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Nearly 800,000 deaths prevented due to declines in smoking
Date:3/14/2012

and policies.

In 2011, researchers conducting the National Lung Screening Trial (NLST) found that screening heavy smokers with low-dose spiral CT reduced lung cancer mortality by 20 percent, compared to standard chest X-ray (for more information, see the press release on this study). Even with the potential mortality benefits associated with screening, continued implementation of evidence-based tobacco control policies, programs, and services remains a critical approach to reducing the burden of lung cancer, according to the authors.

CISNET is a consortium of NCI-sponsored investigators who use statistical modeling to improve our understanding of cancer control interventions in prevention, screening, and treatment. This modeling approach, which has been validated in several previous studies, can be used to guide public health research and priorities. The network is working on a project to study the efficacy of lung cancer screening for smokers in different age and exposure level groups, based on the results of benefit for spiral CT screening found in the NLST for heavy smokers.

The results discussed in the paper are based on six different models, developed by members of the CISNET network. The centers that created these models include Erasmus Medical Center, The Netherlands; Fred Hutchinson Cancer Research Center, Seattle; Pacific Institute for Research and Evaluation, Calverton, Md.; Rice University-M.D. Anderson Cancer Center, Houston; Massachusetts General Hospital-Harvard Medical School, Boston; and Yale University, New Haven, Conn. More details about the construction of models will be published in a forthcoming special issue of Risk Analysis An International Journal.


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Source:Eurekalert  

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