Navigation Links
New Benefits From Old Heart Measures
Date:4/14/2008

Statins lower blood pressure, DASH diet cuts cardiovascular risk, studies find

MONDAY, April 14 (HealthDay News) -- Two new studies describe additional benefits of widely used measures aimed at preventing cardiovascular disease: Cholesterol-lowering statins also reduce blood pressure, and the DASH diet for blood pressure control lowers the incidence of heart disease and stroke in middle-aged women.

The statin study wasn't intended to measure the effect of the drugs on blood pressure, said Dr. Beatrice Golomb, an associate professor of medicine at the University of California, San Diego. It was a classic double-blind, controlled trial with some of the 973 participants taking either simvastatin (Zocor) or pravastatin (Pravachol), and others taking a placebo. Neither doctors nor the participants knew who was taking what.

"But we got enough titillating information that we asked for permission to break the blind, and we looked at blood pressure before any other endpoint," Golomb said.

The blood pressure benefit was there, with systolic pressure (the top number) lower by an average of 2.2 milligrams of mercury for those taking a statin, and diastolic pressure (the bottom number) 2.4 milligrams lower. The reductions were about the same for both statins.

It's not a big drop, Golomb said, but "there are lots of studies showing that on a population basis, a few millimeters of reduction has a big effect on cardiac endpoints."

Golomb said she wouldn't put anyone on a statin expressly for blood pressure reduction, but "some people might be spared the need for a blood pressure medication when they are put on a statin for cholesterol reduction," she said.

The results, published in the April 14 issue of Archives of Internal Medicine, help to explain why treatment with statins has been associated with a reduction in the risk of stroke that couldn't be attributed to the drugs' effect on blood cholesterol, she said.

The DASH -- Dietary Approaches to Stop Hypertension -- study, reported in the same issue of Archives of Internal Medicine, is the first to look at the diet's effect on the incidence of heart disease and stroke, said study author Teresa T. Fung, an associate professor of nutrition at the Simmons College School for Health Studies in Boston.

"Previously, the benefits that were reported were for hypertension [high blood pressure]," Fung said. "No previous study looked at cardiovascular endpoints such as heart disease and stroke."

The study reported on 88,517 female nurses aged 34 to 59 who started with no evidence of cardiovascular disease or diabetes in 1980. In the 24 years that followed, the one-fifth of women in the group whose diets were most similar to that recommended in DASH -- low in animal protein, moderate in low-fat dairy products and high in plant proteins -- were 24 percent less likely to develop coronary heart disease and 18 percent less likely to have a stroke than the one-fifth of women with the lowest DASH scores.

While the study was not the kind of carefully controlled trial that gets the highest regard in research, it carries a message, Fung said. "This report actually shows that those people whose diet resembles the DASH diet reduce the risk of actual cardiovascular disease," she said.

More information

You can learn more about statins from the American Heart Association, and the DASH diet from the U.S. Heart, Lung, and Blood Institute.



SOURCES: Beatrice Golomb, M.D., Ph.D, associate professor, medicine, University of California, San Diego; Teresa T. Fung, Ph.D, associate professor, nutrition, Simmons College, Boston; April 14, 2008, Archives of Internal Medicine


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Practice-based intervention has sustained benefits for children and families
2. Manic phase of bipolar disorder benefits from breast cancer medication
3. Scientists highlight benefits of genetic research in sport, but warn of ethical concerns
4. Smaller breast reduction surgeries provide health benefits and should be reimbursed
5. Cholesterol byproduct blocks heart health benefits of estrogen
6. A Place for Mom, Nations Largest Senior Care Referral Service, Fills a Gap in Employee Benefits
7. New Herbal Water Creating Taste Sensation: Ayalas Herbal Water Has No Calories, No Preservatives and No Artificial Additives. Just All the Natural Benefits of Herbs!
8. Hazards of using crib bumper pads outweigh their benefits
9. Dominium Benefits Experiencing Dynamic Growth
10. The Integrated Benefits Institute Offers Largest Benchmarking Database in U.S. Spanning Disability and Workers Compensation Programs
11. Physiotherapy has short-term benefits for patients after knee surgery
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Benefits From Old Heart Measures
(Date:6/26/2016)... , ... June 26, 2016 , ... ... once they have been diagnosed with endometriosis. These women need a treatment plan ... require a comprehensive approach that can help for preservation of fertility and ultimately ...
(Date:6/25/2016)... ... 2016 , ... First Choice Emergency Room , the largest network of ... Medical Director of its new Mesquite-Samuell Farm facility. , “We are pleased to ... said Dr. James M. Muzzarelli, Executive Medical Director of First Choice Emergency Room. ...
(Date:6/24/2016)... Los Angeles, CA (PRWEB) , ... June 24, 2016 , ... ... plastic surgery procedures that most people are unfamiliar with. The article goes on to ... known procedures, but also many of these less common operations such as calf and ...
(Date:6/24/2016)... MIAMI, Fla. (PRWEB) , ... June 24, 2016 , ... ... Florida Trend magazine’s 2016 Legal Elite. The attorneys chosen by their peers for this ... of Florida. , Seven Greenberg Traurig Shareholders received special honors as members of this ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... the Clinical Decision Making in Emergency Medicine conference in Ponte Vedra Beach, FL. ... articles published in Emergency Medicine Practice and Pediatric Emergency Medicine Practice. ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 Research and ... Global Market - Forecast to 2022" report to their ... treatment method for the patients with kidney failure, it replaces ... fluid from the patient,s blood and thus the treatment helps ... and chloride in balance. Increasing number of ...
(Date:6/23/2016)... , June 23, 2016 Roche (SIX: ... 510(k) clearance for its Elecsys BRAHMS PCT (procalcitonin) assay ... sepsis or septic shock. With this clearance, Roche is ... a fully integrated solution for sepsis risk assessment and ... with bacterial infection and PCT levels in blood can ...
(Date:6/23/2016)... -- Bracket , a leading clinical trial technology and ... platform, Bracket eCOA (SM) 6.0, at the 52 nd ... 2016 in Philadelphia , Pennsylvania.  A demonstration ... of its kind to fully integrate with RTSM, will be ... is a flexible platform for electronic clinical outcomes assessments that ...
Breaking Medicine Technology: