Navigation Links
New Alzheimer's findings: High stress and genetic risk factor lead to increased memory decline
Date:8/27/2007

Philadelphia, PA, August 27, 2007 High stress levels may contribute to memory loss among people at risk for developing Alzheimers disease. The 4 variant of the apolipoprotein E (APOE) gene contributes to the risk for memory loss related to Alzheimers disease. Similarly, high circulating levels of cortisol, associated with high stress levels, also impairs memory. However, the interactive effects of this risk genotype and chronic stress are not well understood, so a new study being published in the September 1st issue of Biological Psychiatry was designed to explore this relationship.

In their study, Peavy and colleagues performed genotyping and measured the chronic stress level in 91 older, healthy subjects (mean age was 78.8 years). Those low on stress or without the APOE- 4 risk factor performed better on memory measures than those with high stress or those positive for APOE-4, respectively. Those individuals experiencing high stress and who were positive for APOE- 4 showed the greatest memory impairment.

One of the authors, Guerry M Peavy, Ph.D., comments, "Perhaps the most interesting result of the study was the interaction we found between genetic status and the experience of high stress events. That is, for some aspects of memory, highly stressful experiences had a detrimental effect only on those individuals who carried the APOE-4 allele.

John H. Krystal, M.D., Editor of Biological Psychiatry and affiliated with both Yale University School of Medicine and the VA Connecticut Healthcare System, adds:

This is a very exciting time in Alzheimers disease (AD) researchThe findings of Peavy et al. suggest that environmental factors, like chronic stress, may interact with an AD risk genotype, APOE-4, to promote age-related memory impairment. These data raise the possibility that psycho-social interventions and psychotherapeutic medications might enhance the effectiveness of medication treatment strategies aimed at prese
'/>"/>

Contact: Jayne M. Dawkins
ja.dawkins@elsevier.com
215-239-3674
Elsevier
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Testing genes for disease does not cause harm to children of people with Alzheimers
2. Age-Dependent Alterations Not Specific For Alzheimers Disease
3. Killing two birds (cholesterol and Alzheimers disease) with the same stone
4. Cancer Causing Protein May Heal Alzheimers
5. Exposure To High Aluminum Levels In Tap Water Lead To Rare Form Of Alzheimers
6. Sugar variant may make a world of difference to Alzheimers disease
7. Alzheimers Disease Enzyme may Interfere With Brain Function
8. Emotional Stress Could Be a Factor in Causing Alzheimers: Study
9. Alzheimers Incidence is Set to Quadruple by 2050
10. GAB2-A New Alzheimers Gene Identified
11. Reduced Oxygen to the Brain Increases Alzheimers Risk in Stroke Victims
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/22/2014)... FL (PRWEB) December 22, 2014 Coral Gables ... removal service , Lice Troopers, with its new clinic location ... southern Florida, takes the hassle out of dealing with this ... in one of their two salon clinic locations in South ... other location. , The decision to expand developed naturally out ...
(Date:12/22/2014)... December 22, 2014 International ... Ebola virus epidemic are receiving further support ... agencies, nongovernmental organizations (NGOs) and other charitable ... healthcare workers, emergency responders, patients and others ... as the CmTP MediDefense system , ...
(Date:12/22/2014)... Colorado (PRWEB) December 22, 2014 Super ... Black Friday this year as the busiest day in ... other retailers, The Grass Station had a steady pre-Christmas ... holiday gifts, this past Saturday. , “I definitely intend ... 33-year-old Robert, a Denver resident who was enjoying The ...
(Date:12/22/2014)... 22, 2014 The MedTech industry is gearing ... wholly owned subsidiary of PartnerTech AB of Sweden, is prepared ... achieved additional ISO Certification. , All signs point to growth ... the likelihood of a repeal of the excise tax originally ... industry is anticipating annual growth of 9.3% and PartnerTech Inc. ...
(Date:12/22/2014)... December 22, 2014 Luxury Linen purveyor ... Partners of Dallas to provide logistics and support for ... Peacock Alley has a long history of giving back to ... sponsors of this year's Toy Drive were Whataburger® and 99.5 ... back than the holidays. Providing gifts to children who would ...
Breaking Medicine News(10 mins):Health News:Professional In-Home All-Natural Lice Removal Service Expands to Coral Gables and surrounding areas. 2Health News:Novel Biostatic Antimicrobial Technology From Clearstream-mPact Technology Partnership (CmTP) Offers Effective Protection Against Transmission of Ebola Virus 2Health News:Novel Biostatic Antimicrobial Technology From Clearstream-mPact Technology Partnership (CmTP) Offers Effective Protection Against Transmission of Ebola Virus 3Health News:Novel Biostatic Antimicrobial Technology From Clearstream-mPact Technology Partnership (CmTP) Offers Effective Protection Against Transmission of Ebola Virus 4Health News:Novel Biostatic Antimicrobial Technology From Clearstream-mPact Technology Partnership (CmTP) Offers Effective Protection Against Transmission of Ebola Virus 5Health News:Customers at Colorado’s Grass Station Say They’re Enjoying the Experience of Legally Purchasing Marijuana this Year to Give as Christmas Presents to Friends and Family 2Health News:PartnerTech Inc. Poised for Growth in MedTech 2Health News:Peacock Alley and Community Partners of Dallas Fulfill an Estimated 12,000 Holiday Wishes for Deserving Children 2
... 2010 - The 1994 genocide in Rwanda resulted in the ... course of about 100 days. Although the exact death ... of the country,s entire population was murdered. There can ... survivors developed posttraumatic stress disorder, or PTSD, an anxiety disorder ...
... rats, treatment boosts blood vessel and nerve cell growth, researchers ... the results of preliminary research in rats, researchers say that ... could help people recover brain function after a stroke. , ... induced ischemic strokes showed signs of blood vessel growth and ...
... ... on Outsourcing , ... Westborough, MA (PRWEB) February 25, 2010 -- Advans, a solution provider and IT ... popularity of domestic outsourcing. According to the Advans’ IT Outsourcing Survey, 75 percent of ...
... ... Promises New Insight , ... Rosemont, IL (Vocus) February 25, 2010 -- Dr. Robert C. Bray of the ... Society for Sports Medicine’s (AOSSM) $250,000 Ligament and Tendon Repair and Regeneration Grant ...
... ... and overwhelmed state agencies are possible causes for the increase in health care inquiries. ... Cleveland, OH ... health insurance quotes from HealthInsuranceSort. The need for individual health insurance from private ...
... Researchers from the Toronto Western Research Institute noted a ... in the U.S. versus the Canadian population. The authors ... a greater level of obesity and physical inactivity in ... published in the March issue of Arthritis Care ...
Cached Medicine News:Health News:Rwandan genocide survivors provide new insights into resilience and PTSD 2Health News:Vitamin B3 May Help Repair Brain After a Stroke 2Health News:Advans Survey Reveals that 75 Percent of Executives Prefer Domestic Outsourcing vs. Offshore 2Health News:$250,000 Grant Awarded for Groundbreaking Ligament and Tendon Repair Research 2Health News:HealthInsuranceSort.com Provides Record Number of Health Insurance Quotes in 2009 2Health News:Obesity and physical inactivity poses arthritis risk, especially for women 2
(Date:12/19/2014)... 18, 2014 Somewhere between dropping five pounds ... forgotten. But Audicus , a next-generation hearing aids ... new year. Hearing loss is the third ... though it is often unaddressed. Forty-eight million Americans have ... hearing aid, mainly due to price. Hearing aids traditionally ...
(Date:12/19/2014)... CITY, Calif., Dec. 18, 2014 Capnia, ... the development of medical diagnostics based on its ... gas flow, today announced financial results for the ... 2014. "Following the completion of our ... positioned to maximize the recently initiated CoSense® commercial ...
(Date:12/19/2014)... KANSAS CITY, Kan. , Dec. 18, 2014 ... PETX ), a biopharmaceutical company focused on ... for companion animals, today announced positive results from ... company,s innovative drug for treating pain in dogs ... demonstrated improvements in pain assessment scores that were ...
Breaking Medicine Technology:Audicus Will Help People Resolve to Hear Better in 2015 2Capnia Reports Third Quarter 2014 Financial Results 2Capnia Reports Third Quarter 2014 Financial Results 3Capnia Reports Third Quarter 2014 Financial Results 4Capnia Reports Third Quarter 2014 Financial Results 5Capnia Reports Third Quarter 2014 Financial Results 6Capnia Reports Third Quarter 2014 Financial Results 7Capnia Reports Third Quarter 2014 Financial Results 8Aratana Therapeutics Announces Positive Top-Line Results from AT-001 Pivotal Field Study in Client-Owned Dogs with Osteoarthritis 2Aratana Therapeutics Announces Positive Top-Line Results from AT-001 Pivotal Field Study in Client-Owned Dogs with Osteoarthritis 3Aratana Therapeutics Announces Positive Top-Line Results from AT-001 Pivotal Field Study in Client-Owned Dogs with Osteoarthritis 4Aratana Therapeutics Announces Positive Top-Line Results from AT-001 Pivotal Field Study in Client-Owned Dogs with Osteoarthritis 5
...  Neurocrine Biosciences, Inc. (Nasdaq: NBIX ) today ... 9,500,000 shares of its common stock at a price ... proceeds to Neurocrine from this offering, before deducting underwriting ... Neurocrine, are expected to be approximately $77 million. The ...
... of the Boy Scouts of America announced today that ... Merit Badge requirements through an event hosted by the ... Boy Scout participants will have the chance to interact ... guidance they can participate in activities geared toward badge ...
Cached Medicine Technology:Neurocrine Biosciences, Inc. Prices Public Offering of Common Stock 2Neurocrine Biosciences, Inc. Prices Public Offering of Common Stock 3Catalina Council Boy Scouts Partner With Sanofi US Tucson Research Center to Host First-Ever Chemistry Merit Badge Program 2Catalina Council Boy Scouts Partner With Sanofi US Tucson Research Center to Host First-Ever Chemistry Merit Badge Program 3
For the qualitative detection of cardiac troponin I (cTnl) in human whole blood and serum specimens...
For the qualitative detection of cardiac troponin I (cTnl) in human whole blood and serum specimens...
For the qualitative detection of antibodies to Treponema pallidum in human serum, plasma and whole blood specimens...
For the qualitative detection of antibodies to HIV-1 and HIV-2 in human serum, plasma and whole blood specimens...
Medicine Products: