Navigation Links
New Blood Thinner Linked to Higher Heart Attack Risk
Date:1/10/2012

r of the Vascular Neurology Fellowship Training Program at the Cleveland Clinic.

The report was published in the Jan. 9 online edition of the Archives of Internal Medicine.

In the large study that led to the approval of Pradaxa, there was a suggestion that Pradaxa might be associated with an increased risk of heart attacks, Uchino explained.

However, the drug's benefit for patients with atrial fibrillation outweighs the risk, he said.

"The increase of [heart attack] risk associated with dabigatran is small, and the benefit in prevention of stroke among persons with atrial fibrillation is greater," Uchino said.

Why Pradaxa is associated with an increased heart attack risk isn't clear, they say. It's possible Pradaxa doesn't increase heart attack risk directly, but it may not be as effective as warfarin and aspirin in preventing heart attacks, he added.

Dr. John Smith, senior vice president for clinical development and medical affairs at Boehringer Ingelheim, the makers of Pradaxa, said that "we don't agree with the conclusion and the method used for this meta-analysis. Based on all the data, we conclude that heart attack is not an adverse consequence of Pradaxa treatment."

Another expert said that the risk of heart attack does not outweigh the benefits of the drug, especially taking the risk of serious bleeding with warfarin into account.

"I would be cautious about this meta-analysis. It doesn't convince me," Dr. William O'Neill, a professor of cardiology and executive dean for clinical affairs at the University of Miami School of Medicine, said. "I am unimpressed by the data."

Warfarin, O'Neill added, "is a pretty lousy drug."

Although he estimated about one in 10 patients can't tolerate Pradaxa because of severe gastrointestinal side effects, "you don't have to monitor it the way you have to with warfarin. It's a big improvement over warfarin."

Dr. Jeremy Jacobs, a lecturer in geriatric medic
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Inflammatory Bowel Ups Risk for Blood Clots
2. Bowel disease link to blood clots
3. Local Blood Supply Impacted by Wednesdays Severe Snow Storm
4. PERSONALABS Offers Discounted Healthy Heart Online Blood Tests in February
5. China Cord Blood Corporation Warrant Registration Statement Declared Effective by SEC
6. NIH grants to Childrens Hospital will advance novel stem cell treatments for blood disorders
7. Bilberry Seems to Act Against Blood Sugar
8. Johns Hopkins scientists develop personalized blood tests for cancer using whole genome sequencing
9. UCR researcher identifies mechanism malaria parasite uses to spread in red blood cells
10. NHLBI, CDC launch surveillance and research program for inherited blood diseases
11. IOM report declares high blood pressure a neglected disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/29/2014)... of America (GSA) the nation,s largest interdisciplinary ... chosen Corinna E. Lckenhoff, PhD, of Cornell University as ... B. Baltes Foundation Award in Behavioral and Social Gerontology. ... career contributions in behavioral and social gerontology. Individuals who ... are eligible. The award is given by GSA in ...
(Date:7/29/2014)... 2014 The report “Filling Equipment ... (Rotary, Volumetric, Aseptic, Net Weight), Process (Manual, Semi-Automatic, ... Global Trend & Forecast to 2019”, defines the ... beverage, pharmaceutical, and cosmetic segments with analyses and ... these segments, in terms of value. It also ...
(Date:7/29/2014)... July 29, 2014 - What if ... source? That’s the big public health question being addressed ... risk program developed by Principled Strategies . SafeUseNow ... be part of The Hive at the ... The Hive is a community of exceptional startups and ...
(Date:7/29/2014)... -- With the increasing use of electronic medical ... growing demand for a computerized version of the ... States. In a new study, researchers from the ... Institute report that substantial work lies ahead to ... guidelines into computerized prompts for physicians, but the ...
(Date:7/29/2014)... Reseda, Calif (PRWEB) July 29, 2014 ... , The Discovery House recently participated in a community ... Valley. The group of volunteers partnered with the San ... to individuals in need. , The San Fernando Valley ... individuals and families. The mission's Family Emergency Shelter provides ...
Breaking Medicine News(10 mins):Health News:Löckenhoff earns GSA's 2014 Baltes Foundation Award 2Health News:Filling Equipment Market worth $8 Billion by 2019 - Report by MarketsandMarkets 2Health News:Filling Equipment Market worth $8 Billion by 2019 - Report by MarketsandMarkets 3Health News:Filling Equipment Market worth $8 Billion by 2019 - Report by MarketsandMarkets 4Health News:SafeUseNow Selected to Showcase at TEDMED Hive 2014 2Health News:SafeUseNow Selected to Showcase at TEDMED Hive 2014 3Health News:Study: Pediatric preventive care guidelines need retooling for computerized format 2Health News:Study: Pediatric preventive care guidelines need retooling for computerized format 3Health News:The Discovery House Employees Volunteer at Local Rescue Mission 2Health News:The Discovery House Employees Volunteer at Local Rescue Mission 3
... News) -- It seems that Americans really can be in ... visited five car shows in Arizona and conducted interviews with ... found that those with an especially strong attachment used pet ... In addition, some people used this emotional connection to ...
... of Medicine in St. Louis have learned why changes in ... the parasite Toxoplasma gondii . The answer has likely ... Toxoplasma and many other parasites. In a ... show that the ROP18 protein disables host cell proteins that ...
... Dec. 28 (HealthDay News) -- Preteens with conduct disorders are much ... they are teens, finds a new Canadian study. It followed ... 13 at the start of the study. Those who stole, ... likely to sell illicit drugs, nine times more likely to join ...
... Reporter , TUESDAY, Dec. 28 (HealthDay News) -- Sheri Foote ... have. Foote, 43 and a Denver resident, was first ... about age 21. "I knew I had a family history ... good thing to do," Foote recalled. Her cholesterol "was ...
... PAUL, Minn. Epilepsy, a common and serious neurologic disorder that ... and funding for research it deserves, according to an editorial ... issue of Neurology, the medical journal of the ... surveillance, or ongoing collection of data on newly diagnosed epilepsy, ...
... [Brown University] A novel potential therapy based on a ... in mice who have the same genetic mutation as boys ... a paper published online Dec. 27 in the Proceedings ... Dystrophy is a fatal genetic mutation in about one of ...
Cached Medicine News:Health News:Love of Possessions Can Run Deep, Study Shows 2Health News:Protein helps parasite survive in host cells 2Health News:Woman Struggles to Control Cholesterol 2Health News:Researchers: Pay more attention to epilepsy 2Health News:Human protein improves muscle function of muscular dystrophy mice 2
(Date:7/29/2014)... , July 29, 2014  Neurocrine Biosciences, Inc. ... Company will report its second quarter 2014 financial results ... 2014.  Neurocrine will then host a live conference call ... a Company update Thursday morning, August 7, 2014 at ... Participants can access the live conference call by ...
(Date:7/29/2014)... -- Sysmex America, Inc., a global leader in medical diagnostic ... exhibit booth during the American Association for Clinical ... in Chicago , July 27 through ... excited to exhibit at AACC this year, because it,s ... continue the dialogue on how to best meet the ...
(Date:7/29/2014)... , July 29, 2014 Apex Medical Corporation ... and Pressure Area Care sectors, announces that it is appealing ... in Germany that found ... Apex notes that it has initiated invalidity challenges against various ... efforts in counterattacking against trivial and junk patents. ...
Breaking Medicine Technology:Neurocrine Biosciences Announces Conference Call And Webcast To Report Second Quarter 2014 Financial Results 2New Product Offerings Highlight Sysmex's Presence at 2014 AACC in Chicago 2New Product Offerings Highlight Sysmex's Presence at 2014 AACC in Chicago 3Apex Continues Fighting Against Patents to Free Up Competition 2
... CPhI Worldwide and connected events - the global pharma ingredients and ... - 15 October for its 20th staging. , The co-located ... technology events are joined for 2009 under the Where Pharma ... The new platform markedly reflects the notable convergence of the pharma ...
... (Nasdaq: DYNT ) today announced the appointment of Douglas ... research and development, replacing Ronald Hatch, who has retired. , ... said Kelvyn Cullimore Jr., chairman and president of Dynatronics. "His ... operation as well as our research and development efforts here ...
Cached Medicine Technology:CPhI 2009: Madrid Launch for BioPh Marks Pharma and Biotech Convergence 2CPhI 2009: Madrid Launch for BioPh Marks Pharma and Biotech Convergence 3Dynatronics Appoints Douglas Sampson as Vice President of Production and Research & Development 2
... Chalam 15° Prism are designed ... are recommended for tractional retinal ... Rhegmatogenus retinal detachment. They can ... and other midperipheral laser applications. ...
... The High-Mag 1.5x ... internal limiting membrane peeling ... optic nerve neurotomy, sheathotomy ... traditional macular edema and ...
... visualization of virtually the entire retina including ... of the lens on the eye. It ... giant retinal tears, diagnosing and treating anterior ... retina in a vitreous cavity filled with ...
... higher magnification and increased stereopsis, ... suited for detailed visualization to ... Retinal is ideal for vitrectomy ... peeling in proliferative vitreoretinopathy extending ...
Medicine Products: