Navigation Links
Nerve damage may underlie widespread, unexplained chronic pain in children
Date:3/11/2013

en described. To get a better sense of the possible contribution of SFPN to chronic pain in children, Oaklander and her co-author Max Klein, PhD, a research fellow in Neurology at MGH, reviewed the records of 41 patients treated by Oaklander between 2007 and 2011 for persistent widespread pain in several parts of the body that began before age 21. In a search for the cause of their symptoms, all of the patients had undergone a range of diagnostic tests at the MGH and other leading institutions.

Recommended diagnostic tests for SFPN include a type of skin biopsy that characterizes the number and condition of nerve fibers in the lower leg and autonomic function testing, including monitoring the heart rate and blood pressure when an individual breaths deeply, blows out when the airway is blocked or is placed on a tilt table. A control group of 38 age- and gender-matched volunteer children underwent the same autonomic function tests that the patients had received, and control values for neurodiagnostic skin biopsies were based on samples from healthy age- and gender-matched volunteers collected at MGH.

The analysis revealed that 24 of the 41 patients met criteria for a diagnosis of SFPN, meaning that results of at least one test clearly indicated the presence of the disease. Of the remaining 17 patients, 16 were determined to possibly or probably have SFPN, based on less seriously abnormal test results. Among the autonomic function tests, sweat production a sensitive diagnostic test for SFPN was reduced in 82 percent of patients, compared with 34 percent of controls. In contrast, results of other tests that the patients had undergone including magnetic resonance imaging, spinal taps and gastrointestinal endoscopy provided no useful diagnostic information.

Many of the patients participating in the study had reported that their symptoms began after an earlier illness or injury. A third had some history of autoimmune illnesses, and
'/>"/>

Contact: Mike Morrison
mdmorrison@partners.org
617-724-6425
Massachusetts General Hospital
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. New technique may help severely damaged nerves regrow and restore function
2. New embryonic stem cell line will aid research on nerve condition
3. How does exercise affect nerve pain?
4. Exercise Appears to Ease Nerve-Damage Pain in Rat Study
5. Sleep Apnea May Be Linked to Nerve Damage in Diabetics
6. Nerve growth factors elevated in pancreatic cancer model
7. New candidate drug stops cancer cells, regenerates nerve cells
8. Miami Children’s Hospital Performs First Nerve Repair Surgery Using Avance® Nerve Graft Technology
9. Taking the fate of stem cells in hand: RUB researchers generate immature nerve cells
10. JAAOS study highlights success of nerve transfer surgery
11. Long-term methadone treatment can affect nerve cells in brain
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2015)... ... 2015 , ... North American Seminars will present seventeen ... . These seventeen courses are pre-approved for CME credit for Physical therapists, ... the Older Adult , August 22, 2015 - August 23, 2015 presented ...
(Date:7/28/2015)... Orange, NJ (PRWEB) , ... July 28, 2015 , ... ... on the sidelines – or in your easy chair? Luckily, there are plenty of ... Kadimcherla, MD , an orthopedic spine surgeon at Atlantic Spine Center . ...
(Date:7/28/2015)... ... ... President of the Veterans Fund of the United States, managing the United Veteran Beacon House ... a campaign to help homeless Veterans by giving them “A hand up – not a ... the UVBH assists and supports Vets through the Veterans Fund of the United States ...
(Date:7/27/2015)... ... ... Dr. Robert G. Schwartz , principal of Greenville, SC-based Piedmont Physical Medicine ... in order to offer his patients a new system of care utilizing laser therapy ... Peripheral neuropathy is a disease caused by damage to the peripheral nerves, and typically ...
(Date:7/27/2015)... ... July 28, 2015 , ... Combination Product GMP Compliance:, Understanding FDA’s ... EDT, http:// http://www.fdanews.com/comboproductgmpcompliance , Manufacturing a drug or device is ... things can get messy in a hurry. In a 46-page draft guidance released in ...
Breaking Medicine News(10 mins):Health News:North American Seminars receives California PT Board approval for Seventeen Continuing Education Courses presented in the Fall of 2015. 2Health News:North American Seminars receives California PT Board approval for Seventeen Continuing Education Courses presented in the Fall of 2015. 3Health News:North American Seminars receives California PT Board approval for Seventeen Continuing Education Courses presented in the Fall of 2015. 4Health News:North American Seminars receives California PT Board approval for Seventeen Continuing Education Courses presented in the Fall of 2015. 5Health News:North American Seminars receives California PT Board approval for Seventeen Continuing Education Courses presented in the Fall of 2015. 6Health News:North American Seminars receives California PT Board approval for Seventeen Continuing Education Courses presented in the Fall of 2015. 7Health News:North American Seminars receives California PT Board approval for Seventeen Continuing Education Courses presented in the Fall of 2015. 8Health News:Safe Cardio for Back Pain Sufferers 2Health News:Safe Cardio for Back Pain Sufferers 3Health News:Veterans Fund of the United States Launches “Adopt A Homeless Veteran” Campaign 2Health News:Veterans Fund of the United States Launches “Adopt A Homeless Veteran” Campaign 3Health News:Piedmont Physical Medicine & Rehabilitation, P.A. Partners with Realief® Neuropathy Centers to Offer Peripheral Neuropathy Laser Treatment 2Health News:FDAnews Announces — Combination Product GMP Compliance: Understanding FDA’s New Streamline Approach Webinar, Aug. 19, 2015 2Health News:FDAnews Announces — Combination Product GMP Compliance: Understanding FDA’s New Streamline Approach Webinar, Aug. 19, 2015 3Health News:FDAnews Announces — Combination Product GMP Compliance: Understanding FDA’s New Streamline Approach Webinar, Aug. 19, 2015 4
... progression, mouse study suggests , , MONDAY, April 14 (HealthDay ... cholesterol and one is an anti-inflammatory -- may be ... presented at the American Association for Cancer Research annual ... and the statin Lipitor, when used together or alone, ...
... Kimmel Cancer Center at Thomas Jefferson University in ... blood pressure medications might help prevent the spread ... laboratory that one type of pressure-lowering drug called ... growth and causes cell death. , In earlier ...
... Real-Time In Vivo Data via Quantitative ... ... Inc., a leader,in fluorescence in vivo imaging, today announced the commercial ... is based on VisEn,s,proprietary Fluorescence Molecular Tomography (FMT(TM)) technology,platform, and combined ...
... 14 HealthFusion, a,national clearinghouse for ... center operation customer satisfaction excellence under ... Center Program(SM). This distinction,acknowledges a strong ... to provide "An Outstanding Customer Service ...
... As the first of the,nation,s 78 million baby boomers ... health care work force that is too small and ... new report from the Institute of,Medicine. The report calls ... providers -- not just specialists -- in the basics ...
... Denise Kehoe has joined,medication therapy management (MTM) company ... new role, she will manage and oversee the,expansion ... the country., Kehoe brings more than 15 ... PharmMD. She recently served as national strategic,executive of ...
Cached Medicine News:Health News:Celebrex Plus Lipitor Could Fight Prostate Cancer 2Health News:Celebrex Plus Lipitor Could Fight Prostate Cancer 3Health News:Blood pressure drugs halt pancreatic cancer cell growth, Jefferson researchers find 2Health News:VisEn Medical Launches FMT(TM) 2500 - Next-Generation Fluorescence Imaging System 2Health News:J.D. Power and Associates Reports: HealthFusion Recognized for Providing an Outstanding Customer Service Experience 2Health News:J.D. Power and Associates Reports: HealthFusion Recognized for Providing an Outstanding Customer Service Experience 3Health News:Health Care Work Force Too Small, Unprepared for Aging Baby Boomers; Higher Pay, More Training, and Changes in Care Delivery Needed to Avert Crisis 2Health News:PharmMD Announces Denise Kehoe as Vice President of Business Development 2
(Date:7/27/2015)... and PARIS , July 28, 2015 ... Sanofi have entered into a new global collaboration to ... the emerging field of immuno-oncology. As part of the ... cell death protein 1 (PD-1) inhibitor currently in Phase ... 2016 with new therapeutic candidates based on ongoing, innovative ...
(Date:7/27/2015)... United Kingdom , July 27, 2015 /PRNewswire/ ... a leading specialty biopharmaceutical company, announced today that ... which it will sell its global contrast media ... NYSE Euronext) in a transaction valued at approximately ... divest its CMDS business is consistent with the ...
(Date:7/27/2015)... and PITTSBURGH , July 27, ... that it will hold its extraordinary general meeting of shareholders ... (NYSE: PRGO ; TASE) at the Okura Hotel Amsterdam ... Time (CET). Among other agenda items at ... on the approval, under article 2:107a of the Dutch Civil ...
Breaking Medicine Technology:Regeneron and Sanofi Launch Major New Immuno-Oncology Collaboration 2Regeneron and Sanofi Launch Major New Immuno-Oncology Collaboration 3Regeneron and Sanofi Launch Major New Immuno-Oncology Collaboration 4Regeneron and Sanofi Launch Major New Immuno-Oncology Collaboration 5Regeneron and Sanofi Launch Major New Immuno-Oncology Collaboration 6Regeneron and Sanofi Launch Major New Immuno-Oncology Collaboration 7Regeneron and Sanofi Launch Major New Immuno-Oncology Collaboration 8Mallinckrodt Enters Agreement To Sell Its Contrast Media And Delivery Systems Imaging Business To Guerbet For $270 Million 2Mallinckrodt Enters Agreement To Sell Its Contrast Media And Delivery Systems Imaging Business To Guerbet For $270 Million 3Mallinckrodt Enters Agreement To Sell Its Contrast Media And Delivery Systems Imaging Business To Guerbet For $270 Million 4Mallinckrodt Enters Agreement To Sell Its Contrast Media And Delivery Systems Imaging Business To Guerbet For $270 Million 5Mallinckrodt Enters Agreement To Sell Its Contrast Media And Delivery Systems Imaging Business To Guerbet For $270 Million 6Mallinckrodt Enters Agreement To Sell Its Contrast Media And Delivery Systems Imaging Business To Guerbet For $270 Million 7Mylan Announces Meeting Date and Record Date of Extraordinary General Meeting of Shareholders 2Mylan Announces Meeting Date and Record Date of Extraordinary General Meeting of Shareholders 3Mylan Announces Meeting Date and Record Date of Extraordinary General Meeting of Shareholders 4Mylan Announces Meeting Date and Record Date of Extraordinary General Meeting of Shareholders 5Mylan Announces Meeting Date and Record Date of Extraordinary General Meeting of Shareholders 6Mylan Announces Meeting Date and Record Date of Extraordinary General Meeting of Shareholders 7Mylan Announces Meeting Date and Record Date of Extraordinary General Meeting of Shareholders 8Mylan Announces Meeting Date and Record Date of Extraordinary General Meeting of Shareholders 9Mylan Announces Meeting Date and Record Date of Extraordinary General Meeting of Shareholders 10
... 2011 Double Eagle Holdings, Ltd. (OTCQB: ... www.fusescience.com ), announced today that it has entered into ... Inc. (PDT Inc.), a California-based pharmaceutical consulting firm. Double ... Inc., the developer of new, patent-pending technologies poised to ...
... the worldwide leader in 3D Molecular Breast Imaging (MBI), ... the Naviscan Board of Directors. Dr. Cheng ... in the medical device industry.  He served as the ... Inc.  After acquisition by Ethicon, Inc., a Johnson & ...
Cached Medicine Technology:Double Eagle Holdings Enters Into Supply Agreement with Platform Delivery Technologies Inc. 2Double Eagle Holdings Enters Into Supply Agreement with Platform Delivery Technologies Inc. 3Naviscan Further Strengthens its Board of Directors With the Addition of Dr. Andre Cheng 2
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: