Navigation Links
New Chemo Regimen May Benefit Ovarian Cancer Patients
Date:9/20/2009

Dose-dense treatment improved survival, but too toxic for some: study

SUNDAY, Sept. 20 (HealthDay News) -- Dose-dense chemotherapy improves survival in women with advanced ovarian cancer, Japanese researchers say.

Currently, paclitaxel and carboplatin given every three weeks is considered standard first-line chemotherapy for advanced epithelial ovarian cancer. However, dose-dense weekly treatment with paclitaxel is seen as a way to increase progression-free and overall survival in these patients, according to the new study findings.

This phase 3 study of 637 women compared the two approaches. The participants had advanced epithelial ovarian cancer, fallopian tube cancer, or primary peritoneal cancer.

The 320 patients in the conventional regimen group received six cycles of paclitaxel (180 milligrams per meter squared; three-hour intravenous infusion). The 317 patients in the dose-dense group received paclitaxel (80 milligrams per meter squared; one-hour intravenous infusion) on days one, eight and 15. Both groups received carboplatin on day one of a 21-day cycle.

The patients in the dose-dense group had longer median progression-free survival than those in the standard treatment group (28 months versus 17 months), and longer overall survival at three years (72 percent versus 65 percent). This means that women in the dose-dense group had a 29 percent lower risk of cancer progression and a 25 percent lower risk of death, the authors explained.

Toxicity forced 113 patients in the dose-dense group and 69 patients in the conventional therapy group to stop treatment, the researchers noted. Severe anemia occurred in 214 patients (69 percent) in the dose-dense group and in 137 (44 percent) of the standard therapy group.

The survival benefits seen in the dose-dense group are rare in patients with advanced ovarian cancer, and this regimen offers a new treatment option for women with advanced e
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Chemobrain -- the flip side of surviving cancer
2. Yeast unravels effects of chemotherapy drugs
3. Chemotherapy Linked to Sleep-Wake Cycle Disruptions
4. Blood Thinner May Prevent Chemo-Related Clots
5. Chemotherapy for breast cancer is associated with disruption of sleep-wake rhythm in women
6. JNCI news brief: Melanosome dynamics and sensitivity of melanoma cells to chemotherapy
7. Chemo Plus Palliative Care Reaps Benefits
8. Stray Breast Cancer Cells Yield to Post-Op Chemo
9. JNCI news brief: Antibody linked to chemotherapy drug inhibits ovarian cancer in lab
10. Radiation Plus Chemo a Good Option in Lung Cancer
11. Oral Chemotherapy Offers Patients a More Convenient, Less Invasive Treatment Option
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Chemo Regimen May Benefit Ovarian Cancer Patients 
(Date:5/25/2015)... May 25, 2015 24Hr HomeCare is ... Tyner Brenneman-Slay, Co-Founder & COO, and Ryan Iwamoto, Co-Founder ... Entrepreneur Of The Year® 2015 Awards in Greater Los ... who demonstrate excellence in innovation, financial performance, and a ... at the core of the ongoing success of our ...
(Date:5/25/2015)... (PRWEB) May 25, 2015 Stanley ... awards for design of the wastewater treatment ... Iowa.    The project received a National Recognition Award from the ... Award from ACEC – Iowa. Competitions held by ... , The $50.2 million expansion is Iowa City’s largest ...
(Date:5/25/2015)... Join Fiona's Soccer Camp at Novato High School's Tibi ... National Player, Fiona O'Sullivan will be on site to run ... coaching style. Fiona has three camps running this summer in ... Lynwood Elmentary School (June 15-19) and Hill Recreation Center (June ... 2015 - 1:00-3:00pm. Bring a Soccer Ball, Cleats and a ...
(Date:5/25/2015)... White Plains, NY (PRWEB) May 25, 2015 ... LEED AP, principal of PBDW Architects in New York City, ... which is part of the hospital’s ongoing Legacy Lobby Lecture ... campus in White Plains. White is the great grandson of ... firm responsible for the design of Burke’s campus 100 years ...
(Date:5/24/2015)... May 24, 2015 The Rolling Stones ... 24th in San Diego at Petco Park. This iconic ... On May 20th, they had a warmup show in ... preview show in Los Angeles, this beloved band not only ... played fan favorites such as "Jumping Jack Flash," "Moonlight ...
Breaking Medicine News(10 mins):Health News:24Hr HomeCare Co-Founders Named Finalists for EY Entrepreneur of the Year 2015 Awards 2Health News:Stanley Consultants’ Expansion of Iowa City Wastewater Treatment Plant Wins National Award 2Health News:Stanley Consultants’ Expansion of Iowa City Wastewater Treatment Plant Wins National Award 3Health News:US Sports Camps and Nike Soccer Camps Offer Complimentary Instructional Clinic with Fiona's Soccer Camp 2Health News:Burke Rehabilitation Hospital Welcomes Architect Samuel White, Descendant of McKim, Mead and White, for Legacy Lobby Lecture 2Health News:Burke Rehabilitation Hospital Welcomes Architect Samuel White, Descendant of McKim, Mead and White, for Legacy Lobby Lecture 3Health News:The Rolling Stones Tickets in San Diego, Orlando, Minneapolis, Dallas, Pittsburgh, Indianapolis, Atlanta, Detroit, Milwaukee, Kansas City, Columbus, Nashville & Raleigh 2
... another step closer to understanding why some people ... published in the new online open access journal ... enable more accurate prediction of the risk of ... (a pathological score given to prostate cancer based ...
... Wisconsin-based Fi-Med,Management, Inc. announced last week the acquisition ... in Utah and southern California., (Logo: ... 28, 2007, comes at the confluence of,two goals: ... efficient,technologies on board for their clients in an ...
... allergy symptoms report a high incidence of Irritable Bowel ... IBS according to a study published this month in ... of the American Collegeof Allergy, Asthma and Immunology. , ... Center,s Dr. Mary C. Tobin and colleagues found the ...
... higher chances of cardiovascular trouble during 2006 World Cup matches, ... plan on watching the Super Bowl on Sunday, you might ... a bad call, especially if you have known risk factors ... sports fans are watching their team play in a big ...
... Mylan Inc. (NYSE: MYL ),today announced that in ... declared an initial quarterly dividend of $15.53,per share (based on ... $1,000.00 per share and the time period from the date ... to holders of,preferred stock of record as of February 1, ...
... Jan. 30 Sports pundits across the country have,been ... the perfect,1972 Dolphins all year. Now, a New York ... trials to determine which,of the two teams is superior., ... the cardiovascular,therapy studies he writes and reviews, Dr. Jonathan ...
Cached Medicine News:Health News:Study reveals improved prediction of prostrate cancer 2Health News:Super Bowl Fans Should Heed Heart Risk Finding 2Health News:Super Bowl Fans Should Heed Heart Risk Finding 3Health News:Statistical Bowl - How the '07 Patriots and the '72 Dolphins Match Up 2Health News:Statistical Bowl - How the '07 Patriots and the '72 Dolphins Match Up 3
(Date:5/22/2015)... , May 22, 2015 The leading ... $13 billion global cardiac rhythm management device market ... found that Medtronic, St. Jude Medical, Boston Scientific ... of this market segment. The healthcare market research ... , uses 2015 as a base year, providing ...
(Date:5/22/2015)... ROCKVILLE, Md. , May 22, 2015 /PRNewswire/ ... "RegeneRx") today announced a peer-reviewed publication of the ... study evaluating RGN-259 (RegeneRx,s preservative-free eye drops) for ... Inc.,s controlled adverse environment (CAE ® ) model.  ... and the results, which were previously disseminated by ...
(Date:5/22/2015)... Research and Markets ( http://www.researchandmarkets.com/research/3rthk2/latest ... "Latest Regulations on Pharmaceutical International Multi-Center Clinical Trials ... This is first time in history, Chinese ... multi-center clinical trials of drugs in ... implemented on March 1, 2015. The guidance provides ...
Breaking Medicine Technology:Kalorama: Top Companies Dominate Cardiac Defibrillator Market 2Kalorama: Top Companies Dominate Cardiac Defibrillator Market 3Kalorama: Top Companies Dominate Cardiac Defibrillator Market 4Complete Data from RegeneRx Phase II Dry Eye Trial Published in Current Issue of Clinical Ophthalmology 2Complete Data from RegeneRx Phase II Dry Eye Trial Published in Current Issue of Clinical Ophthalmology 3Complete Data from RegeneRx Phase II Dry Eye Trial Published in Current Issue of Clinical Ophthalmology 42015 Regulations on Pharmaceutical International Multi-Center Clinical Trials in China 2
... The DataMate Laser Sheeted ... consists of laser-printable sheets ... wristband and laser labels ... The wristbands clear, fold-over ...
... DataMate Laser Sheeted Wristband ... of laser-printable sheets with ... and laser labels that ... wristbands clear, fold-over protective ...
... The DataMate system ... available between wristband and ... ClearImage surface for superior ... SuperBand® wristbands are durable ...
As part of a complete all-in-one system, Sentry LabelBand securely seals inexpensive paper labels inside a clear, adhesive shield. LabelBand provides easy and accurate bar code scanning and protectio...
Medicine Products: