Navigation Links
Nerve Tissue Cancer More Often Fatal for Non-White Kids
Date:11/24/2010

TUESDAY, Nov. 23 (HealthDay News) -- Black, Asian American and Native American children with neuroblastoma are more likely to die after treatment than white or Hispanic children with this type of cancer, which forms in nerve tissue.

That's the conclusion of an analysis of more than 3,500 children diagnosed with the disease between 2001 and 2009. It also found that black and Native American children are more likely to have the high-risk form of neuroblastoma and to show signs of resistance to modern treatment.

The findings suggest that genetic factors play a role in racial disparities found in outcomes for neuroblastoma patients, said the researchers.

They found that:

  • Rates of survival five years after diagnosis were: 75 percent for whites and Hispanics; 67 percent for blacks; 63 percent for Asians; and 39 percent for Native Americans.
  • Black patients were more likely than whites to have high-risk disease -- 57 percent vs. 44 percent.
  • Black patients were also more likely to have individual predictors of high-risk neuroblastoma, including older age at diagnosis, stage 4 disease, and unfavorable histology.

"By definition, if you are older and have advanced stage disease, you are at high risk for relapse and more difficult to cure," senior author Dr. Susan Cohn, a professor of pediatrics at Comer Children's Hospital at the University of Chicago Medical Center, said in a UCMC news release. "The major reason why the black patients do worse is because there are more of them in this high-risk group."

She and her colleagues also found that black patients were much more likely than whites to suffer a "late-occurring" event after being event-free for two years following diagnosis. This suggests that black patients are more likely to have residual cancer after treatment, Cohn said.

The study appears online Nov. 22 in the Journal of Clinical Oncology.

The same issue includes a study by researchers who say they have identified six subtypes of medulloblastoma, one of the most common malignant brain tumors in children. Medulloblastomas carry a death rate of 40 percent to 50 percent.

The findings could lead to biomarker tests that would help doctors improve their ability to direct treatment.

"We're basically redefining the disease," senior author Dr. Scott Pomeroy, neurologist-in-chief at Children's Hospital Boston, said in a hospital news release. "This tumor breaks down into subtypes that really act like different diseases, and they will be treated differently looking forward."

More information

The American Cancer Society has more about neuroblastoma.

-- Robert Preidt

SOURCES: University of Chicago Medical Center, Children's Hospital Boston, news releases, Nov. 22, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Nerve Zap to Kidneys Might Ease Stubborn Hypertension
2. Burning pain and itching governed by same nerve cells
3. Smoked Marijuana May Ease Chronic Nerve Pain
4. Scientists find link in humans between nerve cell production, memory
5. In breakthrough, nerve connections are regenerated after spinal cord injury
6. $1.9 million grant to help UCF find multiple sclerosis nerve-ana
7. New UCSF Studies Reveal that Age-Related Nerve Decline is Associated with Inflammation and Differs by Gender
8. Study: Mechanomyography to be accurate in detecting nerves during minimally invasive spine surgery
9. Stanford researchers first to turn normal cells into 3-D cancers in tissue culture dishes
10. Scientists develop method to keep surgically-removed prostate tissue alive and working for week
11. IU researchers: Chemotherapy alters brain tissue in breast cancer patients
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Nerve Tissue Cancer More Often Fatal for Non-White Kids 
(Date:6/25/2016)... ... June 25, 2016 , ... Experts ... applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, at the Hynes Convention ... health care topics including advance care planning, healthcare costs and patient and family ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern Californian, ... and his M.D from the David Geffen School of Medicine at UCLA. He trained ... Angeles to complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where ...
(Date:6/24/2016)... ... June 24, 2016 , ... Those who have experienced traumatic events ... turn to unhealthy avenues, such as drug or alcohol abuse, as a coping mechanism. ... tools for healthy coping following a traumatic event. , Trauma sufferers tend to feel ...
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. Amanda Cheng, ... treatment. Dr. Cheng has extensive experience with all areas of orthodontics, including robotic ... osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. It ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Haute ... Dr. Barry M. Weintraub as a prominent plastic surgeon and the network’s newest ... world, and the most handsome men, look naturally attractive. Plastic surgery should be ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... 2016  VMS Rehab Systems, Inc. ( www.vmsrehabsystemsinc.com ) ... measures required to build a strong and stable market ... listed on the OTC Markets-pink current trading platform. ... "We are seeing an anomaly in market trading activities ... by the Company, but shareholders and market players as ...
(Date:6/24/2016)... Calif. , June 24, 2016  Global ... a biopharmaceutical company developing novel therapeutics for the ... needs, today announced the closing of its previously ... common stock, at the public offering price of ... the offering were offered by GBT. GBT estimates ...
(Date:6/24/2016)... June 24, 2016 The Academy of Managed ... recommendations that would allow biopharmaceutical companies to more ... that make formulary and coverage decisions, a move that ... new medicines. The recommendations address restrictions in ... on the drug label, a prohibition that hinders decision ...
Breaking Medicine Technology: