Natura Therapeutics and USF receive NIH grant to study green tea compound for A...(ect to clearly define this non-amyloidog...),Health

Date:6/3/2009

ect to clearly define this non-amyloidogenic mechanism and identify the potential molecular drug targets essential for formulating novel, effective treatments against AD," explained Cyndy D. Sanberg, Ph.D., senior vice president of Natura Therapeutics, Inc. and the other PI on the grant.

Tests, including cognitive tests, will use mouse models for oral administration of TeaMem to a prophylactic treatment group that will be compared to a second group with AD-like pathology. Groups will be compared for the effect of reducing AD-like pathology and behavioral impairment. The studies, said Tan, could lay the groundwork for AD clinical trials in humans in the near future.

In their 2008 report, the Alzheimer's Association (www.alz.org) noted that AD was the nation's sixth leading cause of death and predicts 10 million baby boomers will develop AD. The direct and indirect costs of AD exceed $148 billion annually, said the Association.

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Contact: Dr. Jun Tan jtan@health.usf.edu 813-974-9326 University of South Florida Health Source:Eurekalert

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