Navigation Links
Neuroimaging may offer new way to diagnose bipolar disorder
Date:6/5/2013

MRI may be an effective way to diagnose mental illnesses such as bipolar disorder, according to experts from the Icahn School of Medicine at Mount Sinai. In a landmark study using advanced techniques, the researchers were able to correctly distinguish bipolar patients from healthy individuals based on their brain scans alone. The data are published in the journal Psychological Medicine.

Currently, most mental illnesses are diagnosed based on symptoms only, creating an urgent need for new approaches to diagnosis. In bipolar disorder, there may be a significant delay in diagnosis due to the complex clinical presentation of the illness. In this study, Sophia Frangou, MD, Professor of Psychiatry and Chief of the Psychosis Research Program at the Ichan School of Medicine at Mount Sinai teamed up with Andy Simmons, MD, of the Kings College London and Janaina Mourao-Miranda, MD, of University College London, to explore whether brain imaging could help correctly identify patients with bipolar disorder.

"Bipolar disorder affects patients' ability to regulate their emotions successfully, which puts them at great disadvantage in their lives," said Dr. Frangou. "The situation is made worse by unacceptably long delays, sometimes of up to 10 years, in making the correct diagnosis. Bipolar disorder may be easily misdiagnosed for other disorders, such as depression or schizophrenia. This is why bipolar disorder ranks among the top ten disorders causing significant disability worldwide."

Dr. Frangou and her team used MRI to scan the brains of people with bipolar disorder and of healthy individuals. Using advanced computational models, they were successful in correctly separating people with bipolar disorder from healthy individuals with 73 percent accuracy using their brain imaging scans alone. They replicated their finding in a separate group of patients and healthy individuals and found a 72 percent accuracy rate.

Dr. Simmons added, "The level of accuracy we achieved is comparable to that of many other tests used in medicine. Additionally, brain scanning is very acceptable to patients as most people consider it a routine diagnostic test."

"This approach does not undermine the importance of rigorous clinical assessment and the importance of building relationships with patients but provides biological justification for the type of diagnosis made," said Dr. Frangou. "However, diagnostic imaging for psychiatry is still under investigation and not ready for widespread use. Nonetheless, our results together with those from other labs are a harbinger of a major shift in the way we approach diagnosis in psychiatry."

Dr. Frangou recently joined Mount Sinai as Chief of the Psychosis Research Program in the Division of Psychiatric Genomics in the Department of Psychiatry at Mount Sinai. A leading authority on neuroimaging in schizophrenia and bipolar disorder, Dr. Frangou was recruited to Mount Sinai to establish a clinical and translational psychosis program. By building on Mount Sinai's strengths in clinical investigation, the program aims to translate research in genetics, neuroimaging, and neurobiology into clinical trials and clinical care.


'/>"/>

Contact: Mount Sinai Press Office
newsmedia@mssm.edu
212-241-9200
The Mount Sinai Hospital / Mount Sinai School of Medicine
Source:Eurekalert

Related medicine news :

1. Neuroimaging study: Negative messages less effective on those who are substance dependent
2. Entrepreneur offers Tips on How to Live in Paradise and Run a Business from the Cayman Islands
3. hCGTreatments / Diet Doc hCG Diets & Weight Loss Plans Offer Newly Designed hCG Diet Plans that Aid Patients in Receiving Improved Medical Care
4. Top NYC Chiropractor Dr. Steven Shoshany Offers Complimentary Sciatica Summer Promotion
5. A2LA Offers Training Course on the ISO/IEC 17065 Standard for Product Certification Bodies
6. Sublime Beauty® Introduces"Face Whisperer® Day Cream" With Argireline (Known as the Natural Botox®); One Day Introductory Offer of 50% Off Today Only (Only $23.40)
7. Hair Loss Treatment Solutions Now Offered to Balding Men Online at HomeRemediesforHairLoss.net
8. Las Vegas Varicose Vein Care Specialist Five Star Vein Institute Offers the Veinwave
9. NorthernCaliforniaDrugRehab.com Offers New Hope for Addicts and their Families
10. hCGTreatments / Diet Doc hCG Diets & Weight Loss Plans Offers New Improved hCG Diet Plans Capable of Natural Weight Loss for Heartburn Relief
11. Caplugs Now Offers Shercon Masking Products
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/2/2016)... ... December 02, 2016 , ... ... build intelligent, connected applications, was named the best Sales Team of 2016 as ... announcement was made today by the Software & Information Industry Association (SIIA), the ...
(Date:11/30/2016)... ... November 30, 2016 , ... The Fertility ... designated as a Cigna Infertility Center of Excellence. The Cigna Center of Excellence ... “It’s an honor to be designated a Cigna Infertility Center of Excellence," said ...
(Date:11/30/2016)... ... 2016 , ... Standard Process, Inc. is proud to announce ... of the largest closely held companies headquartered in Wisconsin. This marks the company’s ... Process was awarded the Talent Award for providing outstanding employee benefits. , ...
(Date:11/30/2016)... ... November 30, 2016 , ... In ... been a focus of public policymakers and system stakeholders in many states. To ... its Medical Price Index for Workers’ Compensation, Eighth Edition (MPI-WC) . , ...
(Date:11/30/2016)... ... November 30, 2016 , ... ... its orthopedic practice with the addition of new North Phoenix and Chandler locations. ... C. Lincoln North Mountain campus at 9327 North 3rd St, Suite 300 in ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... , Dec. 2, 2016  PipelineRx, a leading medication ... be offering demonstrations of its SaaS-based telepharmacy platform, ... Health-System Pharmacists 2016 Midyear Clinical Meeting and Exhibition, ... . With nearly 300 hospital clients nationally, the ... technology designed to dramatically improve pharmacy operations, enhance ...
(Date:12/2/2016)... On Thursday, December 1st 2016, ... research, development and innovation in the biopharmaceutical industry at ... in the presence of Sergey Tsyb, Vice Minister of ... , Natalia Sanina, First Vice Chairman of the ... of Roszdravnadzor, National Service of Control in Healthcare, Sergey ...
(Date:12/2/2016)... , Dec. 2, 2016  Eli Lilly and ... financial guidance for 2017 and provide updated financial guidance ... also conduct a conference call on that day with ... company,s financial guidance. The conference call will ... general public can access a live webcast of the ...
Breaking Medicine Technology: