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Natreon is Granted a U.S. Patent on its CROMINEX® Product

Natreon has been granted a U.S. Patent (10,183,047, January 22, 2019) on its Crominex®3+, a composition of trivalent chromium chloride combined with extracts of amla and shilajit, that has a synergistic effect on improving lipid profile and endothelial function. This newly granted patent, along with 7 clinical studies on Crominex®3+, establish this ingredient as the ideal product for supporting heart health. This expands Natreon’s strong patent portfolio to 28 domestic and international active patents.

“We are glad that USPTO has granted a well-deserved patent for cardiovascular health benefits of Crominex®3+, the most efficacious of several chromium supplements from the market. Crominex®3+ has amazing synergistic activity that showed significant improvement in endothelial function, lipid profile, hsCRP, as well as HbA1c, which are all important factors for cardiovascular health. Synergistic activity of Crominex®3+ is achieved by using totally natural materials,” said Dr. Sanni Raju, CEO of Natreon.

Two additional clinical studies (to be published soon), show combining only 10-20 mg of Crominex®3+ (200 mcg to 400 mcg of trivalent chromium) with 2 g of fish oil (600 mg of EPA + 400 mg of DHA) enhances the health benefits of fish oil significantly.

“It is interesting to note that 10-20 mg of Crominex®3+ neither increases the size of the fish oil dosage form nor impacts the cost significantly, while enhancing fish oil’s numerous cardiovascular health benefits,” says Dr. Sanni Raju, CEO of Natreon.

About Crominex®:
Crominex®3+ is a complex of trivalent chromium (Cr3+) chloride with standardized extracts of the edible fruits of Phyllanthus emblica (amla), an Ayurvedic superfruit, and shilajit, an herbo-mineral compound from the Himalayan mountains. The polyphenolic compounds in the P. emblica extract not only contribute to a host of heart health benefits, but also help keep the Cr3+ from converting to chromium Cr6+. Furthermore, the liposomal fulvic acid in the Shilajit extract improves absorption of the complex, as it is known to enhance bioavailability of trace minerals.
With its synergistic beneficial properties, Crominex®3+ is a unique and dynamic solution for heart health and healthy aging with minimal cost. As with all Natreon ingredients, Crominex®3+ is GRAS-affirmed and non-GMO Project Verified. Visit:

About Natreon:
Natreon is at the forefront of nutritional ingredient innovation, quality and research. For over 20 years, Natreon has been offering scientifically validated Ayurvedic ingredients to the industry. Natreon’s extracts are purified and standardized using proprietary process technology and controls that result in optimal levels of bioactive constituents. Natreon uses sustainable sources for the raw herbs through an integrated supply chain to ensure quality and potency. Natreon has its global headquarters in New Jersey and a state-of-the-art R&D facility in Kolkata, India. For more information, visit:

Dr. Sanni Raju, CEO/Chairman or Bruce Brown, President
2-D Janine Place
New Brunswick, NJ 08901

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