Navigation Links
Nearly half of US adults will develop painful knee osteoarthritis by age 85: study

Almost half of all U.S. adults and nearly two-thirds of obese adults will develop painful osteoarthritis of the knee by age 85, a study based at the University of North Carolina at Chapel Hill suggests.

The study also found that a person's lifetime risk rose as their body mass index or BMI increased, with the greatest risk found in those whose weight was normal at age 18 but were overweight or obese at 45 or older.

"These results show how important weight management is for people throughout their lives," said Dr. Joanne Jordan, principal investigator of the Johnston County Osteoarthritis Project and senior study author. "Simply put, people who keep their weight within the normal range are much less likely to develop symptomatic knee osteoarthritis as they get older and thus much less likely to face the need for major surgical procedures, such as knee replacement surgery."

The study also sends an important message to physicians, said Jordan, director of the Thurston Arthritis Research Center and professor of medicine and orthopaedics in the School of Medicine at the University. "They need to include the risk of knee osteoarthritis in the discussion when counseling patients about weight management and they need to factor that risk into their treatment plans."

The results were published in the Sept. 15, 2008 issue of Arthritis Care & Research. Lead author of the report is Louise Murphy, Ph.D. of the Centers for Disease Control and Prevention in Atlanta. Murphy led the data analysis and the CDC is the primary funder of the Johnston County Osteoarthritis Project.

In the study, researchers collected and analyzed data over a 13-year period from 3,068 men and women 45 years old and older who live in Johnston County, N.C. At two separate points during the study, each participant was interviewed at home and given a clinical exam that included taking X-ray images of their knees and measuring their BMI. They were interviewed a second time two weeks after the clinical exam. In addition, researchers calculated the subjects' BMI at age 18 based on their self report of height and weight at that age.

After all data were collected, researchers estimated the lifetime risk of symptomatic osteoarthritis in at least one knee using logistic regression models of statistical analysis. They found that the lifetime risk of symptomatic knee osteoarthritis was 44.7 percent.

There were no significant differences in risk related to a participant's sex, race or education level. However, obese participants had a significantly higher lifetime risk, 64.5 percent compared to 34.9 percent for normal weight and 44.1 percent for overweight participants. Those with a history knee injury also had a higher risk than those without, 56.8 percent compared to 42.3 percent.

A separate analysis of BMI across the span of participants' lives found that those who had a normal weight at age 18 and at their baseline and follow up visits had the lowest risk (29.2 percent) while those who reported a normal weight at 18 but were overweight or obese at the two later time points had the highest risk (59.9) percent.

Although the participants in this study all live in the same relatively rural county in the South, the lifetime risk of knee arthritis is likely high in the rest of the U.S. as well, the researchers wrote. They concluded that the study "underscores the need for public health weight loss and management interventions" that would help decrease the risk.


Contact: Stephanie Crayton
University of North Carolina School of Medicine

Related medicine news :

1. New AHRQ Study Finds Surgical Errors Cost Nearly $1.5 Billion Annually
2. Hospital Expenditures for Physician On-Call Pay Rates Nearly Double
3. New Research Shows Cadaver Tissue Fails Nearly a Quarter of the Time in Young, Athletic ACL Reconstruction Patients
4. New Research Shows Cadaver Tissue Fails Nearly a Quarter of the Time in Young, Athletic ACL Reconstruction Patients
5. Cadaver tissue fails nearly 25 percent of the time in young ACL reconstructions
6. St. Louis Park Vapor Systems Installation Nearly Complete; Meeting July 10
7. International Living Ultimate Event Attracts Nearly 300 Attendees Who Explore the Growing Trend of Retiring Overseas
8. 19th Annual Susan G. Komen National Race for the Cure(R) Draws Nearly 50,000 Participants, Celebrities; Brings Record Funds to National Capital Area
9. Nearly 1 in 5 teenagers admit eating problems, but anxiety is a bigger problem than appearance
10. Do It Now College Program Registers Nearly 125,000 New Organ and Tissue Donors
11. Nearly 40 Percent of GERD Patients Taking PPIs Experience Recurring Symptoms
Post Your Comments:
(Date:12/1/2015)... ... 01, 2015 , ... Physicians’ Education Resource®, LLC (PER®) ... announced that the first annual School of Gastrointestinal Oncology™ (SOGO™) will be held ... treatment of gastrointestinal cancers are undergoing transformational change, providing oncologists with powerful new ...
(Date:12/1/2015)... (PRWEB) , ... December 01, 2015 , ... Growth in ... part due to decreases in utilization of hospital and nonhospital care, according to a ... CompScope™ Medical Benchmarks for Louisiana, 16th Edition , found medical payments per claim with ...
(Date:12/1/2015)... Illinois (PRWEB) , ... December 01, 2015 , ... ... and share medical images have been lifted as IMAGE Information Systems launches MED-TAB™ ... Society of North America Annual Meeting from November 29 to December 4, 2015. ...
(Date:12/1/2015)... ... December 01, 2015 , ... Visage accelerates ... a wholly owned subsidiary of Pro Medicus Ltd. (ASX: PME), has announced they ... Society of North America (RSNA) 2015 annual meeting through December 3 in Chicago, ...
(Date:12/1/2015)... CA (PRWEB) , ... December 01, 2015 , ... ... and clinical solutions for the care management and population health arenas, is pleased ... providing clinical and cost containment services, has successfully implemented the ACUITY Complete Care™ ...
Breaking Medicine News(10 mins):
(Date:12/1/2015)... DUBLIN , Dec. 01, 2015 /PRNewswire/ ... announced the addition of the "Medium ... Adhesives, Sealants, Lubricants, and Other Applications - ... and Forecast, 2015 - 2023" report ... ) has announced the addition of the ...
(Date:12/1/2015)... 2015   Nottingham Spirk , a leading ... publication of a free whitepaper , "The ... The whitepaper gives medical product companies, pharmaceutical manufacturers ... lucrative segment. Nottingham Spirk survey ... their own health, save money (i.e., fewer doctors, ...
(Date:12/1/2015)... Dec. 1, 2015 Array BioPharma ... that its Chief Executive Officer, Ron ... Annual Healthcare Conference in New York.  The ... conference through a webcast on the Array ... , --> , ...
Breaking Medicine Technology: