Navigation Links
Neuralstem stem cells survive and differentiate into neurons in rats with stroke
Date:9/14/2010

ROCKVILLE, Maryland, September 14, 2010 Neuralstem, Inc. (NYSE Amex: CUR) announced that its spinal cord stem cells survived in rat brains affected by stroke and differentiated predominantly into neurons. The transplanted animals showed significant improvement in some motor skill and strength measurements. The study entitled, "Intracerebral Implantation of Adherent Human Neural Stem Cells To Reverse Motor Deficits in Chronic Stroke Rats," was presented earlier today by senior study author, Dr. Shinn-Zong Lin, M.D., Ph.D., at the Stem Cells USA & Regenerative Medicine Conference (http://www.terrapinn.com/2010/stemcellsusa/conf.stm), in Philadelphia, PA. Dr. Lin is a Professor of Neurosurgery and Vice Superintendent at China Medical University Hospital of Taiwan.

"This animal study shows the potential promise of this cell line in treating post-stroke symptoms," Dr. Lin commented. "Four weeks after transplantation, the rats treated with Neuralstem's cells showed significantly decreased asymmetric body swing, increased vertical movements and increased grip strength, compared with the control group."

"Dr. Lin's findings represent a significant milestone for Neuralstem. They are the first to show how our human spinal cord-derived stem cell product, NSI-566RSC, currently in a clinical trial for ALS, and which we expect to be in another clinical trial for spinal cord injury, also works in the stroke brain," said Dr. Karl Johe, Ph.D., Neuralstem's Chief Scientific Officer and Chairman of the Board of Directors. "Our proposed treatment for paralysis due to stroke will involve transplantation near the motor tracts close to the stroke lesion in the brain in order to promote regeneration and repair. While the trial protocol for ALS and chronic spinal cord injury involves transplantation into the spinal cord, and that for stroke will involve transplantation into the brain, we are nevertheless targeting the circuitry that controls motor function in each indication. We are developing clinical programs for stroke in both the U.S. and Taiwan, and hope to start our first trial in 2011."


'/>"/>

Contact: Deanne Eagle
deanneeagle@gmail.com
917-837-5866
Neuralstem, Inc.
Source:Eurekalert

Related medicine news :

1. Neuralstem files FDA application for first chronic spinal cord injury stem cell trial
2. Neuralstem updates clinical trial progress
3. K-State receives patent for noncontroversial source of stem cells
4. In-depth investigation on the capacity of 4-HPR to induce death of tumor cells
5. These cells will self-destruct in 5 ... 4 ...
6. Basal-like breast cancer does not originate from basal stem cells
7. Scientists unwrap DNA packaging to gain insight into cells
8. For the first time, researchers identify and isolate adult mammary stem cells in mice
9. Use the common cold virus to target and disrupt cancer cells?
10. Study of cell division sheds light on special mechanism in egg cells
11. Human neural stem cells restore motor function in mice with chronic spinal cord injury
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/12/2016)... ... February 12, 2016 , ... Healthcare careers in the medical laboratory, nursing, and ... the website of healthcare staffing leader Aureus Medical Group during the month of January. ... travel therapy positions and in travel and direct hire opportunities in other allied ...
(Date:2/12/2016)... ... ... Yisrayl Hawkins, Pastor and Overseer at The House of Yahweh in Abilene, Texas, ... real facts surrounding all those Bible stories. For generations families have gathered to hear ... says there is more to these than just mere “stories”. , The article ...
(Date:2/12/2016)... ... 12, 2016 , ... With the exception of restorative dentistry, to date there has been no ... recent approval by the FDA, there is a now a new protocol in stopping cavity ... very simple and quick to apply. The application is as simple as drying the ...
(Date:2/11/2016)... ... February 11, 2016 , ... “ HEALING MIND : ... a Well Managed Mind” (published by Balboa Press) teaches readers how to become their ... through profound love, author Janice McDermott, M.Ed., LCSW, offers an understanding of how to ...
(Date:2/11/2016)... ... February 11, 2016 , ... Student-doctors ... Osteopathic Association’s (AOA) Match Program Tuesday, February 9, taking one of the final ... osteopathic graduate medical education positions across the country. Of the 103 student-doctors who ...
Breaking Medicine News(10 mins):
(Date:2/11/2016)... Feb. 11, 2016 Brain Cancer patients ... method at West Cancer Center . Optune™, ... to inhibit cancer cell replication causing death of cancer ... a decade to show a significant extension in overall ... patients. Currently, West Cancer Center is the only medical ...
(Date:2/11/2016)... , Feb. 11, 2016  AbbVie, a ... AbbVie Rheumatology Scholarship, designed to provide financial support ... as they pursue higher education goals. Fifteen scholars ... the 2016-2017 school year. The AbbVie Rheumatology Scholarship ... Haas , vice president, corporate social responsibility, brand ...
(Date:2/11/2016)... -- PLAD, Inc. (OTC Pink: PLAD) is pleased to announce that ... targets, are adding key personnel to their national sales ... States Patent and Trademark Office for the characters "P.L.A.D.".    ... PLAD, Inc.  In January, PLAD established their presence in ... two new customers, Cumberland Goodwill EMS and Meadville Ambulance, ...
Breaking Medicine Technology: