of Heavy Menstrual Bleeding (Menorrhagia) Accepted for Filing with a Priority Review Classification
4. New Directions in Angioedema: A Focus on Pathogenesis and Classification
5. Cyberonics Provides Business Update Based on Final Ambulatory Payment Classification Rate Change Announcement by CMS
6. STAAR Surgicals Collamer(R) IOL and Elastimide(R) IOL Each Recognized with New Technology Intraocular Lens Classification
7. Tarpinian: Misclassification is Theft
8. Proposed Medicare Changes Will Increase Costs to Government, Decrease Options for Patients
9. RetireSafe to Senate: Stop Proposed Rationing of High-Quality Hospital Care - Medicare Needs More Physician Hospitals
10. Oxygen Biotherapeutics, Inc. Posts Blog by CEO Chris Stern on Proposed Reverse Split
11. ACLA Opposes Proposed LabTax
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/10/2016)... ... February 10, 2016 , ... United ... Nesbitt as the latest addition to its growing list of Partner Firms. ... the Southeast, from Orlando to Huntsville and in between. , Harnessing the experience ...
(Date:2/10/2016)... ... February 10, 2016 , ... Pediatric therapists are challenged ... Research shows that the Goal Attainment Scale (GAS) captures 20% more change in ... learn more about the Goal Attainment Scale, Education Resources Inc. is offering a ...
(Date:2/10/2016)... ... February 10, 2016 , ... IDEX Health & Science, ... stainless steel (PLS) columns combine the strength of traditional stainless steel with the ... biological samples while operating at ultra-high pressures of 20,000 psi. The higher operating ...
(Date:2/10/2016)... , ... February 10, 2016 , ... Anxiety of older ... the start of Medicare Part D a decade ago, according to The Senior ... older adults on how they are coping with rapidly rising costs. “The implications ...
(Date:2/10/2016)... ... February 09, 2016 , ... ... the cause of injury may be one of many possible sources: sports, car ... Continuing Education Course , Mastering Rehab Solutions for the Complexities of Concussions ...
Breaking Medicine News(10 mins):
(Date:2/10/2016)... Feb. 10, 2016  Silicon Biosystems Menarini Inc., ... that help uncover the biological complexities of disease ... a developer of innovative technologies for genomics research, ... aimed at enabling translational researchers to obtain high-quality ... hundred tumor and normal cells in an optimized ...
(Date:2/10/2016)... India , February 10, 2016 ... a new market research report "Pharmaceutical Packaging Equipment Market ... Wrapping, Labeling & Serialization), by Product Type (Tablet, Powder, ... 2020", published by MarketsandMarkets, studies the global market during the ... expected to grow at a CAGR of 6.9% during ...
(Date:2/10/2016)... Feb. 9, 2016 On Tuesday, ... (FDA) met with its Arthritis Advisory Committee ... of Johnson & Johnson,s Remicade and most ... in the U.S. The Biologics Prescribers Collaborative ... - Alliance for Patient Access, American Association ...
Breaking Medicine Technology: