Brinker, who is co-principal investigator on the grant with Willman and a distinguished professor of chemical and nuclear engineering at UNM, used a Sandia-funded Laboratory Directed Research and Development (LDRD) grant to conduct preliminary research in nanofabrication. The nanostructures he developed form the basis for delivering drugs directly to a wide variety of cancer targets, a method that increases the drug's effectiveness and reduces side effects. "The technology I developed with now-Truman Fellow Carlee Ashley and UNM colleagues is really a generic platform to target any arbitrary cancer, so we've already written other proposals and are interacting with other cancer research centers throughout the U.S. and Canada, to go after low-outcome cancers like breast, lung, pancreatic, and liver," Brinker said.
Brinker is also a team leader in the Cancer Nanotechnology Training Center, which is focused on training multidisciplinary scientists at both Sandia and UNM. One such student, Ashley, started working as an undergraduate student in Brinker's lab in Sandia's Advanced Materials Laboratory. Brinker then served as her graduate co-advisor with David Peabody of UNM, and Ashley recently earned one of Sandia's prestigious Truman Fellowships. "Carlee's experience was the model for the training grant. Her work was used as the basis for what we'd like to do in the future," Brinker said. "She went from biochemistry to training in my lab and then chemical engineering. That kind of interdisciplinary training is something that Sandia and UNM are actively encouraging."
The next five years of the NCI's Alliance program focus on rapidly advancing new nanotechnology discoveries and sp
|Contact: Stephanie Hobby|
DOE/Sandia National Laboratories