Navigation Links
New Batch of Lupus Genes Discovered
Date:1/21/2008

Rose explained.

The discovery that many genes are involved "means we may be one step closer to better therapies in the short run -- several years as opposed to 10 years. If we can figure out what these genes are responsible for and we can alter that, we may have a major impact on the disease," said Dr. Susan Manzi, co-director of the Lupus Center for Excellence at the University of Pittsburgh and a co-author on one of the studies.

"A better understanding of why you have this disease and what's gone wrong [creates] a potential to target better therapies," she added. A greater definition of which genes are implicated in symptoms of lupus involving the brain or kidneys, for example, would allow for more accurate screening and monitoring of people at risk for lupus, she explained.

"The holy grail is for you to have a set of genes that when they are together in the right combination incur an extremely high risk" so that people at risk can be identified and vaccinated to prevent the disease, Manzi added.

Some of the papers are the result of the recent availability of new microchip technology that allows genome-wide scans, according to Dr. Carl Langefeld, co-director of the International Consortium for Systemic Lupus Erythematosus Genetics (SLEGEN), which produced the discoveries reported in Nature Genetics.

Referring to some of the studies' overlap in results, Langefeld added, "The identification of the same genetic markers in different samples further strengthens our confidence in these findings."

A fifth study done by the Scripps Institute, which appeared in the Jan. 18 issue of Immunity, took an entirely different approach, focusing instead on a genetic mutation that reduces one's risk of developing lupus, Rose added.

Lupus can affect the skin, joints, lungs, blood and other organs, and lead to cardiovascular, kidney and arthritic problems, according to the Lupus Foundation of
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. NEJM editorial on significance and limitations of new lupus gene expression research
2. Scientists identify genes linked to lupus in women
3. Lupus in women: New genetic risk factors identified
4. Scripps research scientists find new genetic mutation that halts the development of lupus
5. Lupus Foundation of America Urges Social Security Administration Not to Adopt Proposed 5-Day Rule
6. 2007: A Watershed Year for Lupus Research and Education
7. Lupus Foundation of America Offers Webchat for Parents of Teens with Lupus on December 12 at 3:00 p.m. Eastern Time
8. S.L.E. Lupus Foundation Gala Raises Record $3.2 Million for Lupus
9. Researchers investigate ways to detect lupus-associated kidney disease
10. Research suggests targeted treatment strategies for lupus
11. Mayo Clinic shows therapy effective for reducing lupus flares
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Batch of Lupus Genes Discovered
(Date:6/29/2015)... ... June 29, 2015 , ... With Urgent Care Medicine now serving a vital ... Board of Urgent Care Medicine and the Medical Society of Delaware to provide its ... physicians and health care professionals. , According to Matthew Bader, Exam Master CEO and ...
(Date:6/29/2015)... CA (PRWEB) , ... June 29, 2015 , ... ... designed to lift and tighten sagging skin. Ulthera is a special treatment that offers ... it uses ultrasound technology to gently stimulate collagen production. Ulthera is highly targeted and ...
(Date:6/29/2015)... ... June 29, 2015 , ... ... Conference shows that fewer than 10 percent of U.S. state and local governments ... have set an implementation deadline for NG9-1-1. , “Mobile phones have surpassed ...
(Date:6/29/2015)... MI (PRWEB) , ... June 29, 2015 , ... Celebrities ... perfect ten and have flawless skin all summer long and beyond. People don’t ... simple steps to slow the aging process, maintain an even skin tone, avoid breakouts, ...
(Date:6/29/2015)... , ... June 29, 2015 , ... ... personality type and behavior, is a popular focus for corporate training seminars. As ... streamline hiring practices, improve training, foster teamwork, and increase productivity. , With ...
Breaking Medicine News(10 mins):Health News:Exam Master Partners to Provide New Urgent Care Continuing Medical Education Resource 2Health News:Exam Master Partners to Provide New Urgent Care Continuing Medical Education Resource 3Health News:Dermatologist, Dr. Peyman Ghasri, is Now Offering Non-Invasive Skin Tightening Procedures 2Health News:Dermatologist, Dr. Peyman Ghasri, is Now Offering Non-Invasive Skin Tightening Procedures 3Health News:State and Local Governments Are Slow to Adopt Next Generation 9-1-1 Systems, According to New Research from General Dynamics Information Technology 2Health News:State and Local Governments Are Slow to Adopt Next Generation 9-1-1 Systems, According to New Research from General Dynamics Information Technology 3Health News:State and Local Governments Are Slow to Adopt Next Generation 9-1-1 Systems, According to New Research from General Dynamics Information Technology 4Health News:Skin Guru Shares Celebrity FACE Secrets For Summer-Proofing The Skin 2Health News:Skin Guru Shares Celebrity FACE Secrets For Summer-Proofing The Skin 3Health News:As Demand for DISC Trainers Rises, PeopleKeys Offers Support with “THE DISC FACTOR—Train the Trainer” Webinar 2
... HealthDay Reporter , MONDAY, Dec. 27 (HealthDay News) -- Marilyn ... both eyes. "They saw them back then and said, ,Someday ... and living in Oklahoma City, recalled. That time came this ... -- the right eye on May 27 and the left eye ...
... the amygdala, a small almond shaped structure deep within the ... life among humans. The finding was published this week ... to previous findings in other primate species, which compared the ... "We know that primates who live in larger social groups ...
... Reporter , FRIDAY, Dec. 24 (HealthDay News) -- For years ... of lupus, a chronic autoimmune condition that can wrack the ... now are preparing for a potential major leap forward. ... treatment for the disease was endorsed in mid-November by an ...
... FRIDAY, Dec. 24 (HealthDay News) -- It,s one of the ironies ... of your favorites of the whole year -- can leave you ... abdominal pain and even symptoms such as fatigue and sadness. Conditions ... challenges. "We all love holiday food, but we can,t ...
... Reporter , FRIDAY, Dec. 24 (HealthDay News) -- Wendy Rodgers began ... would wake up very stiff and achy," said Rodgers, now 37 ... get going in the morning." Then, after feeling this way ... morning and it was like I was paralyzed," she recalled. "I ...
... Dec. 23 (HealthDay News) -- Driving is a bad idea for ... recovering from an injury or surgery to their right foot, a ... much longer to brake when a driver is wearing an ankle ... emergency braking time in volunteers using a brake adapted for use ...
Cached Medicine News:Health News:Have Cataracts? Get Surgery, Woman Urges 2Health News:Structure deep within the brain may contribute to a rich, varied social life 2Health News:Lupus Treatment May Soon Take Leap Forward 2Health News:Lupus Treatment May Soon Take Leap Forward 3Health News:Surviving the Holiday Buffet 2Health News:For California Woman, Lupus Is Life 2Health News:Driving a Bad Idea for People Wearing a Cast, Brace: Experts 2
(Date:6/29/2015)... ZIONA, Israel , June 29, ... BVXV, TASE: BVXV) today announced positive preliminary results from ... candidate for a universal influenza vaccine. In this trial, ... of 50 to 65, followed by an administration of ... later. M-001 was found to be safe and well ...
(Date:6/29/2015)... Calif. , June 29, 2015  Isis Pharmaceuticals, ... has been added to the Russell 1000 Index, effective ... performance of the large-cap segment of the U.S. equity ... Index and includes approximately 1000 of the largest securities ... current index membership. "We are pleased to ...
(Date:6/29/2015)... Calif. , June 29, 2015  Arbor ... medical workstation lineup. The high-powered, multi-functional M2150 ... generation Intel® Haswell Core i5-4402E 1.6 ... provide significant data processing and computing performance. Integrated ... making the unit well suited for graphics-intense applications ...
Breaking Medicine Technology:BiondVax Presents BVX-006 Preliminary Phase II Results: the Universal Flu Vaccine at Higher Doses is Safe and Improves Immunogenicity in Older Adults 2BiondVax Presents BVX-006 Preliminary Phase II Results: the Universal Flu Vaccine at Higher Doses is Safe and Improves Immunogenicity in Older Adults 3ISIS Pharmaceuticals Promoted to the Large-Cap Russell 1000 Index 2ISIS Pharmaceuticals Promoted to the Large-Cap Russell 1000 Index 3Arbor Solution Introduces Multi-Function Medical Workstation with Large 21.5" True Flat Touch Screen 2Arbor Solution Introduces Multi-Function Medical Workstation with Large 21.5" True Flat Touch Screen 3
... , CHEYENNE, Wyo., Aug. 24 The ... of its Pay-for-Participation (P4P) program, a component of its innovative ... collaboration between the practitioner community and the Wyoming EqualityCare (EC) ... Wyoming Medicaid members. , , (Logo: ...
... Curemark Founder and CEO Dr. Joan Fallon delivered the ... Conference at Harvard Medical School on July 14th. , ... conclave is particularly significant, since epigenetics is the study of ... in the DNA sequence. Presenters at the session showcased many ...
Cached Medicine Technology:Wyoming Department of Health's Pay-for-Participation Program Reports Positive Clinical Outcomes 2Wyoming Department of Health's Pay-for-Participation Program Reports Positive Clinical Outcomes 3Curemark CEO Presents at Epigenomics Conference 2
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: