Navigation Links
New Anti-Clotting Treatment Urged for Cancer Patients
Date:2/13/2009

Warfarin failed to reduce catheter-related clots, study finds,,

FRIDAY, Feb. 13 (HealthDay News) -- The blood thinner warfarin does not reduce catheter-related blood clots in cancer patients, so new treatments are needed to prevent this complication, says a U.K. study.

About 50 percent of cancer patients develop venous thromboembolism, which can be caused by a number of factors, including the use of central venous catheters to deliver infusional chemotherapy, according to background information in the study. The use of warfarin with the catheters to prevent clotting is controversial because there's no clear evidence that it's effective.

The study included 1,590 cancer patients at 68 centers who were receiving chemotherapy through central venous catheters. The patients were randomly selected to receive either no warfarin, a fixed dose of 1 milligram of warfarin a day or dose-adjusted warfarin daily.

Overall, rates of catheter-related blood clots were the same (6 percent) whether people were or were not given warfarin. Those who received dose-adjusted warfarin did have fewer blood clots than those given the fixed dose (3 percent vs. 7 percent), but there were more occurrences of major bleeding in the dose-adjusted group (16 vs. 7).

The study was published in this week's edition of The Lancet.

"The rate of symptomatic catheter-related thromboses reported in clinical trials has fallen substantially over the past decade," wrote Annie Young and colleagues from the Institute for Cancer Studies at the University of Birmingham. "The improvements in catheter technology, placement and aftercare are contributing to this reduction. When any benefit of thromboprophylaxis (treatment to prevent blood clots) was balanced against the risk of major bleeding, the combined outcome showed no advantage with the use of any dose of warfarin."

"These findings only add to the assertion that the time has come to move on from warfarin for thromboprophylaxis in patients with cancer," they wrote. "We should consider new treatments."

Dr. Paolo Prandoni, of the University of Padua in Italy, wrote in an accompanying editorial that though there's no evidence that warfarin helps prevent catheter-related blood clots in cancer patients, doctors should make an effort to identify people at highest risk of clotting because they might benefit most from anti-clotting treatment.

More information

The American Society of Clinical Oncology has more about preventing and treating blood clots.



-- Robert Preidt



SOURCE: The Lancet, news release, Feb. 12, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Anti-Clotting Drug as Good as Aspirin at Stopping Second Stroke
2. Anti-Clotting Drug Helps Infants With Heart Ills
3. Anti-Clotting Drug Trial Shortened by Bleeding Problems
4. Researchers identify molecules with interesting anti-clotting properties
5. New Anti-Clotting Drug Shows Promise in Heart Patients
6. Possible safer target for anti-clotting drugs found
7. New Anxiety and Mood Disorders Intensive Treatment Program in Downtown Chicago
8. Free Community Seminar to Review Treatment Options for Enlarged Prostate
9. TV News Coverage Reports on InnerCools CoolBlue System Treatment of Cardiac Shock Patient Following Childbirth at Rush Hospital, Chicago
10. DOR BioPharma Announces Potential $30 Million North American Partnership Agreement with Sigma-Tau Pharmaceuticals for orBec(R) in the Treatment of Graft-versus-Host Disease
11. Electronic Health Record Advances Patient-Centered Cancer Care at Cancer Treatment Centers of America
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Anti-Clotting Treatment Urged for Cancer Patients
(Date:6/24/2016)... ... June 24, 2016 , ... Puradigm® ... Group (TGIG), has initiated cultivation and processing operations at its production facility, and ... Nevada. , Puradigm is the manufacturer of a complete system of proactive air ...
(Date:6/24/2016)... ... 2016 , ... Advanced Plastic Surgery Institute ( http://www.advancedplasticsurgeryinstitute.com ), ... official Medspa Sponsor. Dr. Josh Olson, a board-certified plastic surgeon, owns the practice, ... says the decision to support the pageant in an official capacity is a ...
(Date:6/24/2016)... ... June 24, 2016 , ... SpiritQuest Sedona Retreats, located in ... Sedona, surrounded by famous vortex sites: Cathedral Rock, Airport Mesa, and Boynton Canyon. The ... the Lodge at Sedona as well as the Sedona Rouge, both popular accommodations for ...
(Date:6/23/2016)... (PRWEB) , ... June 23, 2016 , ... The Mechille ... business clients throughout Jasper County and the surrounding region, is initiating a charity drive ... drive will raise funds earmarked for a scholarship fund that will be presented to ...
(Date:6/23/2016)... NJ (PRWEB) , ... June 23, 2016 , ... ... today’s Appellate Court ruling a victory for consumers seeking relief from the crushing ... Docket No. A2913-15T2 & A2929-15T2. , In their ruling ( http://www.judiciary.state.nj.us/opinions/a2913-15a2929-15.pdf ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... FRANCISCO, Calif. , June 24, 2016 /PRNewswire/ ... ), a biopharmaceutical company developing novel therapeutics for ... unmet needs, today announced the closing of its ... of common stock, at the public offering price ... in the offering were offered by GBT. GBT ...
(Date:6/24/2016)... DUBLIN , June 24, 2016 ... addition of the "Structural Electronics 2015-2025: Applications, ... In-Mold Electronics, Smart ... Integrated Photovoltaics Structural electronics involves ... as load-bearing, protective structures, replacing dumb structures such ...
(Date:6/24/2016)... SAN CLEMENTE, Calif. , June 24, 2016  American Respiratory ... testing company, is now able to perform sophisticated lung assessments in ... Medical Technologies , Inc. Patients are no longer ... to ndd,s EasyOne PRO ® , ARL patients like Jeanne R. ... testing done in the comfort of her own home. ...
Breaking Medicine Technology: