Navigation Links
Natural products from plants protect skin during cancer radiotherapy
Date:7/24/2014

Radiotherapy for cancer involves exposing the patient or their tumor more directly to ionizing radiation, such as gamma rays or X-rays. The radiation damages the cancer cells irreparably. Unfortunately, such radiation is also harmful to healthy tissue, particularly the skin over the site of the tumor, which is then at risk of hair loss, dermatological problems and even skin cancer. As such finding ways to protect the overlying skin are keenly sought.

Writing in the International Journal of Low Radiation, Faruck Lukmanul Hakkim of the University of Nizwa, Oman and Nagasaki University, Nagasaki, Japan, and colleagues there and at Macquarie University, New South Wales, Australia, Bharathiar University, India and Konkuk University, South Korea, explain how three ubiquitous and well-studied natural products derived from plants can protect the skin against gamma radiation during radiotherapy.

Hakkim and colleagues discuss the benefits of the organic, antioxidant compounds caffeic acid (CA), rosmarinic acid (RA) and trans-cinnamic acid (TCA) used at non-toxic concentrations. They tested the radio protective effect of these compounds against gamma-radiation in terms of reducing levels of reactive oxygen species generated in skin cells by clinical relevance dose of gamma ray in the laboratory and in terms of the damage to the genetic material DNA, specifically double strand breaks in laboratory samples of human skin cells (keratinocytes). They found that treating the human skin cells with CA, RA and TCA can protected the cells by 40, 20 and 15 percent respectively from gamma ray toxicity. They suggest that the protective effect arises because the compounds mop up the reactive oxygen species and chemically deactivate them as well as enhancing the body's natural DNA repair mechanisms.

The team suggests that these compounds might best be used as skin protectants during combination chemo- and radio-therapy. Further work is under way to investigate the clinical potential of mixtures of the three natural products.


'/>"/>

Contact: Albert Ang
press@inderscience.com
Inderscience Publishers
Source:Eurekalert

Related medicine news :

1. EPA to Cut Air Pollution from Natural Gas Fracking
2. Soybeans soaked in warm water naturally release key cancer-fighting substance
3. Science of parenting, the link between sexism and racism, death and the supernatural, and more
4. Novel Natural Sciences Repository Opens Web Portal
5. Study examines use of a natural language processing tool for electronic health records in assessing colonoscopy quality
6. Acne No More Review Explores Product Aimed at Curing Acne Naturally
7. Natural Sciences Repository Publishes Chromatography and Acidic Compounds Resources
8. Under Right Conditions, Fertility Treatment Can Equal Natural Conception Rates: Study
9. Success of fertility treatment may approach natural birth rate
10. GTC Green Cleaning Products Now Available from UNFI - United Natural Foods
11. Stimulant marketed as natural in sports supplement actually of synthetic origin
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/29/2016)... ... April 29, 2016 , ... Conditions were ideal for Global Lyme Alliance’s ... Sunday, with sunny skies, a light breeze and temperatures in the 60s. Over 400 ... 5k Run and Walk and 1-mile walk were held to increase awareness about ...
(Date:4/29/2016)... ... April 29, 2016 , ... The Wharton ... $30,000 Perlman Grand Prize of the 2016 Wharton Business Plan Competition —as ... People’s Choice Award, and the Committee Award for Most ‘Wow Factor,’ making them ...
(Date:4/29/2016)... ... ... type of skin cancer. Although only about 1 percent of skin cancer cases are melanoma, ... are expected to die of melanoma this year. The risk increases with age, and while ... diagnosed cancers in young women. A recent breakthrough in genetic studies may give doctors the ...
(Date:4/29/2016)... Grants Pass, OR (PRWEB) , ... April 29, 2016 , ... ... nutritionists suggest dinner as the meal to miss. That was among the many new ... True Nutrition, on a recent Sharon Kleyne Hour® Power of Water® radio show. Bonny ...
(Date:4/29/2016)... ... April 29, 2016 , ... ... media enterprise focused entirely on patients with cancer, today announced that Lynne Malestic, ... as the 2016 CURE® Extraordinary Healer® for Oncology Nursing , which honors ...
Breaking Medicine News(10 mins):
(Date:4/29/2016)... April 29, 2016 ... Financier Sanofi, leader mondial ... ses résultats pour le premier trimestre ... Jérôme Contamine, commente les résultats du ... perspectives pour le reste de l,année. ...
(Date:4/29/2016)... -- Automation is one of the best ... growing demands for productivity in speed, accuracy, throughput and ... already adept of a wide range of functions that ... Instrumentation continues to evolve, and is poised to tackle ... years ago. Originally used mostly by the big pharmaceutical ...
(Date:4/28/2016)... 2016  While Abbott,s announced purchase of St. ... repair and stent business, healthcare research firm Kalorama ... firmly into patient monitoring.  Kalorama said that patient ... areas, with double-digit growth expected the next 5 ... Remote Patient Monitoring . Abbott Laboratories agreed ...
Breaking Medicine Technology: