Professor Alan Silman, Medical Director of the Arthritis Research Campaign, said: "Pain is the number one concern for all patients with arthritis, and there have been too few recent advances in how to manage it. Several million people suffer both day and night, with only conventional painkillers helping to keep the pain at bay.
"Our new centre is charged with a truly innovative approach; covering the basic pathways of pain perception and the changes in the tissues caused by arthritis to identify completely new targets for developing effective, safe and acceptable treatments."
Professor David Greenaway, Vice-Chancellor of The University of Nottingham, said: "This significant research award will harness the considerable expertise of researchers in The University of Nottingham's Department of Academic Rheumatology within our School of Clinical Sciences.
"Working across the University and with our partner NHS Trusts as an Arthritis Research Campaign centre of excellence, this innovative research team has the prospect of finding vital solutions to the terrible pain caused by osteoarthritis for many millions of people in the UK and worldwide," said Professor Greenaway. "The University has committed additional funding to supporting this research centre's success."
Osteoarthritis is the most common type of arthritis. It affects several million older people in the UK. There is currently no cure for it, so the emphasis is on effective treatment. A major cause of disability, it occurs when cartilage the lubricating substance between joints is diseased, leading to stiffness and pain.
Current drug treatments to relieve the pain of osteoarthritis are unsatisfactory, and although exercise, weight loss and self-management help some sufferers, many more people struggle to find adequate, side-effect-free pain relief. Joint replacement surgery is available for people with severe, un
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University of Nottingham