Navigation Links
Negative effects of sleep restriction may linger after 1 night of recovery sleep

DARIEN, Ill. A study in the Aug. 1 issue of the journal Sleep suggests that a dose of extra sleep on the weekend may be good medicine for adults who repeatedly stay up too late or wake up too early during the workweek. However, even a night of 10 hours in bed may not be enough to cure the negative effects of chronic sleep restriction.

Results show that neurobehavioral impairments such as increased lapses of attention and delayed reaction times accumulated across a period of five days when sleep was restricted to less than four hours per night. Behavioral, subjective and physiological measures of alertness improved significantly after a night of recovery sleep, with larger doses of sleep producing greater gains. Yet some neurobehavioral deficits continued to linger after the maximum recovery dose of 10 hours in bed, during which participants slept for an average of about nine hours. The study suggests that complete recovery from sustained sleep restriction may require even more sleep during one night or multiple nights of extended sleep.

"Recovery of alertness dimensions was remarkably dependent on the duration of the recovery time in bed," said principal investigator David F. Dinges, PhD, director of the Unit for Experimental Psychiatry and chief of the Division of Sleep and Chronobiology at the University of Pennsylvania School of Medicine in Philadelphia, Pa. "However, the sleep restriction was severe enough that recovery of alertness was not complete following a single night of extended sleep, indicating a residual sleep debt remained. Lifestyles that involve chronic sleep restriction during the workweek and during days off work may result in continuing buildup of sleep pressure and in an increased likelihood of loss of alertness and increased errors."

The study involved 159 healthy adults with a mean age of 30 years, which is the largest number of subjects to be involved in a single laboratory-based, sleep-restriction experiment. Fifty-seven percent of participants were African-American. Following two baseline nights of 10 hours time in bed, 142 participants were randomized to the sleep restriction protocol of four hours in bed from 4 a.m. to 8 a.m. for five consecutive nights. Then they were randomized to one of six doses of recovery sleep ranging from zero hours to 10 hours in bed for one night. The other 17 participants were randomized to a control group and spent 10 hours in bed on all nights.

Beginning at 8 a.m. each day, participants completed 30-minute computerized neurobehavioral assessments every two hours during scheduled periods of wakefulness. Assessments included a 10-minute Psychomotor Vigilance Test and the Karolinska Sleepiness Scale. A modified Maintenance of Wakefulness Test also was conducted at baseline, on the fifth day of sleep restriction and on the recovery day.

Mean total sleep time dropped from 8.47 hours at baseline to 3.72 hours on the first night of sleep restriction. Relative to the control group, sleep restriction degraded all neurobehavioral functions across the five days of sleep loss. One night of recovery sleep then improved all neurobehavioral outcomes as sleep doses increased. However, lapses of attention, subjective sleepiness, reaction times and fatigue scores all remained elevated above baseline levels in the 27 participants who spent 10 hours in bed on the recovery night.

"The additional hour or two of sleep in the morning after a period of chronic partial sleep loss has genuine benefits for continued recovery of behavioral alertness," said Dinges. "The bottom line is that adequate recovery sleep duration is important for coping with the effects of chronic sleep restriction on the brain."

Extrapolations estimated that at least 10 hours of recovery sleep would be necessary for sleep-restricted participants to match the functional levels of the well-rested control group. However, the authors noted that circadian constraints on sleep duration may prevent individuals from getting enough sleep in one night to achieve recovery. Acute recovery in a single night would be more likely if the sleep restriction is less severe than that which participants experienced in the study.

Dinges also noted that performance and alertness deteriorated profoundly when the five nights of restricted sleep were followed by a night of either no sleep or only two hours of time in bed.

"This highlights the importance of avoiding all-night sleep deprivation following a period of restricted sleep," he said.

Previous research led by Dinges found that even relatively moderate sleep restriction can seriously impair waking neurobehavioral functions in healthy adults. The study published in the journal Sleep in 2003 found that chronic restriction of sleep to six hours or less per night for 14 consecutive days produced cognitive performance deficits equivalent to up to two nights of total sleep deprivation.

In a 2009 study in the journal Sleep, Dinges and Mathias Basner, MD, reported that people who worked eight hours or more woke up earlier in the morning than people who worked less than eight hours, but they did not go to bed earlier at night. The study also found that watching TV was the primary activity people engaged in before going to bed. The authors suggested that giving up some TV viewing in the evening is one strategy to reduce chronic sleep restriction.


Contact: Kathleen McCann
American Academy of Sleep Medicine

Related medicine news :

1. Children have a negative impact on physical activity among individuals with heart disease
2. Executives who take the fewest risks have the most negative emotions
3. Scientists reprogram triple-negative breast cancer cells to respond to tamoxifen
4. Avoid Becoming Social Media Roadkill: Top 5 Ways to Combat Negative Word of Mouth (Free Webinar)
5. Sex lives of patients are negatively affected by RA and SLE
6. Sex lives of patients are negatively affected by rheumatoid arthritis and SLE
7. Smoking cigarettes is a predictor of RA and may negatively impact on efficacy of anti-TNFs
8. False positives in TB diagnosis lead to real negatives for HIV patients
9. Free Yourself from Negative Energetic Influences
10. A new indicator of poor prognosis in node-negative colorectal cancer patients
11. People with anxiety disorder less able to regulate response to negative emotions, study shows
Post Your Comments:
(Date:11/30/2015)... ... November 30, 2015 , ... ... companies, announced today that it has officially launched a sleek, mobile-ready and user-centric ... that his company’s new website clearly outlines the benefits that its SEO services ...
(Date:11/30/2015)... Garden City, NY (PRWEB) , ... December 01, ... ... (NAPW) honors Christina Colon as a 2015-2016 inductee into its ... for leadership in pharmacy. NAPW is the nation’s leading networking organization exclusively for ...
(Date:11/30/2015)... ... December 01, 2015 , ... Live Very Well is ... insurance plans on . The multi-carrier insurance exchange platform offers individual ... allowing consumers to compare, quote and match plans to meet their needs. ...
(Date:11/30/2015)... ... November 30, 2015 , ... Stress, anxiety, illness, infection or even a need ... tumors? , Heather Spader, MD, a new pediatric neurosurgeon at Joe DiMaggio Children’s Hospital ... point to tumors. , “Bad headaches that don’t go away, that don’t ...
(Date:11/30/2015)... ... ... MOSI recently added two state-of-the-art augmented reality (AR) experiences from INDE Broadcast ... collection of interactive exhibits within the Kids In Charge! building. In collaboration with the ... closer than ever to a range of animals as they drink, sleep and play ...
Breaking Medicine News(10 mins):
(Date:11/30/2015)... --  Royal Philips  (NYSE: PHG ; AEX: ... a fully integrated, consultative approach to enhance radiology ... management approaches that combine imaging systems, services, informatics ... delivery and reduce costs. Making its debut at ... Annual Meeting (RSNA) in Chicago ...
(Date:11/30/2015)... CHICAGO , Nov. 30, 2015 Nautilus ... next-generation Radiology Image Management platform ( ). The ... was announced from RSNA 2015 (Radiology Society North America) ... Radiology conference in the U.S. --> ... radiology platform that enables access to radiology studies worldwide ...
(Date:11/30/2015)... (HK$,000)For the Six Months Ended 30 September 2015 2014RestatedChange%Turnover 545,575 , 518,852 ... , 384,242 , 9.8 Hospital ... , (18.3) Medical Insurance Administration Service Income , ... Medical Devices and Accessories Sales , 89,645 , ... , 2,822 , 2,917 , ...
Breaking Medicine Technology: