Navigation Links
Neuroimaging: Live from inside the cell
Date:4/22/2014

This news release is available in German.

Reactive oxygen species are important intracellular signaling molecules, but their mode of action is complex: In low concentrations they regulate key aspects of cellular function and behavior, while at high concentrations they can cause "oxidative stress", which damages organelles, membranes and DNA. To analyze how redox signaling unfolds in single cells and organelles in real-time, an innovative optical microscopy technique has been developed jointly by the teams of LMU Professor Martin Kerschensteiner and TUM Professor Thomas Misgeld, both investigators of the Munich Cluster for Systems Neurology (SyNergy).

"Our new optical approach allows us to visualize the redox state of important cellular organelles, mitochondria, in real time in living tissue" Kerschensteiner says. Mitochondria are the cell's power plants, which convert nutrients into usable energy. In earlier studies, Kerschensteiner and Misgeld had obtained evidence that oxidative damage of mitochondria might contribute to the destruction of axons in inflammatory diseases such as multiple sclerosis.

The new method allows them to record the oxidation states of individual mitochondria with high spatial and temporal resolution. Kerschensteiner explains the motivation behind the development of the technique: "Redox signals have important physiological functions, but can also cause damage, for example when present in high concentrations around immune cells."

First surprises

Kerschensteiner and Misgeld used redox-sensitive variants of the Green Fluorescent Protein (GFP) as visualization tools. "By combining these with other biosensors and vital dyes, we were able to establish an approach that permits us to simultaneously monitor r
'/>"/>

Contact: Vera Siegler
vera.siegler@tum.de
49-892-892-2731
Technische Universitaet Muenchen
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Corporate Whistle Blower Center Now Urges Medical Device Insiders To Be A Whistleblower If They Can Prove The Device Maker Knew Of A Failure & Said Nothing=Huge Rewards
2. Video shows the traffic inside a brain cell
3. Parents skin cancer concern doesnt keep kids inside
4. Smart scaffolding aims to rebuild tissue from the inside
5. New MRI technology to provide even better images of the inside of the human body
6. Corporate Whistle Blower Center Now Urges Medical Industry Insiders to Blow the Whistle if They Can Prove a Medical Product was Defective and Their Company Sold it Anyway
7. Skin Authority Creates One-of-a-Kind Solution for the One Billion People Worldwide Who are Vitamin D Deficient -- Groundbreaking Launch of "Inside Out" System
8. Prime Medical Associates’ Sleep Lab Featured in Insider Magazine
9. Corporate Whistle Blower Center Now Urges Physicians, Medical Device or Drug Insiders With Proof A Company Knowingly Sold A Bad Product to Become a Whistleblower
10. Corporate Whistle Blower Center Now Urges Physicians Medical Device and Drug Industry Insiders To Step Up-If They Have Proof Of Serious Wrongdoing or Overbilling
11. Fitness Celebrity and one of Canada’s Inside Fitness Hot and Fit Women of 2012, Nancy Di Nino, brings her Media Personality to host the Hot & Fit Release Party
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Neuroimaging: Live from inside the cell
(Date:9/3/2014)... 03, 2014 "What can you say about ... "Margaret and Hillary," Book Eight in the Margaret of ... published by Wyston Books, Inc . These novels narrate ... in the richest town in America. , In this thriller, ... helps to investigate a student’s murder plot. Her fears increase ...
(Date:9/2/2014)... Autumn is well under way and famous review ... with worldwide people. Recently, it has made a ... http://secure.hostgator.com/~affiliat/cgi-bin/affiliates/clickthru.cgi?id=seohosts ), Arvixe, and Bluehost are the best ... 2002 HostGator has been known as a top ... reliability remains with it today. It is offering ...
(Date:9/2/2014)... today,s concentrated pot might be risky business for ... University. The study is the first to demonstrate ... THC. , Psychology professor Rebecca Craft showed ... are at least 30 percent more sensitive than ... active ingredient in cannabis. Females also develop tolerance ...
(Date:9/2/2014)... 2014 http://topcreatinemonohydrate.com/ , a ... obtain the latest information about muscle and fitness ... focuses mainly on testosterone and creatine ... their workout capacity and improve their athletic performance. ... Creatine Monohydrate, Muscle Advance Creatine is one of ...
(Date:9/2/2014)... Illinois (PRWEB) September 02, 2014 ... Chief Executive Officer and Chief Information Officer Strategy ... Carlton Chicago. , Becker's Hospital Review Chief Executive ... together hospital and health system Chief Executive Officers, ... hospital and health system executives through high-quality ...
Breaking Medicine News(10 mins):Health News:Town Locked Down After Bombing and Murders in "Margaret and Hillary" - New Book Eight in the Margaret of Greenwich(R) Young Adult Series by R. L. Rhyse 2Health News:Top10BestSEOHosting.com Celebrates The Coming Of Autumn And Release Reseller Hosting Suppliers Of 2014 2Health News:Estrogen increases cannabis sensitivity 2Health News:Estrogen increases cannabis sensitivity 3Health News:Creatine Monohydrate Reviews Site TopCreatineMonohydrate.com Announces its Launch 2Health News:Becker's Healthcare Announces Hospital CEO and CIO Strategy Roundtables 2Health News:Becker's Healthcare Announces Hospital CEO and CIO Strategy Roundtables 3Health News:Becker's Healthcare Announces Hospital CEO and CIO Strategy Roundtables 4
... An article appearing in the January issue of The Journal ... cancers (GISTs) are likely to be ineffective for// patients with ... reported by investigators at the Mayo Clinic Cancer Center, who ... help patients with high grade renal cell carcinoma. "While this ...
... are developing a hands-free frame, which may help stroke patients ... ,Stroke is a leading cause of adult disability in England ... ,Existing frames require the person to hold them ... cannot use these, and often need two people to support ...
... Research Center has reported that maintaining the current recommended ... of cardiovascular disease. The researcher has asked the ... patients less than the recommended levels by aggressive blood ... is used to monitor the average amount of blood ...
... way of treating psychological disorders. Carl Rogers introduced this technique ... lot of questions about this technique. But it was one ... patients from a different perspective. ,It was contradictory ... this therapy is not widely accepted by many psychologists. ...
... can do to people. High-fat diets cause many patients' problems. ... to know what they consume. ,Now, new rules on ... trans fats, which plug arteries, and have been linked to ... ,Trans fats are a result of manufacturers adding hydrogen ...
... or obese have a greater risk of developing Alzheimer’s, the ... researchers // has claimed. ,The research team ... Cowan University in Western Australia - say that being obese ... have found a link between body mass index (BMI) and ...
Cached Medicine News:Health News:New Gastric Cancer Drug Unlikely to Benefit Kidney Cancer Patients 2Health News:Food labels to include information on trans fats in US 2Health News:Food labels to include information on trans fats in US 3Health News:Obesity could lead to Alzheimer's 2
(Date:9/2/2014)...  Reportlinker.com announces that a new market research report ... and Taiwanese Markets for Minimally Invasive Spinal Devices ... The market for MIS spinal devices in the ... at a fast pace, albeit at different rates in ... China , where MIS spinal fusion ...
(Date:9/2/2014)... , Sept. 2, 2014 The Pharmaceutical Care ... benefit managers (PBMs), today filed a lawsuit in ... new Iowa law that restricts ... for the state,s employers and consumers.  ... by severely restricting the use of Maximum Allowable Cost ...
(Date:9/2/2014)... 2, 2014  XBiotech announced today interim results ... in the US for its anti-cancer agent Xilonix™. ... therapy, is being evaluated in advanced colorectal cancer ... The primary endpoint of the study is overall ... a control population provided only palliative therapy for ...
Breaking Medicine Technology:Chinese and Taiwanese Markets for Minimally Invasive Spinal Devices 2Chinese and Taiwanese Markets for Minimally Invasive Spinal Devices 3Chinese and Taiwanese Markets for Minimally Invasive Spinal Devices 4Chinese and Taiwanese Markets for Minimally Invasive Spinal Devices 5Chinese and Taiwanese Markets for Minimally Invasive Spinal Devices 6Chinese and Taiwanese Markets for Minimally Invasive Spinal Devices 7Chinese and Taiwanese Markets for Minimally Invasive Spinal Devices 8Chinese and Taiwanese Markets for Minimally Invasive Spinal Devices 9Lawsuit Challenges Iowa Health Mandate that Forces Employers to Pay More for Prescription Drugs 2XBiotech Halts Study, Reports Positive Phase III Results with Antibody Therapy for Cancer 2
... SEOUL, South Korea, Feb. 16, 2012   ,The ... the largest health care provider festival, is ... This Exhibition, for enhancing a national ... of hospital-related industry, is hosted by Korea ...
... Therapeutics, Inc. (NASDAQ: HALO ) today announced the ... its common stock, including 1,020,000 shares sold pursuant to the ... underwriter. All of the shares were offered by Halozyme at ... proceeds to Halozyme from this offering were approximately $81.8 million, ...
Cached Medicine Technology:To Take a Glance Cutting Edge Medicine Equipment! 'The 28th International Medical & Hospital Equipment Show' 2To Take a Glance Cutting Edge Medicine Equipment! 'The 28th International Medical & Hospital Equipment Show' 3Halozyme Announces Exercise in Full of Over-Allotment Option and Completion of Public Offering of Stock 2Halozyme Announces Exercise in Full of Over-Allotment Option and Completion of Public Offering of Stock 3
... synergy T-EP Developed in collaboration with ... and an exceptionally high standard of ... Multimedia technology and design expertise to ... 2, 5 or 10-channel Medelec Synergy ...
Neuropack Sigma MEB-5500 series evoked potential measuring system is a compact, portable, all-in-one unit....
The Nicolet Bravo is a Multi-application system that can configure to meet the needs of neurophysiology deparent....
... of the MYOHANDY family are probably ... MYOQUICK - SystemPLUS line. Based on ... systems of the ISA 100x EP ... ISA 1002 EP) , 4 channels ...
Medicine Products: