Navigation Links
New Brain Stimulation Treatment May Offer Hope For Those With Treatment Resistant Depression
Date:10/13/2009

geon Istvan Takacs, MD and MUSC anesthesiologist Scott Reeves, MD.

Five patients were implanted with EpCS over the anterior frontal poles and the lateral prefrontal cortex bilaterally. Four separate paddle leads were then connected to two small generators surgically implanted in the upper chest area of the patient. The researchers individualized the treatment parameters for each patient to maximize the long-term antidepressant effects. They relied in part on input from the patients themselves who signaled positive mood changes when first stimulated. In general, their devices were set to periodically deliver electrical charges at intensities below the seizure threshold. The devices were never active at night. Only patients who failed to respond to several antidepressant treatments - including medications, psychotherapy, transcranial magnetic stimulation, vagus nerve stimulation or electroconvulsive therapy, were included in the study.

Patients were closely followed after the surgical implant and evaluated regularly using standard clinical ratings. After seven months, the average improvement was 54.9 percent based on the Hamilton Rating Scare for Depression and 60.1 percent on the Inventory of Depressive Symptoms Self Report . Three of the patients reached remission. One patient experienced a scalp infection that required removing the implants over the left hemisphere.

"These preliminary results are encouraging but not definitive," said Dr. Nahas. "Now that we have a proof of concept, we should aim at studying bilateral EpCS in larger placebo-controlled studies."

"The more sophisticated functions are on the surface of the brain" said Takacs. "We are trying to change the climate within the prefrontal cortex so it could exert more adaptive go
'/>"/>

SOURCE Medical University of South Carolina
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Draining away brains toxic protein to stop Alzheimers
2. Vision restoration therapy shown to improve brain activity in brain injured patients
3. Clinical depression linked to abnormal emotional brain circuits
4. Brain imaging reveals breakdown of normal emotional processing
5. Brain cells work differently than previously thought
6. Vaccine Stops Alzheimers Brain Tangles
7. Research may unlock mystery of autisms origin in the brain
8. Scientists Spot Brains Free Will Center
9. Free will takes flight: how our brains respond to an approaching menace
10. Alcoholics With Cirrhosis Have More Brain Damage
11. Brain Lesions Predict MS Progression
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/22/2014)... 2014--Women who are about to be released from prison ... if they are to successfully reintegrate into their communities ... study. , Almost half of all female prisoners are ... and most have multiple prison terms, mainly for drug-related ... Michael,s Hospital, conducted one-on-one interviews with women who were ...
(Date:9/22/2014)... September 22, 2014 BCC Research ... AUTOIMMUNE DISEASE DIAGNOSTICS: GLOBAL MARKETS, the global ... grow to nearly $13.1 billion by 2019, with ... 1.6%. Southern Asia holds the highest market ... factors and adoption of western lifestyles. , ...
(Date:9/22/2014)... the American College of Surgeons, Committee on Trauma, patients ... or level II trauma centers. Those centers have the ... , But 1 out of 3 major trauma patients ... centers or nontrauma centers, according to a new study ... Center for Injury Research and Policy at Nationwide Children,s ...
(Date:9/22/2014)... study by the Cancer Science Institute of Singapore ... (NUS) found that an increase in a gene ... directly implicated in acute myelogenous leukaemia (AML), increasing ... Associate Professor Chng Wee Joo, Deputy Director and ... of the National University Cancer Institute, Singapore, the ...
(Date:9/22/2014)... “I don’t belong there. My mind is fine. I ... of "My Inner Child Must Be Heard: From Despair to ... her six-decade battle with polio and subsequent struggles with clinical ... limitation is a way of life for Zalace. With over ... car accident in her history, she credits her positive outlook ...
Breaking Medicine News(10 mins):Health News:Involving female offenders in release planning can increase reintegration success 2Health News:Global Market for Autoimmune Disease Diagnostics to Reach Nearly $13.1 Billion in 2019; Southern Asia Holds the Highest Potential 2Health News:Global Market for Autoimmune Disease Diagnostics to Reach Nearly $13.1 Billion in 2019; Southern Asia Holds the Highest Potential 3Health News:New study finds 34 percent of severely injured patients undertriaged in the United States 2Health News:New study finds 34 percent of severely injured patients undertriaged in the United States 3Health News:Singapore researchers discover a gene that increases incidence of AML 2Health News:Polio Survivor Chronicles Journey in New Collection of Poems 2
... study finds , , THURSDAY, Sept. 27 (HealthDay News) -- ... trauma victims suffering from heavy blood loss and shock, ... the first scientific study showing the benefits of using ... Poloujadoff, an emergency physician at one of the University ...
... Mich., Sept. 27 Stryker,Corporation (NYSE: SYK ... resolution,with the United States Attorney,s office in Newark, ... practices in the,orthopaedic industry. The investigation began with ... 2005 that requested documents for the,period January 2002 ...
... ... supplemented, Unveils Campaign to Help Consumers Measure Their ... ... the creators of,the "Life ... supplemented" campaign set out to determine ... the launch of a,new Web site -- http://www.lifesupplemented.org -- ...
... NEWPORT NEWS, Va., Sept. 27 The Patient,Advocate ... patient services to tens of thousands of patients ... care because of financial or insurance,denials --announced this ... including health care policy leaders and medical professionals ...
... develop gene-based screens , , THURSDAY, Sept. 27 (HealthDay News) ... develop genetic tests that predict which patients will have ... a nonprofit organization dubbed the International Serious Adverse Events ... at drug-related liver toxicity and the other aimed at ...
... MANHATTAN, KAN. -- Workshops, online programs and databases are ... shares knowledge about the biosciences, food safety and animal ... of our food supply. , In the past 27 ... States and around the world have turned to Kansas ...
Cached Medicine News:Health News:Toxic Shock Drug Might Aid Trauma Victims 2Health News:Toxic Shock Drug Might Aid Trauma Victims 3Health News:Stryker Announces Resolution Related to March 2005 U.S. Department of Justice Subpoena 2Health News:Are You An AlphaWell or An OhWell? 2Health News:Patient Advocate Foundation Welcomes Leading Health Care Experts to Executive Board of Directors 2Health News:Patient Advocate Foundation Welcomes Leading Health Care Experts to Executive Board of Directors 3Health News:Drug Industry Seeks Tests to Spot Side Effect Risks 2Health News:Drug Industry Seeks Tests to Spot Side Effect Risks 3Health News:Professionals in bioscience, food-related industries turn to K-State 2Health News:Professionals in bioscience, food-related industries turn to K-State 3
(Date:9/19/2014)... HILL, N.C. , Sept. 19, 2014 ... to Best Practices, LLC with three issues he wanted ... , The use of external personnel (especially for secondary ... headcount in the face of increased workload , ... and better knowledge management , How to implement ...
(Date:9/19/2014)... , Sept. 19, 2014 ... used to inflate sales of brand drugs among ... D,  according to a new report  from ... Office of the Inspector General (OIG). Federal anti-kickback laws ... of goods that are subsidized by the federal ...
(Date:9/19/2014)... Sept. 19, 2014 /PRNewswire-iReach/ -- Market Research ... Industry, 2009-2019 is a professional and in-depth ... Hydrochloride industry. The report firstly reviews the ... classification, application and manufacturing technology. The report ... of Oxybutynin Hydrochloride listing their product specification, ...
Breaking Medicine Technology:In Era of Competing Needs, Market Research Groups Under Pressure to Utilize Automation and External Staffing 2PCMA: New OIG Report Cites Drug Manufacturer "Copay Coupon" Use in Medicare Part D 2Oxybutynin Hydrochloride Industry 2014-2019 Chinese Forecasts & Analysis 2Oxybutynin Hydrochloride Industry 2014-2019 Chinese Forecasts & Analysis 3Oxybutynin Hydrochloride Industry 2014-2019 Chinese Forecasts & Analysis 4Oxybutynin Hydrochloride Industry 2014-2019 Chinese Forecasts & Analysis 5
... is a family of solutions that ... individuals inside hospitals, healthcare facilities, or ... The target tracking areas are networked ... of radio frequency identification (RFID) readers ...
Assetrac allows identification, location, and protection of your assets....
... The RoamAlert Integrity system builds ... ECO. All door controllers in the ... computer running a standard Windows® operating ... the use of a personal computer, ...
... uses RFID to gather patient ... departments such as surgical and ... updates of patient location to ... care events have occurred and ...
Medicine Products: