Navigation Links
Natural Killer Cells May Help Protect Against New Strains of Influenza Virus

*Swine Flu Outbreak Highlights Influenza Virus Research at Drexel University*

PHILADELPHIA, May 1 /PRNewswire/ -- Research conducted at Drexel University has demonstrated the importance of natural killer, or NK, cells in controlling primary influenza virus infection. These findings may help us understand how the body's immune system may best respond to the newly emergent swine flu.

While no studies have been conducted on the specific H1N1 strain of influenza virus referred to as "swine flu," Drexel researchers have asked the question "How does the immune system respond the first time it encounters a new strain of influenza virus?"

Using a mouse model of primary influenza virus infection, Dr. Barry W. Ritz, Research Assistant Professor in the Department of Biology of Drexel University, and colleagues have demonstrated that NK cells, specialized white blood cells that participate in innate or non-specific immunity, help control influenza virus early during an infection. Specifically, the studies demonstrate that NK cells are essential in controlling lung virus titers early during an influenza virus infection and that NK cell function decreases with old age.

Dr. Ritz: "NK cells are among the earliest responders to influenza virus infection and help control the infection, and because NK cells are non-specific in their response to influenza virus infection, they respond similarly no matter the source of the infection."

Dr. Ritz and colleagues have also studied the importance of nutritional status and specific nutritional interventions to support NK cell activity in response to influenza virus infection.

Dr. Ritz: "Certain nutritional interventions, or nutraceuticals, appear to have a positive effect on the NK cell response to influenza virus infection."

For example, Dr. Ritz has published several papers in the peer-reviewed journals Nutrition Research, Journal of Nutrition and Nutritional Reviews demonstrating that supplementation with a medicinal mushroom based compound called Active Hexose Correlated Compound (AHCC) increases the non-specific NK cell response to primary influenza virus infection, increases survival, and results in a less severe infection. This work was sponsored by Amino Up Chemical Company, Sapporo, Japan. Similarly, Dr. Ritz is currently studying the potential NK cell supportive properties of a bovine colostrum preparation, supported by La Belle, Inc., Bellingham, WA.

Dr Ritz cautions: "It remains unknown what, if any, effects these nutritional interventions would have on the immune response to swine flu."

About the Department of Biology, College of Arts & Sciences, Drexel University: The Department of Biology at Drexel University offers studies in wide-ranging aspects of the life sciences leading to Baccalaureate, Master's, and Doctoral degrees. Our 31 faculty members and scientists are passionately involved in teaching and conducting research in Cellular and Molecular Biology, Ecology and Environmental Science, Organism Physiology and Development, Microbial Pathogenesis and Immunology, and Nutrition and Food.

About Active Hexose Correlated Compound (AHCC): AHCC is a unique natural compound derived from the hybridization of several subspecies of medicinal mushrooms. AHCC is utilized by several hundred hospitals and healthcare facilities throughout Asia as a complimentary dietary supplement for incoming patients to help reduce the risk of hospital viruses and infections and it is used by tens of thousands of individuals around the world for daily immune support. More than 20 research papers on AHCC have been published in peer-reviewed medical journals.

About Bovine Colostrum: Colostrum is the first lacteal secretions produced by a mammal prior to and just after giving birth. Colostrum is full of rich nutrients and immune factors that set babies on the path to health. Bovine colostrum is extremely similar to human colostrum in terms of digestibility and nutrients. At the same time, scientific studies have shown that colostrum's highly prized immune and growth factors are found in greater quantities in bovine colostrum than in human.

    Nogusa S, Gerbino J, Ritz BW.  Low-dose supplementation with active hexose
       correlated compound improves the immune response to acute influenza
       infection in C57BL/6 mice. Nutr Res. 2009;29(3):139-43.
    Ritz BW. Supplementation with active hexose correlated compound increases
       survival following infectious challenge in mice. Nutr Rev.
    Ritz BW, Aktan I, Nogusa S, Gardner EM. Energy restriction impairs natural
       killer cell function and increases the severity of influenza infection
       in young adult C57BL/6 male mice. J Nutr. 2008;138:2269-2275.
    Nogusa S, Ritz BW, Kassim SH, Jennings SR, Gardner EM. Characterization of
       age-related changes in natural killer cells during primary influenza
       infection in mice. Mech Age Devel. 2008;129:223-30.
    Ritz BW, Nogusa S, Ackerman EA, Gardner EM. Supplementation with Active
       Hexose Correlated Compound increases the innate immune response of
       young mice to primary Influenza Infection. J Nutr. 2006;136:2868-73.

SOURCE AHCC Research Association
Copyright©2009 PR Newswire.
All rights reserved

Related medicine news :

1. Zatik Organic Beauty Care Lunch Seaweed-Herbal Wrinkle Reduction and Natural Skin Whitening Products
2. All Natural System Sweeps Swine Flu Out with the Trash
3. Scent To Sleep All Natural Non-Drowsy Sleep Mist Acquired by Innovative Custom Products, Inc. (ICP)
4. BODY WORLDS Exhibition Uses Lung Specimens to Launch Anti-Smoking Campaign at the San Diego Natural History Museum
5. Natural Products Association Announces Chondroitin Testing Results For Greentech
6. PlumSmart Plum Juice Clinically Proven to Help Regulate Digestion, Naturally
7. Introducing solixir(TM)... The First All-Natural Sparkling Botanical Beverage to Hydrate Body and Soul
8. Naturally fluorescent molecules may serve as cancer biomarker
9. Ear Health News: Natural Treatments to Ease Tinnitus Intensity
10. Natural & Organic Coupon Site Offers Consumers Real-Time Savings Alerts
11. Free iPhone Natural Cures App Launched by Jacob Teitelbaum, MD
Post Your Comments:
(Date:11/29/2015)... (PRWEB) , ... November 30, 2015 , ... The Cyber Monday deal is a deep ... is the right time to get gifts for the skin care lover in your circle. ... filled with serums . This year, the 3 serums are staples: Collagen, Retinol and Hyaluronic ...
(Date:11/29/2015)... ... 29, 2015 , ... ProStatic Analog Distortion from Pixel Film ... for Final Cut Pro X. FCPX users can now apply distortion ... Destoying and creating chaotic distortion is now quick and simple, putting film makers ...
(Date:11/28/2015)... ... 2015 , ... Trying to relax on a couch can actually be uncomfortable, ... this design due to personal experience with a bad back," he said. , This ... as well as increases support. It also makes it easier to eat, do other ...
(Date:11/27/2015)... ... November 27, 2015 , ... According to an article published November ... and the University of British Columbia suggested that laws requiring bicyclists to wear helmets ... that part of the reason for the controversial conclusion is that, while helmets have ...
(Date:11/27/2015)... PITTSBURGH, PA (PRWEB) , ... November 27, 2015 ... ... of how filthy the toilets were," said an inventor from Hillside, N.J. "Many ... this improved seat cover so that individuals will always be protected from germs." ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... 2015 ) has ... of High Viscosity Drugs" report to their ... the addition of the "Self Administration of ... --> Research and Markets ( ... "Self Administration of High Viscosity Drugs" report ...
(Date:11/26/2015)... , November 26, 2015 /PRNewswire/ ... announced the addition of the  "2016 ... the European Cell Surface Marker Testing ... Opportunities"  report to their offering.  ... the addition of the  "2016 Future ...
(Date:11/25/2015)... Calif. , Nov. 25, 2015  Amgen (NASDAQ: ... Biologics License Application (BLA) with the United ... for ABP 501, a biosimilar candidate to Humira ® ... adalimumab biosimilar application submitted to the FDA and represents ... Sean E. Harper , M.D., executive vice ...
Breaking Medicine Technology: