Navigation Links
Neurons work like a chain of dominos to control action sequences
Date:10/24/2010

CAMBRIDGE, Mass. -- As anyone who as ever picked up a guitar or a tennis racket knows, precise timing is often an essential part of performing complex tasks. Now, by studying the brain circuits that control bird song, MIT researchers have identified a "chain reaction" of brain activity that appears to control the timing of song.

The song of the zebra finch is very stereotypic; each song lasts about 1 second, and consists of multiple syllables whose timing is almost precisely the same from one performance to the next. "It's a great model system for studying how the brain controls actions", says Michale Fee, senior author of the study and a member of the McGovern Institute for Brain Research.

The brain structures involved in bird song production have been identified, and Fee and colleagues had previously shown that the tempo of the song is controlled by a brain area known as HVC. During the 1-second song, individual neurons in HVC fire just one short burst of activity at a precise time point within the song. Different neurons fire at different times, so the activity of these neurons represents a 'time stamp' that causes the correct instructions to be sent to the vocal organs at each instant within the song.

But how does each HVC neuron know when to fire with such perfect timing? Several different ideas have been proposed, but one especially appealing idea is the "synfire chain" model, in which neurons fire in a chain reaction each one triggering the next in the sequence, like a cascade of falling dominos.

In a new study, which appears in the October 24 online issue of Nature, Fee and colleagues have now tested this idea using intracellular recordings, an approach that can record tiny voltage fluctuations in individual HVC neurons. In a technical tour-de-force, they developed a method in which these recordings could be made while the bird was freely moving around his cage and engage in natural behaviors such as si
'/>"/>

Contact: Jen Hirsch
jfhirsch@mit.edu
617-253-1682
Massachusetts Institute of Technology
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Neurons cast votes to guide decision-making
2. Neuralstem stem cells survive and differentiate into neurons in rats with stroke
3. With magnetic nanoparticles, scientists remotely control neurons and animal behavior
4. Blinking neurons give thoughts away
5. U of M study finds fast food chains have significantly decreased trans fats in cooking oils
6. “Global Supply Chain Visibility and Security; Business Necessity, Regulatory Imperative”
7. Eliminate Black Holes in Contract Manufacturing: Supply Chain Teams Seize Control of Production with the TraceLink Secure Business Cloud
8. Champlain Health Supply Services Selects GHX Connectivity, Software Solutions to Enhance Supply Chain Services for 11 Hospitals
9. Prominent New York City Real Estate Investor, Attorney and Atlanta Nursing Home Chains Pay $14 Million to Settle Whistleblower Kickback Case
10. Two Atlanta-Based Nursing Home Chains and Their Principals Pay $14 Million to Settle False Claims Act Case
11. Global Hospitals and Healthcare Suppliers Focus on Cutting Costs and Improving Quality at 2010 GHX Supply Chain Summit
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/30/2014)... Beach, Calif. (PRWEB) August 30, 2014 Insomnia ... Francis helps listeners understand how they unknowingly developed insomnia and ... have restful nights during. Tune in to the show ... The show airs live on August 30, and will ... more information on programming, go to DrCarolFrancisTalkRadio.com. , ...
(Date:8/30/2014)... 30, 2014 Hastings and Hastings, a ... located throughout Arizona is pleased to report having saved ... specific example among many cases where Hastings and Hastings ... to retain a greater portion of their settlement or ... providing a positive solution for Arizona car accident victims ...
(Date:8/30/2014)... "My niece developed a nighttime fever, and I ... fever might get worse," said an inventor from Montgomery, ... how she was doing, I developed this monitoring system." ... a child's temperature. The unit instantly alerts parents if ... medical care can be given, which is designed to ...
(Date:8/30/2014)... "I had a handicapped friend who could not walk along ... Wetumpka, Ala. "In order to help her be able to ... up with a way for her to use her crutches ... patent-pending Deezers to allow crutches to be used on uneven ... or canes at the beach. The device reduces the risk ...
(Date:8/30/2014)... WA (PRWEB) August 30, 2014 One of ... this era is the gluten-free diet. Originally meant for sufferers ... become a catchall for people who are looking to get ... However, not only is this kind of information erroneous, it ... health problems because of a drastic change in their ...
Breaking Medicine News(10 mins):Health News:Sleepless Nights, Exhausting Days, Mental Fog – Relief for Insomnia With Clinical Psychologist Dr. Carol Francis 2Health News:Hastings and Hastings Is Pleased To Report Having Saved A Client $67,100 On A Settlement Of $610,000 2Health News:“What is Gluten: Three Things You Need to Know Before Adopting a Gluten-Free Diet” Reveals What Readers Need to Know About the Benefits of a Strict Gluten Diet - Vinamy 2
... Unique off-label marketing case results in $425M ... government,s investigation,into Cephalon Inc.,s illegal marketing practices ... plea by the pharmaceutical company began,in January ... Ohio., The sales representative, Bruce Boise, ...
... Bear Bryant,Awards committee of the American Heart Association has ... has been named the,2009 winner of its, Lifetime Achievement ... Award at the Paul Bear,Bryant College Football Coaching Awards ... in Houston. The award recognizes excellence in,coaching on and ...
... pharmacy chain Walgreens has paid the United ... resolve allegations of falsely billing,the Medicaid program, ... submitted claims to Medicaid agencies in four ... both by Medicaid and by,private third-party insurance. ...
... More and more cancer patients are,looking for treatment ... of,life during difficult treatment regimens., ... at:, http://media.medialink.com/WebNR.aspx?story=35774 ) Philips Research is developing ... the effectiveness and reduce the side,effects of chemotherapy ...
... study also finds too many clinicians still using ... -- In children and teens, individual and group ... stress disorder (PTSD) and other trauma symptoms, say ... studies on the subject. , However, despite the ...
... it a “carrier of choice” for many in the medical device ... ... -- All medical devices share a critical need regardless of their ... the supply chain. For medical devices traveling to cross border ...
Cached Medicine News:Health News:Ohio Sales Rep's Information Launched Massive Government Investigation of Cephalon 2Health News:Ohio Sales Rep's Information Launched Massive Government Investigation of Cephalon 3Health News:Ohio Sales Rep's Information Launched Massive Government Investigation of Cephalon 4Health News:Barry Switzer to Receive Paul 'Bear' Bryant Lifetime Achievement Award 2Health News:Walgreens Pays U.S. $9.9 Million to Settle Medicaid Prescription Drug Allegations 2Health News:Cognitive Behavioral Therapy Best for Traumatized Youths 2Health News:Medical Device Producers Express Interest in Purolator USA's Express Service and Customer Service 2
(Date:8/29/2014)... -- Research and Markets has announced the ... & Pipeline Insight 2014" report to their offering. ... and eradicate the prevalence of cancer have achieved limited ... low specificity, safety and large number of side effects, ... solution. It has been discovered that peptides can be ...
(Date:8/29/2014)... Aug. 29, 2014 Does your doctor know what ... doctors have recommended marijuana to the over 112,000 currently registered ... the majority of the other roughly 20,300+ active physicians listed ... little about it – even though a poll in February ... say they have tried it. "With marijuana ...
(Date:8/29/2014)... Corporation , a neurodiagnostics medical device company based in ... Forcht Dagi , MD, DmedSc, MPH, MBA, FACS, FRCSEd  was ... " Teo Forcht Dagi is an experienced leader with ... said Remis Bistras , President and CEO of Vittamed. ... entrepreneurial expertise to our Board." Dr. Dagi is ...
Breaking Medicine Technology:Global Peptide Cancer Therapeutics Market & Pipeline Insight 2014 2Medical Rules Marijuana Sales in Colorado But Most Doctors Still in the Dark 2Medical Rules Marijuana Sales in Colorado But Most Doctors Still in the Dark 3Medical Rules Marijuana Sales in Colorado But Most Doctors Still in the Dark 4Vittamed Adds Prominent Neurosurgeon and Venture Capitalist T. Forcht Dagi to Board of Directors 2
... Nov. 22, 2011  Colorado Drug Card, in partnership with ... has agreed to be the "Preferred Pharmacy" for the ... to process prescriptions through Colorado Drug Card. Coloradans can ... pharmacist to process their prescription through the Colorado Drug ...
... Nov. 22, 2011 Omeros Corporation (NASDAQ: ... to discovering, developing and commercializing products targeting inflammation, ... today announced that Gregory A. Demopulos, M.D., chairman ... at the 23rd Annual Piper Jaffray Health Care ...
Cached Medicine Technology:
... Craftsmanship have produced the finest ... Ocutek now makes them available ... the coveted Meisterbrief certificate, which ... qualified to become Ocutek instrument ...
... of German Craftsmanship have produced ... the world. Ocutek now makes ... holders of the coveted Meisterbrief ... apprenticeship, are qualified to become ...
... Centuries of German Craftsmanship have ... in the world. Ocutek now ... Only holders of the coveted ... eight-year apprenticeship, are qualified to ...
Medtronic Ophthalmics offers a comprehensive selection of corneal trephine,blades and handles. Handcrafted, sharp, uniform blade edges promote a,symetrical and vertical cut of all corneal layers....
Medicine Products: