Navigation Links
New Class of Drugs Might Treat Many Conditions
Date:5/9/2008

Vaptans ease painful periods, glaucoma, depression and many other diseases, researchers say

FRIDAY, May 9 (HealthDay News) -- A new class of drugs called vaptans may be able to treat a wide variety of conditions including painful periods, brain hemorrhage, psychotic disorders and glaucoma, Belgian researchers report.

Vaptans, short for vasopressin-receptor antagonists, work by targeting the vasopressin hormone system, which plays an important role in controlling blood and water volume in the body. These drugs, which can be taken orally or intravenously, block the action of vasopressin, according to the report in the May 10 issue of The Lancet.

In the report, Dr. Guy Decaux, from Erasmus University Hospital in Brussels, and his colleagues reviewed the current state of vaptans, of which there are several subclasses, that have been development or are under development.

Among these new drugs are relcovaptan, which has shown initial positive results in treating painful periods, as well as Raynaud's disease, which affects blood flow to the arms and legs, and tocolysis, (premature labor, leading to premature birth).

Another subclass of vaptans that include mozavaptan, lixivaptan, satavaptan and tolvaptan are diuretics, which remove water from the body, while maintaining the body's electrolyte, or salt mineral, balance. Other diuretics don't maintain the body's electrolyte balance, the researchers noted.

Some vaptans can be used to treat hyponatremia, which is a life-threatening loss of salt. Currently, conivaptan is the only vaptan approved by the U.S. Food and Drug Administration for treating hyponatremia.

Other vaptans in development might be used to treat kidney failure, diabetic nephropathy, a progressive kidney disease associated with diabetes, cirrhosis and depression, the researchers wrote.

In addition, early studies of vaptans for treating glaucoma, Menire's disease-- an inner ear condition affecting hearing and balance -- brain hemorrhage, and small-cell lung cancer, have had promising results, Decaux's team noted.

Despite these promising results, one expert isn't ready to called vaptans a miracle cure yet.

"This is nice review of an emerging class of drugs," said Dr. Gary S. Francis, director of the coronary intensive care unit at the Cleveland Clinic. "But it is a little early to know if they will prove to be highly useful."

More information

For more on conivaptan, visit the U.S. Food and Drug Administration.



SOURCES: Gary S. Francis, M.D., director, coronary intensive care unit, Cleveland Clinic; May 10, 2008, The Lancet


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Kingfisher Healthcare (KFH) Achieves World Class Quality Platform
2. ADDA Kicks Off AD/HD Awareness Campaign with Four Regional Conferences Beginning Sept. 29 and Series of Fall Teleclasses
3. A classic method for modeling skin cancer is featured in Cold Spring Harbor Protocols
4. First Circuit Court of Appeals Rules Against Philip Morris in Lights Class Action
5. Theater Classes Help Docs Bedside Manners
6. Tarpinian: Misclassification is Theft
7. New class of RNA molecules may be important in human cancer
8. Instrumentation Laboratory Named Top of Class by Respiratory Care Managers
9. Consumer Group: Hillary Clintons Mandatory Health Insurance Purchase Plan is an Act of War on the Middle Class Family That Cant Afford $12k Policy
10. SATELLITE BROADCAST: Consumer Group Says Hillary Clintons Mandatory Health Insurance Plan is an Act of War on the Middle Class that Cant Afford $12k Policy
11. Law Offices of Howard G. Smith Announces Class Action Lawsuit Against LCA-Vision Inc.
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Class of Drugs Might Treat Many Conditions
(Date:5/5/2016)... ... 05, 2016 , ... LELO has discovered many people are insecure ... out via email, social media and on the Volonté blog seeking advice about how ... masturbate ‘normal’ or ‘correct’?” , While some methods are more common than others, there ...
(Date:5/5/2016)... Ridgeland, MS (PRWEB) , ... May 05, 2016 ... ... life-threatening medical conditions and Make-A-Wish grants the most heartfelt wishes of these children. ... long rounds of medical treatment. President and CEO of Make-A-Wish Mississippi, Brent ...
(Date:5/5/2016)... ... May 05, 2016 , ... ... Association (SACA) is slated to host the 2016 National SACA Leadership Conference on ... SACA national officers and chapter officers to come together and develop skills to ...
(Date:5/5/2016)... ... 05, 2016 , ... Tim Dieter has announced the latest ... Dubuque, IA. The current campaign fundraises for Veteran’s Freedom Center on behalf of ... Freedom Center may now be made here: http://www.veteransfreedomcenter.com/donate/ . , Veteran’s Freedom ...
(Date:5/5/2016)... (PRWEB) , ... May 05, 2016 , ... ... to provide focused resources for veterinary professionals across the United States. The whole ... the lives of their patients and giving dog, cat and horse owners’ peace ...
Breaking Medicine News(10 mins):
(Date:5/5/2016)... , May 5, 2016 ... of the  "Europe Thalassaemia Market and Competitive ... offering.       (Logo: http://photos.prnewswire.com/prnh/20160330/349511LOGO ... Thalassaemia Market and Competitive Landscape Highlights - ... products, Thalassaemia epidemiology, Thalassaemia market valuations and ...
(Date:5/4/2016)... 2016  Compass Diversified Holdings (NYSE: CODI ... of leading middle market businesses, announced today its consolidated ... 2016. First Quarter 2016 Highlights , ... or "Cash Flow") of $13.6 million for the first ... $15.0 million for the first quarter of 2016; ...
(Date:5/4/2016)... 4, 2016  It,s time for an upgrade. There are many medical recorders on ... inch LCD, the illustrious DVMAXX HD  offers unparalleled connectivity and functionality.  Ampronix  is ... world class manufacturer of innovative technology.  Photo - http://photos.prnewswire.com/prnh/20160503/363416 ... ... ...
Breaking Medicine Technology: