Navigation Links
Neurologists identify potential biomarker of cognitive decline for earlier diagnosis of disease
Date:10/31/2011

Researchers from the Department of Neurology at NYU Langone Medical Center identified for the first time that changes in the tissue located at the junction between the outer and inner layers of the brain, called "blurring", may be an important, non-invasive biomarker for earlier diagnosis and the development of new therapies for degenerative brain conditions, such as multiple sclerosis. The study was published in the Oct. 26th issue of the Journal of Neuroscience.

"The findings are significant because this is the first time we have mapped the distinct relationship between blurring of the boundary in the left hemisphere, where verbal language skills are managed, and the impact that changes in this area have on cognitive ability," said Karen Blackmon, PhD, research assistant professor, Department of Neurology and lead author of the study. "The fact that this occurs in healthy brains and appears to be connected with a person's cognitive function has significant implications for our ability to diagnose brain disease earlier and for the potential development of new therapies."

In the study, 32 healthy adults had an MRI scan of their brain. The images were enhanced to highlight the junction between the area of the brain where neurons control cognitive and motor function, or "grey matter", and the area where longer, myelin-insulated axon cells responsible for efficient transmission of electrical signals, or "white matter", exist. When neurons develop incorrectly among the axons (which can happen in-utero or after a brain injury) they are visible as "blurring" along the edge of this junction on an MRI. Blurring is associated with impaired cognitive conditions, such as epilepsy and Alzheimer's disease, but has never been identified in individuals without these conditions.

The researchers administered standardized intelligence tests and scored the participants verbal, visual, and spatial cognitive abilities. These abilities are control
'/>"/>

Contact: Craig Andrews
craig.andrews@nyumc.org
212-404-3511
NYU Langone Medical Center / New York University School of Medicine
Source:Eurekalert

Page: 1 2

Related medicine news :

1. First clinical trial of gene therapy for pain reported by U-M neurologists
2. Neurologists develop software application to help identify subtle epileptic lesions
3. Concussion Should Sideline Athletes: Neurologists
4. US neurologists agree on protocols for treatment of infantile spasms
5. IHME develops fast, affordable ways for countries to better identify causes of death in populations
6. Researchers identify potential risk factors for severe altitude sickness
7. Scientists Identify Gene Linked to Cold Sores
8. Blood test could identify smokers at higher risk for heart disease, UT Southwestern researchers find
9. Mine-hunting software helping doctors to identify rare cells in human cancer
10. New tool helps identify prostate cancer patients with highest risk of death
11. More screening needed to identify depression, vision loss after mild stroke
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/31/2015)... ... August 31, 2015 , ... ... with a ribbon-cutting ceremony on Aug. 26, generously hosted by the Collinsville Chamber ... appointments via AdvantaClean’s National Call Center and website since Aug. 17. , The ...
(Date:8/31/2015)... ... 2015 , ... American Family Care (AFC), the nation’s leading ... in Tennessee with the opening of a new urgent care facility at 9203 ... in Tennessee, and 148th in the U.S. overall. , “We’re excited to continue ...
(Date:8/31/2015)... ... August 31, 2015 , ... Kognito , a ... their competencies in managing challenging conversations, announced today that Glenn Albright, Ph.D., the ... of Excellence for Psychological Health and Traumatic Brain Injury (DCoE) Summit taking ...
(Date:8/31/2015)... ... August 31, 2015 , ... In preparation for this November’s National Family ... BEAN™ personal sound amplifier, is offering caregivers “7 Reasons to Care about Hearing Health.” ... coping with a variety of home healthcare challenges, specifically as they relate to caring ...
(Date:8/31/2015)... ... August 31, 2015 , ... ... for physicians and allied health professionals dedicated to using lifestyle as a ... the establishment of the Lifestyle Medicine Lifetime Achievement and Trailblazer Awards, with ...
Breaking Medicine News(10 mins):Health News:Ribbon Cutting Launches AdvantaClean of Madison County 2Health News:State-of-the-Art Urgent Care Facility Opening in Knoxville 2Health News:Kognito’s Glenn Albright to Present at DCoE Summit 2Health News:Etymotic Offers Caregivers “7 Reasons to Care about Hearing Health” 2Health News:Etymotic Offers Caregivers “7 Reasons to Care about Hearing Health” 3Health News:Nominations Sought for Awards Recognizing Exemplary Contribution to the Field of Lifestyle Medicine 2Health News:Nominations Sought for Awards Recognizing Exemplary Contribution to the Field of Lifestyle Medicine 3
... in human cases of bird flu, causing increasing fear of ... in the scientific community to combat this impending and much ... risen since October 5 when scientists from the U.S. Army ... similarities between the bird flu strain in Asia, called H5N1, ...
... flu pandemic has created a stir worldwide with US President ... developers to speed up the process of developing a vaccine ... than 80 countries and international organizations met in Washington on ... officials including those from the World Health Organization (WHO) have ...
... Online Publication, released on the 5th of October, which ... diseases, has a comprehensive report on the threat of ... by Union Health Minister Dr Anbumani Ramadoss, the need ... challenge of chronic diseases in India was highlighted, stating ...
... Though technologic developments bring social and economic benefits ... are difficult to predict and manage. With rapid ... communications, children are increasingly exposed to EMFs at ... childhood leukemia and exposure to extremely low frequency ...
... found a new gene based test for identifying DNA fusion, ... research team is focusing on detection of genes // linked ... called as Acute Lymphoblastic Leukemia (ALL). The researchers took more ... is given by chemotherapy which kills the leukemia cells and ...
... one of life’s most distressing events, bringing in its wake ... reaction to the disease, but could have grave consequences. Because ... have an impact not only on the progression, but also ... in the ordinary course of human life, have been shown ...
Cached Medicine News:Health News:Strategies to prevent the rising tide of the epidemic of chronic diseases 2Health News:Hazards of Electromagnetic Fields for children 2Health News:Depression May Be A Risk Factor For Cancer Initiation 2
(Date:8/31/2015)... N.J. , Aug. 31, 2015  ... a late-stage biopharmaceutical company developing products that address ... oncology and biodefense, announced today it has completed ... the Data Review Committee (DRC) earlier this year, ... SGX942 is a first-in-class innate defense regulator (IDR) ...
(Date:8/31/2015)... -- Premune and Innovet today ... agreement for Redonyl ® Ultra. The product, which ... dermatology market, is a nutritional supplement based on PEA-um ... dogs and cats. Redonyl ® Ultra is currently ... been received positively in the country by veterinarians and ...
(Date:8/31/2015)... Bionomics Limited (ASX:BNO, ADR:BMICY), a biopharmaceutical company ... for the treatment of diseases of the central nervous ... IND submission has passed review by the US Food ... Phase 1 clinical trial in patients with metastatic colon ... to 31 December 2015. Bionomics, CEO & ...
Breaking Medicine Technology:Soligenix Announces Completion of Patient Enrollment into its Phase 2 Clinical Trial of SGX942 for the Treatment of Oral Mucositis in Head and Neck Cancer Patients 2Soligenix Announces Completion of Patient Enrollment into its Phase 2 Clinical Trial of SGX942 for the Treatment of Oral Mucositis in Head and Neck Cancer Patients 3Soligenix Announces Completion of Patient Enrollment into its Phase 2 Clinical Trial of SGX942 for the Treatment of Oral Mucositis in Head and Neck Cancer Patients 4Soligenix Announces Completion of Patient Enrollment into its Phase 2 Clinical Trial of SGX942 for the Treatment of Oral Mucositis in Head and Neck Cancer Patients 5Soligenix Announces Completion of Patient Enrollment into its Phase 2 Clinical Trial of SGX942 for the Treatment of Oral Mucositis in Head and Neck Cancer Patients 6Premune Broadens Portfolio With Novel Innovet Skin Health Product 2Premune Broadens Portfolio With Novel Innovet Skin Health Product 3Premune Broadens Portfolio With Novel Innovet Skin Health Product 4Successful BNC101 IND Submission Paves Way for Development of Promising Cancer Stem Cell Drug Candidate 2Successful BNC101 IND Submission Paves Way for Development of Promising Cancer Stem Cell Drug Candidate 3Successful BNC101 IND Submission Paves Way for Development of Promising Cancer Stem Cell Drug Candidate 4
... BNVI ), a pharmaceutical company focused on the ... health and cancer, today announced that Dr. Isaac Cohen, O.M.D., ... Cowen and Company 31st Annual Healthcare Conference at 9:30 a.m. ... held at the Boston Marriott Copley Place, in Boston, Massachusetts. ...
... March 7, 2011   PDL BioPharma, Inc. (PDL) ... the first quarter ending March 31, 2011 of approximately $83 ... the first quarter of 2010, an expected 34 percent year-over-year ... million settlement received from UCB Pharma S.A. (UCB) in January ...
Cached Medicine Technology:Bionovo to Present at the Cowen and Company 31st Annual Healthcare Conference 2PDL BioPharma Provides First Quarter 2011 Revenue Guidance of $83 Million 2PDL BioPharma Provides First Quarter 2011 Revenue Guidance of $83 Million 3PDL BioPharma Provides First Quarter 2011 Revenue Guidance of $83 Million 4
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: