Navigation Links
New Classification Proposed for Stomach Cancers
Date:10/2/2009

Categorizing by pathway, not cell type, may lead to better treatments, researchers say,,

FRIDAY, Oct. 2 (HealthDay News) -- A new way to classify stomach cancers could lead to more effective treatments and improved long-term survival for people with the disease, researchers say.

For a study published online Oct. 1 in PLoS Genetics, the researchers analyzed 301 stomach tumors from people in Australia, Singapore and Great Britain, classifying the cancers according to the signaling pathways the tumors use to grow and spread. Currently, stomach cancers are classified by cell type or structure.

"We identified three oncogenic pathways that were activated in over 70 percent of the gastric tumors we examined," lead author Chia Huey Ooi, a research fellow at the Duke-National University of Singapore Graduate Medical School, said in a Duke news release. "We also found that combinations of these pathways are significantly related to patient survival."

Less than a quarter of stomach cancer patients live longer than five years after surgery. The disease is resistant to chemotherapy, and new biologic-based treatments have not proven very effective.

Using this new system, doctors could classify patients according to the pathway profile of their tumor and design treatments to interrupt the signals used by the pathways.

"These findings may give us the first way to truly offer our gastric cancer patients personalized medicine," the study's senior author, Dr. Patrick Tan, also from the Duke-NUS medical school and the Genome Institute of Singapore, said in the news release.

More information

The American Cancer Society has more about stomach cancer.



-- Robert Preidt



SOURCE: Duke University, news release, Oct. 1, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. American Academy of Dermatology Commends Reclassification of Tanning Beds as Carcinogenic
2. DC Government Renews Certified Business Enterprise Classification to Language Interpretation and Translation Firm
3. Xanodynes New Drug Application for the Treatment of Heavy Menstrual Bleeding (Menorrhagia) Accepted for Filing with a Priority Review Classification
4. New Directions in Angioedema: A Focus on Pathogenesis and Classification
5. Cyberonics Provides Business Update Based on Final Ambulatory Payment Classification Rate Change Announcement by CMS
6. STAAR Surgicals Collamer(R) IOL and Elastimide(R) IOL Each Recognized with New Technology Intraocular Lens Classification
7. Tarpinian: Misclassification is Theft
8. Proposed Medicare Changes Will Increase Costs to Government, Decrease Options for Patients
9. RetireSafe to Senate: Stop Proposed Rationing of High-Quality Hospital Care - Medicare Needs More Physician Hospitals
10. Oxygen Biotherapeutics, Inc. Posts Blog by CEO Chris Stern on Proposed Reverse Split
11. ACLA Opposes Proposed LabTax
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/6/2016)... , ... December 06, 2016 , ... TopConsumerReviews.com recently gave ... Mobility Scooters . , Mobility Scooters give freedom to people who need help getting ... others may be facing a long period of rehabilitation after an illness or accident. ...
(Date:12/5/2016)... ... 2016 , ... What: Shriners Hospitals for Children, with the help of Dimension ... using a video monitor and web-enabled camera. Santa visits with children through Dimension Data’s ... Christmas Wonderland, which is where the video connection to the North Pole will stream. ...
(Date:12/5/2016)... (PRWEB) , ... December 06, 2016 , ... For many ... Lithuanian poetry , both thick and thin. The beauty of the Lithuanian language ... Trafford Publishing). , In this poetry book, Zubinas lyrically explores all aspects of a ...
(Date:12/5/2016)... ... December 05, 2016 , ... ... leading global lifestyle design firm kathy ireland® Worldwide for five additional years, announced ... entered into an exclusive licensing agreement three years ago to design and develop ...
(Date:12/5/2016)... (PRWEB) , ... December 05, ... ... strategic interoperability, today announced that the company will provide alerting technology to ... has been recently awarded $1.7 million in federal funds as the sole ...
Breaking Medicine News(10 mins):
(Date:12/5/2016)... Fla. , Dec. 5, 2016  Breckenridge ... into a multi-product marketing agreement with development and ... injectable products. Under the terms of this agreement, ... its label in the United States ... and one tentatively-approved ANDA. The products cover a ...
(Date:12/5/2016)... , December 5, 2016 According to a new ... and by Application - Global Opportunity Analysis and Industry Forecast, 2014 - 2022", ... expected to reach $5,255 million by 2022, growing at a CAGR of 6.4% ... more than four-fifths share. Continue Reading ... ...
(Date:12/5/2016)... Sanovas, Inc., a life science asset holding company ... wholly owned subsidiary, Intubation Science, Inc., and its LightSpeed Intubation ... http://photos.prnewswire.com/prnh/20161202/445251LOGO   ... Sanovas, Inc. ... There are over 40 million Endotracheal Intubations performed annually ...
Breaking Medicine Technology: