Navigation Links
National Jewish Health researchers awarded $13 million to evaluate treatments for toxic gases
Date:10/13/2011

National Jewish Health researchers have received nearly $13 million from the National Institutes of Health to evaluate potential rescue medications for victims of terrorist attacks, wartime use of toxic gases, and/or inhalation disasters. The gases of greatest interest in these studies will be 'mustard gas' (sulfur mustard) and chlorine gas.

"The excitement about these studies is that they are designed to provide rescue treatments," said Carl White, MD, principal investigator of the grant.

The grant, part of the NIH's Countermeasures Against Chemical Threats Research Network (CounterACT), is for 5 years. The rescue agents to be given greatest study in these trials will include fibrinolytics ('clot busters'), anticoagulants, catalytic antioxidants, and flavonoids (specific herbal remedies). Researchers will evaluate models of damage to the lungs and airways and to skin.

"We have already found very encouraging preliminary data in which some of our agents can be effective even when given several hours after the toxic inhalation," said Dr. White. "This is important because real world conditions can cause minutes to hours of delay in getting to victims of such tragedies."

The work involves collaborations between two teams of investigators at National Jewish Health and one from the University of Colorado School of Pharmacy, as well as a collaborating center at the U.S. Army Medical Research Institute of Chemical Defense (USAMRICD).

"The drugs we are testing work through several different mechanisms so that they may prevent or limit progressive damage to airways or skin, as well as prevent or clear blockage of airways," said Dr. White. "It is also exciting that some of the treatments we develop may also carry over to other difficult lung diseases of childhood and adults."

The initial focus of the research is on the acute injury to lungs and skin occurring in the first 24-48 hours of exposure. As the studies progress over the next several years, researchers hope to evaluate the ability of our relatively early interventions to prevent lung fibrosis and bronchiolitis obliterans that can result from such exposures.


'/>"/>
Contact: William Allstetter
allstetterw@njhealth.org
303-398-1002
National Jewish Health
Source:Eurekalert

Related medicine news :

1. NationalCreditReport.com Reminds Consumers of Ways to Improve Credit Report and Score in 2010
2. The National Coalition for Cancer Survivorship Joins the Commission on Cancer
3. National Wildlife Federation Says Outdoor Time for Kids Can Help First Lady Achieve Her “Let's Move” Goal
4. Howard Dean to Speak at the 2010 DTC National Conference
5. International Diabetes Federation awards $2 million to 9 global diabetes research projects
6. Jion Beijing Great Wall International Travel Agency Immediate Exposure to China Expo 2010
7. U.S. National Guard Connects Nationwide with Desktop Alert's Command and Control Mass Notification Systems and Common Alerting Protocol (CAP)
8. H1N1 international symposium to be hosted by Emory-UGA Influenza Center
9. The Alliance for a Healthier Generation Names Celtics Captain Paul Pierce National Athlete Spokesperson in the Fight Against Childhood Obesity
10. Researchers Who Discovered First Genes for Stuttering will Present Findings to the National Stuttering Association
11. Protecting patients: Study shows that Johns Hopkins flu vaccination rates twice national average
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... Apple ... care services, staged a mock evacuation of the facility as part of a disaster ... Fire Department, Echo Hose EMS and Shelton City Emergency Manager, as well as the ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Global Healthcare Management’s ... Alexandria Park in Milford, NJ. This free event, sponsored by Global Healthcare Management’s ... The fun run is geared towards children of all ages; it is a ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the ... danger possible to save lost souls in the Philippines. “The Journey: From the Mountains ... a dedicated teacher of the Bible. She has taught all ages and currently teaches ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the largest and ... plans to open a flagship location in Covington, LA at 401 N. U.S. Highway ... store next to Office Depot in the Holiday Square shopping center. Its location allows ...
(Date:10/12/2017)... ... 2017 , ... Asante, a nationally recognized health system in ... existing home health joint venture through an agreement, effective October 1, 2017, to ... home health company with Asante, delivering clinically integrated care, for the past eight ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... -- NDS received FDA 510(k) clearance in May 2017 for its highly ... designed for endoscopy environments. An innovative secondary monitor solution, ZeroWire ... support the improvement of patient outcomes, procedural efficiency, and the lowering ... ... ...
(Date:10/4/2017)... 4, 2017  South Korean-based healthcare product Development Company ... "cprCUBE" on Kickstarter. The device will educate the user ... with better efficiency compared to the dated and pricey ... on efficacy of the compression for a more informed ... goal to raise $5,000. ...
(Date:10/2/2017)... 2017  Eli Lilly and Company (NYSE: ... third quarter of 2017 on Tuesday, October 24, 2017. ... day with the investment community and media to further ... call will begin at 9 a.m. Eastern time. Investors, ... webcast of the conference call through a link that ...
Breaking Medicine Technology: